Circulating plasmablasts and high level of BAFF are hallmarks of minimal change nephrotic syndrome in adults

LB001EFFICACY AND SAFETY OF BELIMUMAB IN PATIENTS WITH ACTIVE LUPUS NEPHRITIS: A PHASE 3, RANDOMISED, PLACEBO-CONTROLLED TRIAL

(2020) Brad Rovin et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Atypical IgM on T cells predict relapse and steroid-dependence in idiopathic nephrotic syndrome

(2019) Manuela Colucci et al.   KIDNEY INTERNATIONAL

Pediatric Patients With Steroid-Sensitive Nephrotic Syndrome Have Higher Expression of T Regulatory Lymphocytes in Comparison to Steroid-Resistant Disease

(2019) Fabio Tadeu Lourenço Guimarães et al.   Frontiers in Pediatrics

Class-Switch Recombination Occurs Infrequently in Germinal Centers

(2019) Jonathan A. Roco et al.   IMMUNITY

Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome

(2019) Manuela Colucci et al.   Frontiers in Immunology

CMIP is a negative regulator of T cell signaling

(2019) Julie Oniszczuk et al.   Cellular & Molecular Immunology

Circulating follicular T helper cells are possibly associated with low levels of serum immunoglobulin G due to impaired immunoglobulin class-switch recombination of B cells in children with primary nephrotic syndrome

(2019) Xia Yang et al.   MOLECULAR IMMUNOLOGY

Altered B-Lymphocyte Homeostasis in Idiopathic Nephrotic Syndrome

(2019) Chen Ling et al.   Frontiers in Pediatrics

NEPHRUTIX: A randomized, double-blind, placebo vs Rituximab-controlled trial assessing T-cell subset changes in Minimal Change Nephrotic Syndrome

(2018) Ahmed Boumediene et al.   JOURNAL OF AUTOIMMUNITY

Autoantibodies against podocytic UCHL1 are associated with idiopathic nephrotic syndrome relapses and induce proteinuria in mice

(2018) Agnès Jamin et al.   JOURNAL OF AUTOIMMUNITY

Increased PD-1 + CD154 + Tfh cells are possibly the most important functional subset of PD-1 + T follicular helper cells in adult patients with minimal change disease

(2018) Tao Li et al.   MOLECULAR IMMUNOLOGY

B cell phenotype in pediatric idiopathic nephrotic syndrome

(2018) Manuela Colucci et al.   PEDIATRIC NEPHROLOGY

An open-label randomized controlled trial of low-dose corticosteroid plus enteric-coated mycophenolate sodium versus standard corticosteroid treatment for minimal change nephrotic syndrome in adults (MSN Study)

(2018) Philippe Rémy et al.   KIDNEY INTERNATIONAL

BAFF and BAFF-Receptor in B Cell Selection and Survival

(2018) Cristian R. Smulski et al.   Frontiers in Immunology

B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity

(2017) Tanvi Arkatkar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B- and T-cell subpopulations in patients with severe idiopathic membranous nephropathy may predict an early response to rituximab

(2017) Michelle Rosenzwajg et al.   KIDNEY INTERNATIONAL

Immunology of idiopathic nephrotic syndrome

(2017) Manuela Colucci et al.   PEDIATRIC NEPHROLOGY

Minimal Change Disease

(2016) Marina Vivarelli et al.   Clinical Journal of the American Society of Nephrology

Dances with cytokines, featuring TFH cells, IL-21, IL-4 and B cells

(2016) Simon Bélanger et al.   NATURE IMMUNOLOGY

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

(2016) Martina Minnich et al.   NATURE IMMUNOLOGY

The BAFFling effects of rituximab in lupus: danger ahead?

(2016) Michael R. Ehrenstein et al.   Nature Reviews Rheumatology

Regulatory T cells and minimal change nephropathy: in the midst of a complex network

(2015) R. Bertelli et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Anti-CD20 Antibodies for Idiopathic Nephrotic Syndrome in Children

(2015) P. Ravani et al.   Clinical Journal of the American Society of Nephrology

B Cell Reconstitution after Rituximab Treatment in Idiopathic Nephrotic Syndrome

(2015) M. Colucci et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pathophysiological advances in membranous nephropathy: time for a shift in patient's care

(2015) Pierre Ronco et al.   LANCET

Rituximab for childhood-onset, complicated, frequently relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicentre, double-blind, randomised, placebo-controlled trial

(2014) Kazumoto Iijima et al.   LANCET

IL-6 supports the generation of human long-lived plasma cells in combination with either APRIL or stromal cell-soluble factors

(2014) M Jourdan et al.   LEUKEMIA

Minimal Change Nephrotic Syndrome Associated With Non-Hodgkin Lymphoid Disorders

(2014) Tomek Kofman et al.   MEDICINE

Permeability factors in idiopathic nephrotic syndrome: historical perspectives and lessons for the future

(2014) Rutger J. Maas et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Immunopathogenesis of membranous nephropathy: an update

(2014) Hanna Debiec et al.   Seminars in Immunopathology

Immunopathogenesis of idiopathic nephrotic syndrome with relapse

(2014) Djillali Sahali et al.   Seminars in Immunopathology

A New Equation to Estimate Glomerular Filtration Rate

(2013) Andrew S. Levey et al.   ANNALS OF INTERNAL MEDICINE

The Treatment of Minimal Change Disease in Adults

(2013) J. Hogan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rituximab is an efficient and safe treatment in adults with steroid-dependent minimal change disease

(2013) Helene Munyentwali et al.   KIDNEY INTERNATIONAL

Rituximab for minimal change disease in adults: long-term follow-up

(2013) A. Bruchfeld et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Th17/Treg imbalance in adult patients with minimal change nephrotic syndrome

(2011) Li-li Liu et al.   CLINICAL IMMUNOLOGY

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Occurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes

(2010) V. Audard et al.   BLOOD

HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus

(2009) A M Jacobi et al.   ANNALS OF THE RHEUMATIC DISEASES

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

Stem cell mobilization in idiopathic steroid-sensitive nephrotic syndrome

(2008) Hélène Lapillonne et al.   PEDIATRIC NEPHROLOGY