Small Extracellular Vesicles Propagate the Inflammatory Response After Trauma

The effect of rural hospital closures on emergency medical service response and transport times

(2020) Katherine E. M. Miller et al.   HEALTH SERVICES RESEARCH

The Effects of IL-1β on Astrocytes are Conveyed by Extracellular Vesicles and Influenced by Age

(2020) Cory M. Willis et al.   NEUROCHEMICAL RESEARCH

Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice

(2020) Milena Armacki et al.   GASTROENTEROLOGY

Sorting Mechanisms for MicroRNAs into Extracellular Vesicles and Their Associated Diseases

(2020) Michael Groot et al.   Cells

Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α

(2020) Fatema Al-Rashed et al.   Scientific Reports

Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung

(2019) Kristopher R. Genschmer et al.   CELL

CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3

(2019) Sagar Paudel et al.   BLOOD

Role and Molecular Mechanisms of Pericytes in Regulation of Leukocyte Diapedesis in Inflamed Tissues

(2019) Paulina Rudziak et al.   MEDIATORS OF INFLAMMATION

HMGB1/RAGE pro-inflammatory axis promotes vascular endothelial cell apoptosis in limb ischemia/reperfusion injury

(2019) Lei Mi et al.   BIOMEDICINE & PHARMACOTHERAPY

Damage-associated molecular patterns in trauma

(2019) Borna Relja et al.   European Journal of Trauma and Emergency Surgery

Transcription factor Fra-2 and its emerging role in matrix deposition, proliferation and inflammation in chronic lung diseases

(2019) A. Birnhuber et al.   CELLULAR SIGNALLING

Effects of sodium thiosulfate (Na2S2O3) during resuscitation from hemorrhagic shock in swine with preexisting atherosclerosis

(2019) Thomas Datzmann et al.   PHARMACOLOGICAL RESEARCH

MicroRNA-298 represses hepatocellular carcinoma progression by inhibiting CTNND1-mediated Wnt/β-catenin signaling

(2018) Ningjia Cao et al.   BIOMEDICINE & PHARMACOTHERAPY

PKD regulates actin polymerization, neutrophil deformability, and transendothelial migration in response to fMLP and trauma

(2018) Christoph Wille et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of RNA-binding proteins in exosomes capable of interacting with different types of RNA: RBP-facilitated transport of RNAs into exosomes

(2018) Luisa Statello et al.   PLoS One

Role of Hemorrhagic Shock in Experimental Polytrauma

(2018) Stephanie Denk et al.   SHOCK

Extracellular Vesicles as Markers and Mediators in Sepsis

(2018) Pierre Raeven et al.   Theranostics

S100A8/A9 in Inflammation

(2018) Siwen Wang et al.   Frontiers in Immunology

Neutral Sphingomyelinase Inhibition Alleviates LPS Induced Microglia Activation and Neuroinflammation after Experimental Traumatic Brain Injury

(2018) Asit Kumar et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury

(2018) Roya Sharifian et al.   Scientific Reports

Overview of the IL-1 family in innate inflammation and acquired immunity

(2017) Charles A. Dinarello   IMMUNOLOGICAL REVIEWS

Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli

(2017) Margaret Alexander et al.   JOURNAL OF IMMUNOLOGY

Regulation of endothelial barrier function by p120-catenin∙VE-cadherin interaction

(2017) Joshua P. Garrett et al.   MOLECULAR BIOLOGY OF THE CELL

Contemporary Patterns of Multiple Organ Dysfunction in Trauma

(2017) Joanna M. Shepherd et al.   SHOCK

MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

(2017) Yun Teng et al.   Nature Communications

Changes in the pattern of plasma extracellular vesicles after severe trauma

(2017) Sahithi J. Kuravi et al.   PLoS One

Regulation of pulmonary endothelial barrier function by kinases

(2016) Nektarios Barabutis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Emerging role of chemokine CC motif ligand 4 related mechanisms in diabetes mellitus and cardiovascular disease: friends or foes?

(2016) Ting-Ting Chang et al.   Cardiovascular Diabetology

Inhibition of Aberrant MicroRNA-133a Expression in Endothelial Cells by Statin Prevents Endothelial Dysfunction by Targeting GTP Cyclohydrolase 1 in VivoClinical Perspective

(2016) Peng Li et al.   CIRCULATION

Luminal Extracellular Vesicles (EVs) in Inflammatory Bowel Disease (IBD) Exhibit Proinflammatory Effects on Epithelial Cells and Macrophages

(2016) Shuji Mitsuhashi et al.   INFLAMMATORY BOWEL DISEASES

CD68/macrosialin: not just a histochemical marker

(2016) Dimitry A Chistiakov et al.   LABORATORY INVESTIGATION

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Whereʼs the Leak in Vascular Barriers? A Review

(2016) Melissa A. Kottke et al.   SHOCK

THE GLYCOCALYX AND TRAUMA

(2016) Andreia Z. Chignalia et al.   SHOCK

Evidence for chemokine synergy during neutrophil migration in ARDS

(2016) Andrew E Williams et al.   THORAX

Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction

(2015) Kobina Essandoh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5

(2015) Yin-Sha Miao et al.   CELLULAR SIGNALLING

Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion

(2015) Tim Eiseler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

(2015) Elaheh Rahbar et al.   Journal of Translational Medicine

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Lung epithelial cell-derived extracellular vesicles activate macrophage-mediated inflammatory responses via ROCK1 pathway

(2015) H-G Moon et al.   Cell Death & Disease

Crucial Role of IL1beta and C3a in the In Vitro-Response of Multipotent Mesenchymal Stromal Cells to Inflammatory Mediators of Polytrauma

(2015) Nina-Emily Hengartner et al.   PLoS One

Inflammatory response to trauma

(2014) Albert Pierce et al.   Current Opinion in Anesthesiology

Cytokine Levels (IL-4, IL-6, IL-8 and TGFβ) as Potential Biomarkers of Systemic Inflammatory Response in Trauma Patients

(2014) Gershon Volpin et al.   INTERNATIONAL ORTHOPAEDICS

Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells

(2014) Xiaohong Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease

(2014) Michael B. Dinkins et al.   NEUROBIOLOGY OF AGING

Quantitative Proteomic Analysis of Gene Regulation by miR-34a and miR-34c

(2014) Olivia A. Ebner et al.   PLoS One

MicroRNA-147b Regulates Vascular Endothelial Barrier Function by Targeting ADAM15 Expression

(2014) Victor Chatterjee et al.   PLoS One

IL-6 in Inflammation, Immunity, and Disease

(2014) T. Tanaka et al.   Cold Spring Harbor Perspectives in Biology

Endothelial permeability and VE-cadherin

(2014) Julie Gavard   Cell Adhesion & Migration

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

A pig model for blunt chest trauma: no pulmonary edema in the early phase

(2013) David Couret et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Is Continuous Venovenous Hemofiltration Effective Against Severe Acute Pancreatitis?

(2013) Shiqi Wang et al.   ARTIFICIAL ORGANS

Proinflammatory role of epithelial cell–derived exosomes in allergic airway inflammation

(2013) Ankur Kulshreshtha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

(2013) Jianhua Li et al.   NATURE IMMUNOLOGY

Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis

(2013) Xiaoling Qiang et al.   NATURE MEDICINE

Exosome Secretion Is Enhanced by Invadopodia and Drives Invasive Behavior

(2013) Daisuke Hoshino et al.   Cell Reports

C-C motif chemokine CCL3 and canonical neutrophil attractants promote neutrophil extravasation through common and distinct mechanisms

(2012) C. A. Reichel et al.   BLOOD

Response time evaluation for emergency medical service as a part of its performance

(2012) François-Xavier Duchateau et al.   EMERGENCY MEDICINE JOURNAL

Rab11 regulates exocytosis of recycling vesicles at the plasma membrane

(2012) Senye Takahashi et al.   JOURNAL OF CELL SCIENCE

Protein Kinase D Regulates Cell Death Pathways in Experimental Pancreatitis

(2012) Jingzhen Yuan et al.   Frontiers in Physiology

Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflammed liver

(2011) Ahmad Amanzada et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Mechanism of Neutrophil Recruitment to the Lung After Pulmonary Contusion

(2011) J. Jason Hoth et al.   SHOCK

Pathogenesis of indirect (secondary) acute lung injury

(2011) Mario Perl et al.   Expert Review of Respiratory Medicine

Rolling Cell Adhesion

(2010) Rodger P. McEver et al.   Annual Review of Cell and Developmental Biology

The Mysterious Ways of the Chemokine CXCL5

(2010) Ekaterina K. Koltsova et al.   IMMUNITY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PECAM-1: Conflicts of interest in inflammation

(2010) Jamie R. Privratsky et al.   LIFE SCIENCES

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Pulmonary Contusion: An Update on Recent Advances in Clinical Management

(2010) Stephen M. Cohn et al.   WORLD JOURNAL OF SURGERY

Early Onset Pneumonia in Severe Chest Trauma: A Risk Factor Analysis

(2010) Pierre Michelet et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Inflammatory Alterations in a Novel Combination Model of Blunt Chest Trauma and Hemorrhagic Shock

(2010) Daniel H. Seitz et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Cell migration to the chemokine CXCL8: Paxillin is activated and regulates adhesion and cell motility

(2009) E. Cohen-Hillel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Clara Cell Protein (CC16), a Marker of Lung Epithelial Injury, Is Decreased in Plasma and Pulmonary Edema Fluid From Patients With Acute Lung Injury

(2009) Jonathan A. Kropski et al.   CHEST

The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies

(2009) J. Hol et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Pathophysiology of the systemic inflammatory response after major accidental trauma

(2009) Anne Brøchner et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY