Depth filtration in bioprocessing — new opportunities for an old technology

Virus pH‐Dependent Interactions with Cationically Modified Cellulose and Their Application in Water Filtration

(2021) Samuel Watts et al.   Small

Pretreatments for enhancing clarification efficiency of depth filtration during production of monoclonal antibody therapeutics

(2020) Sandeep R. Hadpe et al.   BIOTECHNOLOGY PROGRESS

Effectiveness of Host Cell Protein Removal using Depth Filtration with a Filter Containing Diatomaceous Earth

(2020) Negin Nejatishahidein et al.   BIOTECHNOLOGY PROGRESS

Moving from the bench towards a large scale, industrial platform process for adeno‐associated viral vector purification

(2020) Benjamin Adams et al.   BIOTECHNOLOGY AND BIOENGINEERING

Automation of Dead End Filtration: An Enabler for Continuous Processing of Biotherapeutics

(2020) Garima Thakur et al.   Frontiers in Bioengineering and Biotechnology

Intensified Downstream Processing of Monoclonal Antibodies Using Membrane Technology

(2020) Sathish Nadar et al.   Biotechnology Journal

Control of leached beta‐glucan levels from depth filters by an improved depth filtration flush strategy

(2020) Melissa Holstein et al.   BIOTECHNOLOGY PROGRESS

Improving viral filtration capacity in biomanufacturing processes using aggregate binding properties of polyamide‐6,6

(2020) Vitali Stanevich et al.   BIOTECHNOLOGY AND BIOENGINEERING

A new simplified clarification approach for lentiviral vectors using diatomaceous earth improves throughput and safe handling

(2020) Jennifer J. Labisch et al.   JOURNAL OF BIOTECHNOLOGY

Flow and residence time distribution in small-scale dual-layer depth filter capsules

(2020) Minyoung Kim et al.   JOURNAL OF MEMBRANE SCIENCE

Investigation of fouling mechanisms of virus filters during the filtration of protein solutions using a high throughput filtration screening device

(2019) Marc Bieberbach et al.   BIOTECHNOLOGY PROGRESS

Control of antibody high and low molecular weight species by depth filtration based cell culture harvesting

(2019) Deqiang Yu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Efficient filtration strategies for the clarification of influenza virus-like particles derived from insect cells

(2019) Sofia B. Carvalho et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Process intensification by frontal chromatography: Performance comparison of resin and membrane adsorber for monovalent antibody aggregate removal

(2019) Sebastian Vogg et al.   BIOTECHNOLOGY AND BIOENGINEERING

Adsorptive filtration: A case study for early impurity reduction in an Escherichia coli production process

(2019) Karl F.J. Metzger et al.   BIOTECHNOLOGY PROGRESS

Contributions of depth filter components to protein adsorption in bioprocessing

(2018) Ohnmar Khanal et al.   BIOTECHNOLOGY AND BIOENGINEERING

Improved HCP Reduction Using a New, All-Synthetic Depth Filtration Media Within an Antibody Purification Process

(2018) Hoang C. Nguyen et al.   Biotechnology Journal

Improved HCP Reduction Using a New, All-Synthetic Depth Filtration Media Within an Antibody Purification Process

(2018) Hoang C. Nguyen et al.   Biotechnology Journal

DNA retention on depth filters

(2018) Ohnmar Khanal et al.   JOURNAL OF MEMBRANE SCIENCE

Continuous cell flocculation for recombinant antibody harvesting

(2017) Daniel Burgstaller et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Development of adsorptive hybrid filters to enable two-step purification of biologics

(2016) Nripen Singh et al.   mAbs

Mechanistic evaluation of virus clearance by depth filtration

(2015) Adith Venkiteshwaran et al.   BIOTECHNOLOGY PROGRESS

Clarification of recombinant proteins from high cell density mammalian cell culture systems using new improved depth filters

(2013) Nripen Singh et al.   BIOTECHNOLOGY AND BIOENGINEERING