- Home
- Publications
- Publication Search
- Publication Details
Title
T Cell Subsets in Graft Versus Host Disease and Graft Versus Tumor
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-10-07
DOI
10.3389/fimmu.2021.761448
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Current Concepts and Advances in Graft-Versus-Host Disease Immunology
- (2021) Geoffrey R. Hill et al. Annual Review of Immunology
- A Phase 3 Double-Blind Study of the Addition of Tocilizumab versus Placebo to Cyclosporin/Methotrexate GvHD Prophylaxis
- (2021) Glen Kennedy et al. BLOOD
- Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8+ T cells drive gastrointestinal acute graft-versus-host disease
- (2021) Victor Tkachev et al. Science Translational Medicine
- The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
- (2021) Robert A. Saxton et al. IMMUNITY
- ROCK2 Inhibition With Belumosudil (KD025) for the Treatment of Chronic Graft-Versus-Host Disease
- (2021) Madan Jagasia et al. JOURNAL OF CLINICAL ONCOLOGY
- Belumosudil for Chronic Graft-versus-Host Disease (cGVHD) After 2 or More Prior Lines of Therapy: The ROCKstar Study
- (2021) Corey S Cutler et al. BLOOD
- Baricitinib prevents GvHD by increasing Tregs via JAK3 and treats established GvHD by promoting intestinal tissue repair via EGFR
- (2021) Sena Kim et al. LEUKEMIA
- Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease
- (2021) Robert Zeiser et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Phase 2 Study of F-652, a Novel Tissue-Targeted Recombinant Human Interleukin-22 (IL-22) Dimer, for Treatment of Newly Diagnosed Acute Gvhd of the Lower GI Tract
- (2020) Doris M. Ponce et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- The Emerging Landscape of Immune Cell Therapies
- (2020) Evan W. Weber et al. CELL
- Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease
- (2020) Robert Zeiser et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cellular therapies for graft-versus-host disease: a tale of tissue repair and tolerance
- (2020) Carlijn Voermans et al. BLOOD
- Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease
- (2020) Sherrie J. Divito et al. JOURNAL OF CLINICAL INVESTIGATION
- A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease
- (2020) Mark A. Schroeder et al. Blood Advances
- Tissue-resident PSGL1loCD4+ T cells promote B cell differentiation and chronic graft-versus-host disease–associated autoimmunity
- (2020) Xiaohui Kong et al. JOURNAL OF CLINICAL INVESTIGATION
- Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease
- (2020) Johanna Strobl et al. Science Translational Medicine
- Enhanced CAR-T activity against established tumors by polarizing human T cells to secrete interleukin-9
- (2020) Lintao Liu et al. Nature Communications
- Delivering cellular and gene therapies to patients: solutions for realizing the potential of the next generation of medicine
- (2019) Kris Elverum et al. GENE THERAPY
- Janus Kinase Inhibition for Graft-Versus-Host Disease: Current Status and Future Prospects
- (2019) Daniele Mannina et al. DRUGS
- The Role of Janus Kinase Signaling in Graft-Versus-Host Disease and Graft Versus Leukemia
- (2018) Mark A. Schroeder et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Immune regulatory cell infusion for graft-versus-host disease prevention and therapy
- (2018) Bruce R. Blazar et al. BLOOD
- Amphiregulin-Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis
- (2018) Yuki Morimoto et al. IMMUNITY
- Cholesterol negatively regulates IL-9–producing CD8+T cell differentiation and antitumor activity
- (2018) Xingzhe Ma et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Effector T Helper Cell Subsets in Inflammatory Bowel Diseases
- (2018) Tanbeena Imam et al. Frontiers in Immunology
- Transient T-bet expression functionally specifies a distinct T follicular helper subset
- (2018) Difeng Fang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Specifically differentiated T cell subset promotes tumor immunity over fatal immunity
- (2017) Abdulraouf Ramadan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity
- (2017) Maximilian W. Plank et al. JOURNAL OF IMMUNOLOGY
- Natalizumab-associated PML
- (2017) Nicholas Schwab et al. NEUROLOGY
- Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy
- (2017) Robert Zeiser et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites
- (2017) Brahma V. Kumar et al. Cell Reports
- The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases
- (2017) Brad Griesenauer et al. Frontiers in Immunology
- Circulating T follicular helper cells with increased function during chronic graft-versus-host disease
- (2016) E. Forcade et al. BLOOD
- Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
- (2016) R. Flynn et al. BLOOD
- Chronic graft-versus-host disease: biological insights from preclinical and clinical studies
- (2016) Kelli P. A. MacDonald et al. BLOOD
- A phase 3 randomized trial comparing inolimomab vs usual care in steroid-resistant acute GVHD
- (2016) Gérard Socié et al. BLOOD
- Alloantigen presentation and graft-versus-host disease: fuel for the fire
- (2016) M. Koyama et al. BLOOD
- Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation
- (2016) Robert Zeiser et al. BRITISH JOURNAL OF HAEMATOLOGY
- Advances in understanding the pathogenesis of graft-versus-host disease
- (2016) John Magenau et al. BRITISH JOURNAL OF HAEMATOLOGY
- CD4+T-cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm
- (2016) Kiyoshi Hirahara et al. INTERNATIONAL IMMUNOLOGY
- Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor
- (2016) Katherine G. MacDonald et al. JOURNAL OF CLINICAL INVESTIGATION
- Biomarker Panel for Chronic Graft-Versus-Host Disease
- (2016) Jeffrey Yu et al. JOURNAL OF CLINICAL ONCOLOGY
- Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion
- (2016) Martin Chopra et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Role of memory T cell subsets for adoptive immunotherapy
- (2016) Dirk H. Busch et al. SEMINARS IN IMMUNOLOGY
- Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect
- (2015) C. G. Brunstein et al. BLOOD
- A Distinct Function of Regulatory T Cells in Tissue Protection
- (2015) Nicholas Arpaia et al. CELL
- Type 1 regulatory T cells: a new mechanism of peripheral immune tolerance
- (2015) Hanyu Zeng et al. Cellular & Molecular Immunology
- Outcomes of acute leukemia patients transplanted with naive T cell–depleted stem cell grafts
- (2015) Marie Bleakley et al. JOURNAL OF CLINICAL INVESTIGATION
- Cytokines in Graft-versus-Host Disease
- (2015) Andrea S. Henden et al. JOURNAL OF IMMUNOLOGY
- Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey
- (2015) R Zeiser et al. LEUKEMIA
- ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease
- (2015) Jilu Zhang et al. Science Translational Medicine
- Various Forms of Tissue Damage and Danger Signals Following Hematopoietic Stem-Cell Transplantation
- (2015) Abdulraouf Ramadan et al. Frontiers in Immunology
- Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease
- (2014) S. Spoerl et al. BLOOD
- Vedolizumab for ulcerative colitis and Crohn's disease: results and implications of GEMINI studies
- (2014) Mindy CW Lam et al. Immunotherapy
- Ibrutinib treatment ameliorates murine chronic graft-versus-host disease
- (2014) Jason A. Dubovsky et al. JOURNAL OF CLINICAL INVESTIGATION
- T-bet Is Critical for the Development of Acute Graft-versus-Host Disease through Controlling T Cell Differentiation and Function
- (2014) Jianing Fu et al. JOURNAL OF IMMUNOLOGY
- Differential Requirement for IL-2 and IL-15 during Bifurcated Development of Thymic Regulatory T Cells
- (2014) Daniel Marshall et al. JOURNAL OF IMMUNOLOGY
- Interleukin-22 Aggravates Murine Acute Graft-Versus-Host Disease by Expanding Effector T Cell and Reducing Regulatory T Cell
- (2014) Kai Zhao et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial
- (2014) Glen A Kennedy et al. LANCET ONCOLOGY
- Pharmacologic Blockade of JAK1/JAK2 Reduces GvHD and Preserves the Graft-Versus-Leukemia Effect
- (2014) Jaebok Choi et al. PLoS One
- Tumor-specific IL-9–producing CD8+Tc9 cells are superior effector than type-I cytotoxic Tc1 cells for adoptive immunotherapy of cancers
- (2014) Yong Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells
- (2014) Rosa Bacchetta et al. Frontiers in Immunology
- The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo
- (2013) A. Heine et al. BLOOD
- Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation
- (2013) D. H. Fowler et al. BLOOD
- Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease
- (2013) M.-C. Bruggen et al. BLOOD
- Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
- (2013) J. A. Dubovsky et al. BLOOD
- The Interleukin-1 Family: Back to the Future
- (2013) Cecilia Garlanda et al. IMMUNITY
- The identification and characteristics of IL-22-producing T cells in acute graft-versus-host disease following allogeneic bone marrow transplantation
- (2013) Kai Zhao et al. IMMUNOBIOLOGY
- Cutting Edge: STAT1 Is Required for IL-6-Mediated Bcl6 Induction for Early Follicular Helper Cell Differentiation
- (2013) Y. S. Choi et al. JOURNAL OF IMMUNOLOGY
- Vedolizumab, a monoclonal antibody to the gut homing α4β7 integrin, does not affect cerebrospinal fluid T-lymphocyte immunophenotype
- (2013) Catherine Milch et al. JOURNAL OF NEUROIMMUNOLOGY
- IL-22 deficiency in donor T cells attenuates murine acute graft-versus-host disease mortality while sparing the graft-versus-leukemia effect
- (2013) M Couturier et al. LEUKEMIA
- ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death
- (2013) Mark T. Vander Lugt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Rapamycin Resistant Murine Th9 Cells Have a Stable In Vivo Phenotype and Inhibit Graft-Versus-Host Reactivity
- (2013) Courtney W. Mangus et al. PLoS One
- Expression of CD30 in patients with acute graft-versus-host disease
- (2012) Y.-B. Chen et al. BLOOD
- The interferon-dependent orchestration of innate and adaptive immunity after transplantation
- (2012) R. J. Robb et al. BLOOD
- IFN R signaling mediates alloreactive T-cell trafficking and GVHD
- (2012) J. Choi et al. BLOOD
- Tc9 cells, a new subset of CD8+T cells, support Th2-mediated airway inflammation
- (2012) Alexander Visekruna et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
- (2012) Alan M. Hanash et al. IMMUNITY
- Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
- (2012) André Ballesteros-Tato et al. IMMUNITY
- Th9 cells promote antitumor immune responses in vivo
- (2012) Yong Lu et al. JOURNAL OF CLINICAL INVESTIGATION
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-21 Promotes Lupus-like Disease in Chronic Graft-versus-Host Disease through Both CD4 T Cell- and B Cell-Intrinsic Mechanisms
- (2012) V. Nguyen et al. JOURNAL OF IMMUNOLOGY
- Attenuation of Acute Graft-versus-Host Disease in the Absence of the Transcription Factor ROR t
- (2012) L. M. Fulton et al. JOURNAL OF IMMUNOLOGY
- Robust tumor immunity to melanoma mediated by interleukin-9–producing T cells
- (2012) Rahul Purwar et al. NATURE MEDICINE
- Peripheral-Blood Stem Cells versus Bone Marrow from Unrelated Donors
- (2012) Claudio Anasetti et al. NEW ENGLAND JOURNAL OF MEDICINE
- Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution
- (2011) N. Li et al. BLOOD
- Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and ROR t in mice
- (2011) Y. Yu et al. BLOOD
- Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL
- (2011) A. M. Hanash et al. BLOOD
- Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen
- (2011) B. C. Betts et al. BLOOD
- Induction of acute GVHD by sex-mismatched H-Y antigens in the absence of functional radiosensitive host hematopoietic-derived antigen-presenting cells
- (2011) T. Toubai et al. BLOOD
- Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells
- (2011) H.-J. Shin et al. BLOOD
- Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
- (2011) M. Di Ianni et al. BLOOD
- Lack of IL-21 signal attenuates graft-versus-leukemia effect in the absence of CD8 T-cells
- (2011) A Meguro et al. BONE MARROW TRANSPLANTATION
- Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells
- (2011) Marion Pepper et al. IMMUNITY
- ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6
- (2011) Youn Soo Choi et al. IMMUNITY
- Cutting Edge: Dendritic Cell-Restricted Antigen Presentation Initiates the Follicular Helper T Cell Program but Cannot Complete Ultimate Effector Differentiation
- (2011) R. Goenka et al. JOURNAL OF IMMUNOLOGY
- Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease
- (2011) Motoko Koyama et al. NATURE MEDICINE
- IL-33 Induces IL-9 Production in Human CD4+ T Cells and Basophils
- (2011) Lars Blom et al. PLoS One
- Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity
- (2011) K. L. Hippen et al. Science Translational Medicine
- Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells
- (2010) M. Bleakley et al. BLOOD
- Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses
- (2010) R. Das et al. BLOOD
- Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics
- (2010) C. G. Brunstein et al. BLOOD
- Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma
- (2010) G. R. Hill et al. BLOOD
- Understanding the development and function of T follicular helper cells
- (2010) Roza I Nurieva et al. Cellular & Molecular Immunology
- Interleukin-6 Modulates Graft-versus-Host Responses after Experimental Allogeneic Bone Marrow Transplantation
- (2010) I. Tawara et al. CLINICAL CANCER RESEARCH
- Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo
- (2010) Vandana Kalia et al. IMMUNITY
- Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells
- (2010) Matthew E. Pipkin et al. IMMUNITY
- The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
- (2010) Hua-Chen Chang et al. NATURE IMMUNOLOGY
- T helper17 Cells Are Sufficient But Not Necessary to Induce Acute Graft-Versus-Host Disease
- (2009) Cristina Iclozan et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation
- (2009) C. Bucher et al. BLOOD
- Comprehensive assessment of T-cell receptor -chain diversity in T cells
- (2009) H. S. Robins et al. BLOOD
- Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease
- (2009) T. Yi et al. BLOOD
- Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease
- (2009) X. Chen et al. BLOOD
- Absence of IL-23p19 in donor allogeneic cells reduces mortality from acute GVHD
- (2009) J S Thompson et al. BONE MARROW TRANSPLANTATION
- IL-21 is critical for GVHD in a mouse model
- (2009) A Meguro et al. BONE MARROW TRANSPLANTATION
- A Th17-like developmental process leads to CD8+Tc17 cells with reduced cytotoxic activity
- (2009) Magdalena Huber et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
- (2009) Stefanie Eyerich et al. JOURNAL OF CLINICAL INVESTIGATION
- Central Memory CD8 + T Cells Induce Graft-versus-Host Disease and Mediate Graft-versus-Leukemia
- (2009) Hong Zheng et al. JOURNAL OF IMMUNOLOGY
- The Binding Specificity and Selective Antagonism of Vedolizumab, an Anti- 4 7 Integrin Therapeutic Antibody in Development for Inflammatory Bowel Diseases
- (2009) D. Soler et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Bcl6 Mediates the Development of T Follicular Helper Cells
- (2009) R. I. Nurieva et al. SCIENCE
- Interleukin-17–Producing T-Helper Cells as New Potential Player Mediating Graft-Versus-Host Disease in Patients Undergoing Allogeneic Stem-Cell Transplantation
- (2009) Erica Dander et al. TRANSPLANTATION
- Interleukin-23 secretion by donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-host disease
- (2008) R. Das et al. BLOOD
- Graft rejection as a Th1-type process amenable to regulation by donor Th2-type cells through an interleukin-4/STAT6 pathway
- (2008) J. Mariotti et al. BLOOD
- In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations
- (2008) M. J. Carlson et al. BLOOD
- The effects of IL-6 on CD4 T cell responses
- (2008) Oliver Dienz et al. CLINICAL IMMUNOLOGY
- Combined Th2 cytokine deficiency in donor T cells aggravates experimental acute graft-vs-host disease
- (2008) Isao Tawara et al. EXPERIMENTAL HEMATOLOGY
- IL-21 and TGF-β are required for differentiation of human TH17 cells
- (2008) Li Yang et al. NATURE
- Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset
- (2008) Marc Veldhoen et al. NATURE IMMUNOLOGY
- IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells
- (2008) Valérie Dardalhon et al. NATURE IMMUNOLOGY
- A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
- (2008) Yongzhong Liu et al. NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation