Endothelial permeability and VE-cadherin

Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27

(2013) J. A. Young et al.   BLOOD

The C-terminus region of β-arrestin1 modulates VE-cadherin expression and endothelial cell permeability

(2013) Jagoda K Hebda et al.   Cell Communication and Signaling

Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1

(2013) Daniel E. Conway et al.   CURRENT BIOLOGY

Flow-dependent cellular mechanotransduction in atherosclerosis

(2013) D. E. Conway et al.   JOURNAL OF CELL SCIENCE

Wnt Activation of Immortalized Brain Endothelial Cells as a Tool for Generating a Standardized Model of the Blood Brain Barrier In Vitro

(2013) Roberta Paolinelli et al.   PLoS One

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

(2013) Makoto Hayashi et al.   Nature Communications

Tyrosine phosphorylation of DEP-1/CD148 as a mechanism controlling Src kinase activation, endothelial cell permeability, invasion, and capillary formation

(2012) K. Spring et al.   BLOOD

Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells

(2012) C. Giampietro et al.   BLOOD

PKCα Activation of p120-Catenin Serine 879 Phospho-Switch Disassembles VE-Cadherin Junctions and Disrupts Vascular Integrity

(2012) Emily Vandenbroucke St Amant et al.   CIRCULATION RESEARCH

SOX7 regulates the expression of VE-cadherin in the haemogenic endothelium at the onset of haematopoietic development

(2012) G. Costa et al.   DEVELOPMENT

The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2

(2012) Konstantin Gaengel et al.   DEVELOPMENTAL CELL

VEGF-Induced Vascular Permeability Is Mediated by FAK

(2012) Xiao Lei Chen et al.   DEVELOPMENTAL CELL

ETS-related Gene (ERG) Controls Endothelial Cell Permeability via Transcriptional Regulation of the Claudin 5 (CLDN5) Gene

(2012) Lei Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p120-catenin binding masks an endocytic signal conserved in classical cadherins

(2012) Benjamin A. Nanes et al.   JOURNAL OF CELL BIOLOGY

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

(2012) Stephan Huveneers et al.   JOURNAL OF CELL BIOLOGY

Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation

(2012) Armelle Le Guelte et al.   JOURNAL OF CELL SCIENCE

The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation

(2012) Ilse Timmerman et al.   MOLECULAR BIOLOGY OF THE CELL

VE-Cadherin Signaling Induces EB3 Phosphorylation to Suppress Microtubule Growth and Assemble Adherens Junctions

(2012) Yulia A. Komarova et al.   MOLECULAR CELL

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function

(2012) Kazuaki Yoshioka et al.   NATURE MEDICINE

microRNA-125b inhibits tube formation of blood vessels through translational suppression of VE-cadherin

(2012) F Muramatsu et al.   ONCOGENE

Vitronectin Increases Vascular Permeability by Promoting VE-Cadherin Internalization at Cell Junctions

(2012) Rong Li et al.   PLoS One

Glioblastoma Cell-Secreted Interleukin-8 Induces Brain Endothelial Cell Permeability via CXCR2

(2012) Julie Dwyer et al.   PLoS One

Reverse Genetics Screen in Zebrafish Identifies a Role of miR-142a-3p in Vascular Development and Integrity

(2012) Mukesh Kumar Lalwani et al.   PLoS One

Role of MicroRNAs 99b, 181a, and 181b in the Differentiation of Human Embryonic Stem Cells to Vascular Endothelial Cells

(2012) Nicole M. Kane et al.   STEM CELLS

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo

(2012) Fabrizio Orsenigo et al.   Nature Communications

RhoA-Mediated Signaling in Notch-Induced Senescence-Like Growth Arrest and Endothelial Barrier Dysfunction

(2011) Deepak Venkatesh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Jumping the barrier: VE-cadherin, VEGF and other angiogenic modifiers in cancer

(2011) Armelle Guelte et al.   BIOLOGY OF THE CELL

Caveolin-1 opens endothelial cell junctions by targeting catenins

(2011) Romy Kronstein et al.   CARDIOVASCULAR RESEARCH

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

(2011) Willem-Jan Pannekoek et al.   CELLULAR SIGNALLING

m-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-Cadherin Disorganization and Atherosclerosis

(2011) Takuro Miyazaki et al.   CIRCULATION

Angiogenic Sprouting Requires the Fine Tuning of Endothelial Cell Cohesion by the Raf-1/Rok-α Complex

(2011) Reiner Wimmer et al.   DEVELOPMENTAL CELL

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

(2011) Dörte Schulte et al.   EMBO JOURNAL

Epithelial Protein Lost In Neoplasm (EPLIN) Interacts with α-Catenin and Actin Filaments in Endothelial Cells and Stabilizes Vascular Capillary Networkin Vitro

(2011) Adeline Chervin-Pétinot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost

(2011) Anna A. Birukova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

p120 regulates endothelial permeability independently of its NH2 terminus and Rho binding

(2010) Crystal R. Herron et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Krüppel-Like Factor-4 Transcriptionally Regulates VE-Cadherin Expression and Endothelial Barrier Function

(2010) Colleen E. Cowan et al.   CIRCULATION RESEARCH

p120-Catenin Is Required for Mouse Vascular Development

(2010) Rebecca G. Oas et al.   CIRCULATION RESEARCH

VE-cadherin: at the front, center, and sides of endothelial cell organization and function

(2010) Elizabeth S Harris et al.   CURRENT OPINION IN CELL BIOLOGY

The Wnt/β-Catenin Pathway Modulates Vascular Remodeling and Specification by Upregulating Dll4/Notch Signaling

(2010) Monica Corada et al.   DEVELOPMENTAL CELL

Src-induced Tyrosine Phosphorylation of VE-cadherin Is Not Sufficient to Decrease Barrier Function of Endothelial Monolayers

(2010) Alejandro P. Adam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development

(2010) Xiaofeng Zhao et al.   JOURNAL OF CELL BIOLOGY

The PI3K p110α isoform regulates endothelial adherens junctions via Pyk2 and Rac1

(2010) Robert J. Cain et al.   JOURNAL OF CELL BIOLOGY

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

(2010) M. G. Lampugnani et al.   JOURNAL OF CELL SCIENCE

Remodeling of VE-cadherin junctions by the human herpes virus 8 G-protein coupled receptor

(2010) J Dwyer et al.   ONCOGENE

VE-Cadherin-Mediated Cell-Cell Interaction Suppresses Sprouting via Signaling to MLC2 Phosphorylation

(2009) Sabu Abraham et al.   CURRENT BIOLOGY

VE-PTP controls blood vessel development by balancing Tie-2 activity

(2009) Mark Winderlich et al.   JOURNAL OF CELL BIOLOGY

Endothelial barrier stabilization by a cyclic tandem peptide targeting VE-cadherin transinteraction in vitro and in vivo

(2009) W.-M. Heupel et al.   JOURNAL OF CELL SCIENCE

A Role for a CXCR2/Phosphatidylinositol 3-Kinase   Signaling Axis in Acute and Chronic Vascular Permeability

(2009) J. Gavard et al.   MOLECULAR AND CELLULAR BIOLOGY

p120-Catenin Inhibits VE-Cadherin Internalization through a Rho-independent Mechanism

(2009) Christine M. Chiasson et al.   MOLECULAR BIOLOGY OF THE CELL

Vascular Endothelial-Cadherin Stabilizes at Cell–Cell Junctions by Anchoring to Circumferential Actin Bundles through α- and β-Catenins in Cyclic AMP-Epac-Rap1 Signal-activated Endothelial Cells

(2009) Kazuomi Noda et al.   MOLECULAR BIOLOGY OF THE CELL

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin

(2008) G. M. Birdsey et al.   BLOOD

Role of Protein Tyrosine Phosphatase 1B in Vascular Endothelial Growth Factor Signaling and Cell–Cell Adhesions in Endothelial Cells

(2008) Yoshimasa Nakamura et al.   CIRCULATION RESEARCH

ADAM10 Regulates Endothelial Permeability and T-Cell Transmigration by Proteolysis of Vascular Endothelial Cadherin

(2008) Beate Schulz et al.   CIRCULATION RESEARCH

Angiopoietin-1 Prevents VEGF-Induced Endothelial Permeability by Sequestering Src through mDia

(2008) Julie Gavard et al.   DEVELOPMENTAL CELL

Serum Response Factor Is Required for Sprouting Angiogenesis and Vascular Integrity

(2008) Claudio Areias Franco et al.   DEVELOPMENTAL CELL

VE-cadherin is a critical endothelial regulator of TGF-β signalling

(2008) Noemi Rudini et al.   EMBO JOURNAL

Breaking the VE-cadherin bonds

(2008) Julie Gavard   FEBS LETTERS

Wnt/β-catenin signaling controls development of the blood–brain barrier

(2008) Stefan Liebner et al.   JOURNAL OF CELL BIOLOGY

TGF-β1 induces rearrangement of FLK-1-VE-cadherin-β-catenin complex at the adherens junction through VEGF-mediated signaling

(2008) Brandoch D. Cook et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The FGF system has a key role in regulating vascular integrity

(2008) Masahiro Murakami et al.   JOURNAL OF CLINICAL INVESTIGATION

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF

(2008) Astrid F. Nottebaum et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Remodeling of Endothelial Adherens Junctions by Kaposi's Sarcoma-Associated Herpesvirus

(2008) M. Mansouri et al.   JOURNAL OF VIROLOGY

VE-cadherin and claudin-5: it takes two to tango

(2008) Julie Gavard et al.   NATURE CELL BIOLOGY

Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1

(2008) Shigetomo Fukuhara et al.   NATURE CELL BIOLOGY

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

(2008) Pipsa Saharinen et al.   NATURE CELL BIOLOGY

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

(2008) Andrea Taddei et al.   NATURE CELL BIOLOGY

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

(2008) Christopher A Jones et al.   NATURE MEDICINE

Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration

(2007) P. Turowski et al.   JOURNAL OF CELL SCIENCE