Adsorptive filtration: A case study for early impurity reduction in an Escherichia coli production process

A fast and simple approach to optimize the unit operation high pressure homogenization - a case study for a soluble therapeutic protein in E. coli

(2019) Alexander Pekarsky et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

PolyBall: A new adsorbent for the efficient removal of endotoxin from biopharmaceuticals

(2019) Sidharth Razdan et al.   Scientific Reports

A two-step process for capture and purification of human basic fibroblast growth factor from E. coli homogenate: Yield versus endotoxin clearance

(2018) Dominik Georg Sauer et al.   PROTEIN EXPRESSION AND PURIFICATION

A combination of HPLC and automated data analysis for monitoring the efficiency of high-pressure homogenization

(2017) Britta Eggenreich et al.   Microbial Cell Factories

DoE based integration approach of upstream and downstream processing regarding HCP and ATPE as harvest operation

(2016) Petra Gronemeyer et al.   BIOCHEMICAL ENGINEERING JOURNAL

Development of adsorptive hybrid filters to enable two-step purification of biologics

(2016) Nripen Singh et al.   mAbs

Clarification technologies for monoclonal antibody manufacturing processes: Current state and future perspectives

(2015) Nripen Singh et al.   BIOTECHNOLOGY AND BIOENGINEERING

Understanding Nucleic Acid–Ion Interactions

(2014) Jan Lipfert et al.   Annual Review of Biochemistry

Removal of Lipopolysaccharide and DNA from Protein Solutions Using Porous Supports Bearing Polymeric Lipid Membranes

(2014) Masa-aki Wakita   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Clarification of recombinant proteins from high cell density mammalian cell culture systems using new improved depth filters

(2013) Nripen Singh et al.   BIOTECHNOLOGY AND BIOENGINEERING

A Comparative Analysis of Industrial Escherichia coli K–12 and B Strains in High-Glucose Batch Cultivations on Process-, Transcriptome- and Proteome Level

(2013) Karoline Marisch et al.   PLoS One

Cytoplasmic pH Response to Acid Stress in Individual Cells of Escherichia coli and Bacillus subtilis Observed by Fluorescence Ratio Imaging Microscopy

(2012) Keith A. Martinez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Anion exchange membrane adsorbers for flow-through polishing steps: Part I. clearance of minute virus of mice

(2012) Justin Weaver et al.   BIOTECHNOLOGY AND BIOENGINEERING

Endotoxin removal and prevention for pre-clinical biologics production

(2012) Anne Serdakowski London et al.   Biotechnology Journal

A novel primary amine-based anion exchange membrane adsorber

(2011) Maybelle Woo et al.   JOURNAL OF CHROMATOGRAPHY A

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Downstream of downstream processing - Integrated bioprocess development from upstream to downstream

(2009) F. Grote et al.   CHEMIE INGENIEUR TECHNIK

Evaluation of the impact of lipid fouling during the chromatographic purification of virus-like particles fromSaccharomyces cerevisiae

(2009) Jing Jin et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Capture and release of genomic DNA by PEI modified Fe 3 O 4 /Au nanoparticles

(2009) Hanwen Sun et al.   Materials Science & Engineering C-Materials for Biological Applications

Microbial factories for recombinant pharmaceuticals

(2009) Neus Ferrer-Miralles et al.   Microbial Cell Factories

Impact of clarification strategy on chromatographic separations: Pre-processing of cell homogenates

(2008) D.G. Bracewell et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein production and purification

(2008) Susanne Gräslund et al.   NATURE METHODS

High-level expression, purification, and characterization of recombinant human basic fibroblast growth factor in Pichia pastoris

(2008) Xupeng Mu et al.   PROTEIN EXPRESSION AND PURIFICATION