- Home
- Publications
- Publication Search
- Publication Details
Title
CAR-NK Cells: From Natural Basis to Design for Kill
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-12-14
DOI
10.3389/fimmu.2021.707542
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Non‐clinical efficacy, safety, and stable clinical cell processing of iPSC‐derived anti‐GPC3 CAR‐expressing NK/ILC cells
- (2020) Tatsuki Ueda et al. CANCER SCIENCE
- The therapeutic landscape for cells engineered with chimeric antigen receptors
- (2020) Matthew MacKay et al. NATURE BIOTECHNOLOGY
- Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
- (2020) Enli Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia
- (2020) Stephan Müller et al. Frontiers in Immunology
- NK Cell-Based Immune Checkpoint Inhibition
- (2020) Muhammad Khan et al. Frontiers in Immunology
- Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)
- (2020) Julia Hambach et al. Cells
- Editorial: Emerging Concepts on the NKG2D Receptor-Ligand Axis in Health and Diseases
- (2020) Nadia Guerra et al. Frontiers in Immunology
- DNAM1 and 2B4 Costimulatory Domains Enhance the Cytotoxicity of Anti-GPC3 Chimeric Antigen Receptor-Modified Natural Killer Cells Against Hepatocellular Cancer Cells in vitro
- (2020) Yao Huang et al. Cancer Management and Research
- PD-L1 targeting high-affinity NK (t-haNK) cells induce direct antitumor effects and target suppressive MDSC populations
- (2020) Kellsye P Fabian et al. Journal for ImmunoTherapy of Cancer
- CAR-modified memory-like NK cells exhibit potent responses to NK-resistant lymphomas
- (2020) Margery Gang et al. BLOOD
- A novel chimeric PD1-NKG2D-41BB receptor enhances antitumor activity of NK92 cells against human lung cancer H1299 cells by triggering pyroptosis
- (2020) Chengui Lu et al. MOLECULAR IMMUNOLOGY
- Targeting NK Cell Checkpoint Receptors or Molecules for Cancer Immunotherapy
- (2020) Cai Zhang et al. Frontiers in Immunology
- Use of Cell and Genome Modification Technologies to Generate Improved “Off-the-Shelf” CAR T and CAR NK Cells
- (2020) Michael A. Morgan et al. Frontiers in Immunology
- Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor
- (2020) Ying Gong et al. Molecular Therapy-Methods & Clinical Development
- Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells
- (2020) May Daher et al. BLOOD
- CAR-NK cells: A promising cellular immunotherapy for cancer
- (2020) Guozhu Xie et al. EBioMedicine
- Tumor-Infiltrating Natural Killer Cells
- (2020) Beatriz Cózar et al. Cancer Discovery
- Natural Killer Cells and Current Applications of Chimeric Antigen Receptor-Modified NK-92 Cells in Tumor Immunotherapy
- (2019) Jianguang Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Overcoming Resistance to Natural Killer Cell Based Immunotherapies for Solid Tumors
- (2019) Gaurav Nayyar et al. Frontiers in Oncology
- Chimeric Antigen Receptor T Cell Therapy for Solid Tumors: Current Status, Obstacles and Future Strategies
- (2019) Benjamin Heyman et al. Cancers
- Human NK cells: surface receptors, inhibitory checkpoints, and translational applications
- (2019) Simona Sivori et al. Cellular & Molecular Immunology
- Induction of human pluripotent stem cell-derived natural killer cells for immunotherapy under chemically defined conditions
- (2019) Hiroyuki Matsubara et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- 3D model for CAR‐mediated cytotoxicity using patient‐derived colorectal cancer organoids
- (2019) Theresa E Schnalzger et al. EMBO JOURNAL
- Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells
- (2019) Takahiro Kamiya et al. JOURNAL OF CLINICAL INVESTIGATION
- 2B4 costimulatory domain enhancing cytotoxic ability of anti-CD5 chimeric antigen receptor engineered natural killer cells against T cell malignancies
- (2019) Yingxi Xu et al. Journal of Hematology & Oncology
- Mechanisms of natural killer cell‐mediated cellular cytotoxicity
- (2019) Isabel Prager et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation
- (2019) Adam C. Wilkinson et al. NATURE
- Imbalance of Genes Encoding Natural Killer Immunoglobulin-like Receptors and Human Leukocyte Antigen in Patients With Biliary Cancer
- (2019) Martin Cornillet et al. GASTROENTEROLOGY
- Cellular therapy: Adoptive immunotherapy with expanded natural killer cells
- (2019) Dean A. Lee IMMUNOLOGICAL REVIEWS
- Target selection for CAR-T therapy
- (2019) Jianshu Wei et al. Journal of Hematology & Oncology
- Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
- (2019) Anna M. Paczulla et al. NATURE
- Gene editing for immune cell therapies
- (2019) Stefanie R. Bailey et al. NATURE BIOTECHNOLOGY
- The mechanism of anti-PD-L1 antibody efficacy against PD-L1 negative tumors identifies NK cells expressing PD-L1 as a cytolytic effector
- (2019) Wenjuan Dong et al. Cancer Discovery
- Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation
- (2019) Daniela Pende et al. Frontiers in Immunology
- Cancer Immunotherapy Based on Natural Killer Cells: Current Progress and New Opportunities
- (2019) Weilei Hu et al. Frontiers in Immunology
- PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells
- (2019) Silvia Pesce et al. Frontiers in Immunology
- Does Natural Killer Cell Deficiency (NKD) Increase the Risk of Cancer? NKD May Increase the Risk of Some Virus Induced Cancer
- (2019) Won Young Moon et al. Frontiers in Immunology
- An Historical Overview: The Discovery of How NK Cells Can Kill Enemies, Recruit Defense Troops, and More
- (2019) Massimo Vitale et al. Frontiers in Immunology
- Effect of Pembrolizumab After Stereotactic Body Radiotherapy vs Pembrolizumab Alone on Tumor Response in Patients With Advanced Non–Small Cell Lung Cancer
- (2019) Willemijn S. M. E. Theelen et al. JAMA Oncology
- Combination Immunotherapy with CAR T Cells and Checkpoint Blockade for the Treatment of Solid Tumors
- (2019) Rachel Grosser et al. CANCER CELL
- Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System Manufacturing
- (2019) Constanze Radek et al. HUMAN GENE THERAPY
- Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells
- (2019) Evelyn O. Ojo et al. Scientific Reports
- The Rise of NK Cell Checkpoints as Promising Therapeutic Targets in Cancer Immunotherapy
- (2019) Haoyu Sun et al. Frontiers in Immunology
- Corrigendum: A Distinct Subset of Highly Proliferative and Lentiviral Vector (LV)-Transducible NK Cells Define a Readily Engineered Subset for Adoptive Cellular Therapy
- (2019) Rafijul Bari et al. Frontiers in Immunology
- Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector
- (2019) Aurelien B. L. Colamartino et al. Frontiers in Immunology
- CXCR1 Expression to Improve Anti-Cancer Efficacy of Intravenously Injected CAR-NK Cells in Mice with Peritoneal Xenografts
- (2019) Yu Yang Ng et al. Molecular Therapy-Oncolytics
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
- (2018) Jang Hwan Cho et al. CELL
- Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
- (2018) Ye Li et al. Cell Stem Cell
- IPH4102, a monoclonal antibody directed against the immune receptor molecule KIR3DL2, for the treatment of cutaneous T-cell lymphoma
- (2018) Carrie Van Der Weyden et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Chimeric Antigen Receptors in Different Cell Types: New Vehicles Join the Race
- (2018) Dennis C. Harrer et al. HUMAN GENE THERAPY
- Natural killer cell cytotoxicity and its regulation by inhibitory receptors
- (2018) Santosh Kumar IMMUNOLOGY
- CAR T-cell therapy in refractory large B-cell lymphoma
- (2018) Robert Stirrups LANCET ONCOLOGY
- Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity
- (2018) Qing Zhang et al. NATURE IMMUNOLOGY
- Natural killer cell specificity for viral infections
- (2018) Quirin Hammer et al. NATURE IMMUNOLOGY
- Inhibiting TGF-beta signaling preserves the function of highly activated, in vitro expanded natural killer cells in AML and colon cancer models
- (2018) Folashade Otegbeye et al. PLoS One
- Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors
- (2018) Vincent Yi Sheng Oei et al. Cancer Immunology Research
- Enhanced cancer immunotherapy with Smad3-slilencing NK-92 cells
- (2018) Qing Ming Wang et al. Cancer Immunology Research
- The hypoxic tumour microenvironment
- (2018) Varvara Petrova et al. Oncogenesis
- Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer
- (2018) Rohtesh S. Mehta et al. Frontiers in Immunology
- Pharmacologically upregulated carcinoembryonic antigen-expression enhances the cytolytic activity of genetically-modified chimeric antigen receptor NK-92MI against colorectal cancer cells
- (2018) Masayuki Shiozawa et al. BMC IMMUNOLOGY
- Off-the-Shelf CAR-NK Cells for Cancer Immunotherapy
- (2018) Elizabeth L. Siegler et al. Cell Stem Cell
- Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade
- (2018) Joy Hsu et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor Antigen Escape from CAR T-cell Therapy
- (2018) Robbie G. Majzner et al. Cancer Discovery
- Viral and Nonviral Engineering of Natural Killer Cells as Emerging Adoptive Cancer Immunotherapies
- (2018) Sandro Matosevic Journal of Immunology Research
- Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells
- (2018) Nayoung Kim et al. Frontiers in Immunology
- Challenges of NK cell-based immunotherapy in the new era
- (2018) Fang Fang et al. Frontiers of Medicine
- Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
- (2018) Pascale André et al. CELL
- An antibody designed to improve adoptive NK-cell therapy inhibits pancreatic cancer progression in a murine model
- (2018) Jaemin Lee et al. Cancer Immunology Research
- Molecular Mechanisms Directing Migration and Retention of Natural Killer Cells in Human Tissues
- (2018) Roberta Castriconi et al. Frontiers in Immunology
- Purinergic targeting enhances immunotherapy of CD73+ solid tumors with piggyBac-engineered chimeric antigen receptor natural killer cells
- (2018) Jiao Wang et al. Journal for ImmunoTherapy of Cancer
- Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor–Based Immunotherapy and Chemotherapy
- (2017) Rüdiger Klapdor et al. HUMAN GENE THERAPY
- Natural Killer Cells: Angels and Devils for Immunotherapy
- (2017) Beatriz Martín-Antonio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Chimeric antigen receptors for adoptive T cell therapy in acute myeloid leukemia
- (2017) Mingxue Fan et al. Journal of Hematology & Oncology
- Preclinical targeting of aggressive T-cell malignancies using anti-CD5 chimeric antigen receptor
- (2017) K H Chen et al. LEUKEMIA
- Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity
- (2017) E Liu et al. LEUKEMIA
- Engineering Natural Killer Cells for Cancer Immunotherapy
- (2017) Katayoun Rezvani et al. MOLECULAR THERAPY
- Immunotherapy: Tisagenlecleucel — the first approved CAR-T-cell therapy: implications for payers and policy makers
- (2017) Vinay Prasad Nature Reviews Clinical Oncology
- Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma
- (2017) Kevin Bielamowicz et al. NEURO-ONCOLOGY
- NK cell-based immunotherapy for cancer
- (2017) Fang Fang et al. SEMINARS IN IMMUNOLOGY
- First-Ever CAR T-cell Therapy Approved in U.S.
- (2017) Cancer Discovery
- Targeting T-cell malignancies using anti-CD4 CAR NK-92 cells
- (2017) Kevin G. Pinz et al. Oncotarget
- Natural Killer Cells from the Subcutaneous Adipose Tissue Underexpress the NKp30 and NKp44 in Obese Persons and Are Less Active against Major Histocompatibility Complex Class I Non-Expressing Neoplastic Cells
- (2017) Alireza Shoae-Hassani et al. Frontiers in Immunology
- Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an “Off-the-Shelf Immunotherapy” for Improvement in Cancer Treatment
- (2017) Olaf Oberschmidt et al. Frontiers in Immunology
- Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation
- (2017) Federico Simonetta et al. Frontiers in Immunology
- Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity
- (2017) Congcong Zhang et al. Frontiers in Immunology
- Steering CAR T cells to distinguish friend from foe
- (2017) Hillary Caruso et al. OncoImmunology
- Romidepsin alone or in combination with anti-CD20 chimeric antigen receptor expanded natural killer cells targeting Burkitt lymphoma in vitro and in immunodeficient mice
- (2017) Yaya Chu et al. OncoImmunology
- Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes
- (2017) Claudia Piovan et al. Molecular Therapy-Methods & Clinical Development
- Genetic engineering of human NK cells to express CXCR2 improves migration to renal cell carcinoma
- (2017) Veronika Kremer et al. Journal for ImmunoTherapy of Cancer
- Phase II Study of Haploidentical Natural Killer Cell Infusion for Treatment of Relapsed or Persistent Myeloid Malignancies Following Allogeneic Hematopoietic Cell Transplantation
- (2016) Brian C. Shaffer et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Exploitation of natural killer cells for the treatment of acute leukemia
- (2016) Rupert Handgretinger et al. BLOOD
- Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits
- (2016) Kole T. Roybal et al. CELL
- Chimeric antigen receptor-engineered cytokine-induced killer cells overcome treatment resistance of pre-B-cell acute lymphoblastic leukemia and enhance survival
- (2016) Sarah Oelsner et al. INTERNATIONAL JOURNAL OF CANCER
- CD19-CAR engineered NK-92 cells are sufficient to overcome NK cell resistance in B-cell malignancies
- (2016) Annette Romanski et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
- (2016) Meenakshi Hegde et al. JOURNAL OF CLINICAL INVESTIGATION
- CIS is a potent checkpoint in NK cell–mediated tumor immunity
- (2016) Rebecca B Delconte et al. NATURE IMMUNOLOGY
- Targeting natural killer cells in cancer immunotherapy
- (2016) Camille Guillerey et al. NATURE IMMUNOLOGY
- Early treatment of HER2-amplified brain tumors with targeted NK-92 cells and focused ultrasound improves survival
- (2016) Ryan Alkins et al. NEURO-ONCOLOGY
- Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
- (2016) Rizwan Romee et al. Science Translational Medicine
- A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases
- (2016) Xilin Chen et al. Oncotarget
- Chimeric Antigen Receptor-Modified T Cells for Solid Tumors: Challenges and Prospects
- (2016) Yelei Guo et al. Journal of Immunology Research
- Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward the Lymph Node-Associated Chemokine CCL19
- (2016) Mattias Carlsten et al. Frontiers in Immunology
- Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G
- (2016) Sareetha Kailayangiri et al. OncoImmunology
- CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes
- (2016) Wei Hseun Yeap et al. Scientific Reports
- CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
- (2015) S. L. Maude et al. BLOOD
- A Phase I Trial of the Anti-KIR Antibody IPH2101 and Lenalidomide in Patients with Relapsed/Refractory Multiple Myeloma
- (2015) D. M. Benson et al. CLINICAL CANCER RESEARCH
- A phase I/II trial of interleukin-15–stimulated natural killer cell infusion after haplo-identical stem cell transplantation for pediatric refractory solid tumors
- (2015) Antonio Pérez-Martínez et al. CYTOTHERAPY
- TRUCKs: the fourth generation of CARs
- (2015) Markus Chmielewski et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- DAP12-Based Activating Chimeric Antigen Receptor for NK Cell Tumor Immunotherapy
- (2015) Katrin Töpfer et al. JOURNAL OF IMMUNOLOGY
- Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma
- (2015) Nadja Müller et al. JOURNAL OF IMMUNOTHERAPY
- Efficient generation of gene-modified human natural killer cells via alpharetroviral vectors
- (2015) Julia D. Suerth et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor
- (2015) Kurt Schönfeld et al. MOLECULAR THERAPY
- Cyclosporin A and Rapamycin Relieve Distinct Lentiviral Restriction Blocks in Hematopoietic Stem and Progenitor Cells
- (2015) Carolina Petrillo et al. MOLECULAR THERAPY
- Remote control of therapeutic T cells through a small molecule-gated chimeric receptor
- (2015) C.-Y. Wu et al. SCIENCE
- Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma
- (2015) Laura A. Johnson et al. Science Translational Medicine
- Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer
- (2015) David L. Hermanson et al. STEM CELLS
- Targeting the tumor microenvironment to improve natural killer cell-based immunotherapies: On being in the right place at the right time, with resilience
- (2015) Shannon Murray et al. Human Vaccines & Immunotherapeutics
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy
- (2015) Wei Wang Frontiers in Immunology
- Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival
- (2015) Sabrina Genßler et al. OncoImmunology
- CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
- (2015) Jianfeng Han et al. Scientific Reports
- Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein
- (2014) V. Bachanova et al. BLOOD
- Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells
- (2014) C. X. Wang et al. BLOOD
- CXCL10-induced migration of adoptively transferred human natural killer cells toward solid tumors causes regression of tumor growth in vivo
- (2014) Erik Wennerberg et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A Receptor
- (2014) D. Mittal et al. CANCER RESEARCH
- Metastatic Consequences of Immune Escape from NK Cell Cytotoxicity by Human Breast Cancer Stem Cells
- (2014) B. Wang et al. CANCER RESEARCH
- The S1P1 receptor-selective agonist CYM-5442 reduces the severity of acute GVHD by inhibiting macrophage recruitment
- (2014) Qiao Cheng et al. Cellular & Molecular Immunology
- Effect of exposure to interleukin-21 at various time points on human natural killer cell culture
- (2014) Dong-Pyo Lim et al. CYTOTHERAPY
- Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)
- (2014) David Hoskin et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- CTLA-4 Is Expressed by Activated Mouse NK Cells and Inhibits NK Cell IFN- Production in Response to Mature Dendritic Cells
- (2014) A. Stojanovic et al. JOURNAL OF IMMUNOLOGY
- The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions
- (2014) Christopher J Chan et al. NATURE IMMUNOLOGY
- Specific growth inhibition of ErbB2‑expressing human breast cancer cells by genetically modified NK‑92 cells
- (2014) Hui Liu et al. ONCOLOGY REPORTS
- Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity
- (2014) P. S. Adusumilli et al. Science Translational Medicine
- Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment
- (2014) Sergey Rodin et al. Nature Communications
- Targeting CD20+ Aggressive B-cell Non-Hodgkin Lymphoma by Anti-CD20 CAR mRNA-Modified Expanded Natural Killer Cells In Vitro and in NSG Mice
- (2014) Y. Chu et al. Cancer Immunology Research
- Improving the safety of cell therapy products by suicide gene transfer
- (2014) Benjamin S. Jones et al. Frontiers in Pharmacology
- Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition
- (2013) Eric O. Long et al. Annual Review of Immunology
- NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
- (2013) V. Beziat et al. BLOOD
- A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
- (2013) Y.-H. Chang et al. CANCER RESEARCH
- Interaction between natural killer cells and regulatory T cells: perspectives for immunotherapy
- (2013) Isabela Pedroza-Pacheco et al. Cellular & Molecular Immunology
- Treatment of patients with advanced cancer with the natural killer cell line NK-92
- (2013) Torsten Tonn et al. CYTOTHERAPY
- Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC
- (2013) Mirna Balsamo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells
- (2013) Michael C. Jensen et al. IMMUNOLOGICAL REVIEWS
- Retargeting NK-92 for anti-melanoma activity by a TCR-like single-domain antibody
- (2013) Ge Zhang et al. IMMUNOLOGY AND CELL BIOLOGY
- Human NK Cells Selective Targeting of Colon Cancer-Initiating Cells: A Role for Natural Cytotoxicity Receptors and MHC Class I Molecules
- (2013) R. Tallerico et al. JOURNAL OF IMMUNOLOGY
- CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
- (2013) J Chu et al. LEUKEMIA
- Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells
- (2013) Hua Jiang et al. Molecular Oncology
- The Narrow-Spectrum HDAC Inhibitor Entinostat Enhances NKG2D Expression Without NK Cell Toxicity, Leading to Enhanced Recognition of Cancer Cells
- (2013) Shiguo Zhu et al. PHARMACEUTICAL RESEARCH
- Antigen Presenting Cell-Mediated Expansion of Human Umbilical Cord Blood Yields Log-Scale Expansion of Natural Killer Cells with Anti-Myeloma Activity
- (2013) Nina Shah et al. PLoS One
- Clinical-Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy
- (2013) David A. Knorr et al. Stem Cells Translational Medicine
- Engineering lymph node homing of ex vivo-expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7
- (2012) S. S. Somanchi et al. BLOOD
- Cytokine activation induces human memory-like NK cells
- (2012) R. Romee et al. BLOOD
- Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor
- (2012) Christiane Sahm et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Interleukin 2 in Cancer Therapy
- (2012) G. K. Antony et al. CURRENT MEDICINAL CHEMISTRY
- NK cell MHC class I specific receptors (KIR): from biology to clinical intervention
- (2012) Ariane Thielens et al. CURRENT OPINION IN IMMUNOLOGY
- A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies
- (2012) Noriko Shimasaki et al. CYTOTHERAPY
- Inhibition of Intracellular Antiviral Defense Mechanisms Augments Lentiviral Transduction of Human Natural Killer Cells: Implications for Gene Therapy
- (2012) Tolga Sutlu et al. HUMAN GENE THERAPY
- Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors
- (2012) Jing Ni et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Human Cytomegalovirus (CMV)-Induced Memory-like NKG2C+ NK Cells Are Transplantable and Expand In Vivo in Response to Recipient CMV Antigen
- (2012) B. Foley et al. JOURNAL OF IMMUNOLOGY
- Human microRNA-27a* targets Prf1 and GzmB expression to regulate NK-cell cytotoxicity
- (2011) T.-D. Kim et al. BLOOD
- Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function
- (2011) B. Foley et al. BLOOD
- Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor
- (2011) D V Tassev et al. CANCER GENE THERAPY
- Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression
- (2011) M. R. Parkhurst et al. CLINICAL CANCER RESEARCH
- Natural Killer Cells are Scarce in Colorectal Carcinoma Tissue Despite High Levels of Chemokines and Cytokines
- (2011) N. Halama et al. CLINICAL CANCER RESEARCH
- NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
- (2011) Ruth Esser et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Chemically defined conditions for human iPSC derivation and culture
- (2011) Guokai Chen et al. NATURE METHODS
- Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process
- (2011) Jan Spanholtz et al. PLoS One
- Innate or Adaptive Immunity? The Example of Natural Killer Cells
- (2011) E. Vivier et al. SCIENCE
- A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer
- (2010) Melissa A. Geller et al. CYTOTHERAPY
- Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy
- (2009) H. Fujisaki et al. CANCER RESEARCH
- Natural killer and γδ T cells in haematological malignancies: enhancing the immune effectors
- (2009) Jérôme Rey et al. TRENDS IN MOLECULAR MEDICINE
- Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation
- (2008) L. Vago et al. BLOOD
- Up on the tightrope: natural killer cell activation and inhibition
- (2008) Lewis L Lanier NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation