B-Cell Dysregulation in Idiopathic Nephrotic Syndrome: What We Know and What We Need to Discover

The Effect of Interleukin-4 and Dexamethasone on RNA-Seq-Based Transcriptomic Profiling of Human Podocytes: A Potential Role in Minimal Change Nephrotic Syndrome

(2021) Jiwon M. Lee et al.   Journal of Clinical Medicine

Human or Chimeric Monoclonal Anti-CD20 Antibodies for Children with Nephrotic Syndrome: A Superiority Randomized Trial

(2021) Pietro Ravani et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A mouse model of prenatal exposure to Interleukin-6 to study the developmental origin of health and disease

(2021) Tarak Srivastava et al.   Scientific Reports

CyTOF-Enabled Analysis Identifies Class-Switched B Cells as the Main Lymphocyte Subset Associated With Disease Relapse in Children With Idiopathic Nephrotic Syndrome

(2021) Miguel Fribourg et al.   Frontiers in Immunology

Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology

(2021) Andrew J.B. Watts et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Circulating plasmablasts in children with steroid-sensitive nephrotic syndrome

(2021) Federica Zotta et al.   PEDIATRIC NEPHROLOGY

B Lymphocyte Subsets in Children With Steroid-Sensitive Nephrotic Syndrome: A Longitudinal Study

(2021) Chen Ling et al.   Frontiers in Pediatrics

Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome

(2020) Xiaoyuan Jia et al.   KIDNEY INTERNATIONAL

Novel insights in the genetics of steroid-sensitive nephrotic syndrome in childhood

(2020) Stephanie Dufek-Kamperis et al.   PEDIATRIC NEPHROLOGY

Circulating plasmablasts and high level of BAFF are hallmarks of minimal change nephrotic syndrome in adults

(2020) Julie Oniszczuk et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

B Cell Responses: Cell Interaction Dynamics and Decisions

(2019) Jason G. Cyster et al.   CELL

Atypical IgM on T cells predict relapse and steroid-dependence in idiopathic nephrotic syndrome

(2019) Manuela Colucci et al.   KIDNEY INTERNATIONAL

Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome

(2019) Stephanie Dufek et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Both the rituximab dose and maintenance immunosuppression in steroid-dependent/frequently-relapsing nephrotic syndrome have important effects on outcomes

(2019) Eugene Yu-hin Chan et al.   KIDNEY INTERNATIONAL

Circulating follicular T helper cells are possibly associated with low levels of serum immunoglobulin G due to impaired immunoglobulin class-switch recombination of B cells in children with primary nephrotic syndrome

(2019) Xia Yang et al.   MOLECULAR IMMUNOLOGY

A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

(2019) Astgik Petrosyan et al.   Nature Communications

Altered B-Lymphocyte Homeostasis in Idiopathic Nephrotic Syndrome

(2019) Chen Ling et al.   Frontiers in Pediatrics

Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood

(2018) Elena Blanco et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NEPHRUTIX: A randomized, double-blind, placebo vs Rituximab-controlled trial assessing T-cell subset changes in Minimal Change Nephrotic Syndrome

(2018) Ahmed Boumediene et al.   JOURNAL OF AUTOIMMUNITY

Autoantibodies against podocytic UCHL1 are associated with idiopathic nephrotic syndrome relapses and induce proteinuria in mice

(2018) Agnès Jamin et al.   JOURNAL OF AUTOIMMUNITY

Targeting B Cells and Plasma Cells in Glomerular Diseases: Translational Perspectives

(2018) Eva Schrezenmeier et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome

(2018) Hanna Debiec et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Idiopathic nephrotic syndrome in children

(2018) Damien G Noone et al.   LANCET

Rituximab modulates T- and B-lymphocyte subsets and urinary CD80 excretion in patients with steroid-dependent nephrotic syndrome

(2018) Divya Bhatia et al.   PEDIATRIC RESEARCH

B cell phenotype in pediatric idiopathic nephrotic syndrome

(2018) Manuela Colucci et al.   PEDIATRIC NEPHROLOGY

An open-label randomized controlled trial of low-dose corticosteroid plus enteric-coated mycophenolate sodium versus standard corticosteroid treatment for minimal change nephrotic syndrome in adults (MSN Study)

(2018) Philippe Rémy et al.   KIDNEY INTERNATIONAL

Effector and regulatory B cells in immune-mediated kidney disease

(2018) Kristine Oleinika et al.   Nature Reviews Nephrology

Immunology of idiopathic nephrotic syndrome

(2017) Manuela Colucci et al.   PEDIATRIC NEPHROLOGY

Minimal Change Disease

(2016) Marina Vivarelli et al.   Clinical Journal of the American Society of Nephrology

Minimal change disease and idiopathic FSGS: manifestations of the same disease

(2016) Rutger J. Maas et al.   Nature Reviews Nephrology

Idiopathic nephrotic syndrome: the EBV hypothesis

(2016) Claire Dossier et al.   PEDIATRIC RESEARCH

B Cells, Antibodies, and More

(2015) W. Hoffman et al.   Clinical Journal of the American Society of Nephrology

Anti-CD20 Antibodies for Idiopathic Nephrotic Syndrome in Children

(2015) P. Ravani et al.   Clinical Journal of the American Society of Nephrology

B Cell Reconstitution after Rituximab Treatment in Idiopathic Nephrotic Syndrome

(2015) M. Colucci et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The glomerular permeability factors in idiopathic nephrotic syndrome

(2015) Jean-Claude Davin   PEDIATRIC NEPHROLOGY

HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome

(2014) R. A. Gbadegesin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicentre, double-blind, randomised, placebo-controlled trial

(2014) Kazumoto Iijima et al.   LANCET

Minimal Change Nephrotic Syndrome Associated With Non-Hodgkin Lymphoid Disorders

(2014) Tomek Kofman et al.   MEDICINE

A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation

(2014) M. Delville et al.   Science Translational Medicine

IgM Contributes to Glomerular Injury in FSGS

(2013) D. Strassheim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis

(2011) Henner Morbach et al.   ARTHRITIS AND RHEUMATISM

Occurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes

(2010) V. Audard et al.   BLOOD

Characterisation of renal immune cell infiltrates in children with nephrotic syndrome

(2010) Kerstin Benz et al.   PEDIATRIC NEPHROLOGY

Idiopathic Nephrotic Syndrome and Atopy: Is There a Common Link?

(2009) Maher Abdel-Hafez et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Stem cell mobilization in idiopathic steroid-sensitive nephrotic syndrome

(2008) Hélène Lapillonne et al.   PEDIATRIC NEPHROLOGY