Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks

Altered circular RNA expression profiles in the non-ischemic thalamus in focal cortical infarction mice

(2020) Fangming Li et al.   Aging-US

Non-coding RNA and neuroinflammation: implications for the therapy of stroke

(2019) Ling Shen et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2019) Valery L Feigin et al.   LANCET NEUROLOGY

Cellular and molecular mechanisms of sterile inflammation in ischaemic stroke

(2019) Koutarou Nakamura et al.   JOURNAL OF BIOCHEMISTRY

Apoptosis regulation in the penumbra after ischemic stroke: expression of pro- and antiapoptotic proteins

(2019) Anatoly B. Uzdensky   APOPTOSIS

Identification and functional analysis of circular RNAs induced in rats by middle cerebral artery occlusion

(2019) Xianchun Duan et al.   GENE

Neuroinflammation: friend and foe for ischemic stroke

(2019) Richard L. Jayaraj et al.   Journal of Neuroinflammation

Modifying PTEN recruitment promotes neuron survival, regeneration, and functional recovery after CNS injury

(2019) Alireza Pirsaraei Shabanzadeh et al.   Cell Death & Disease

miR-140-5p Attenuates Neuroinflammation and Brain Injury in Rats Following Intracerebral Hemorrhage by Targeting TLR4

(2019) Shunda Wang et al.   INFLAMMATION

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke

(2019) Kai-Di Ren et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Predictor of 90-day functional outcome after mechanical thrombectomy for large vessel occlusion stroke: NIHSS score of 10 or less at 24 hours

(2019) Mirja M. Wirtz et al.   JOURNAL OF NEUROSURGERY

Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke

(2018) Bing Han et al.   Autophagy

MicRNA-320 facilitates the brain parenchyma injury via regulating IGF-1 during cerebral I/R injury in mice

(2018) Lizhen Liang et al.   BIOMEDICINE & PHARMACOTHERAPY

Knockdown of lncRNA MALAT1 attenuates acute myocardial infarction through miR-320-Pten axis

(2018) Hao Hu et al.   BIOMEDICINE & PHARMACOTHERAPY

circRNAs in Cancer

(2018) Ines Lucia Patop et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

LncRNA SNHG1 regulates cerebrovascular pathologies as a competing endogenous RNA through HIF-1α/VEGF signaling in ischemic stroke

(2018) Lin Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Epstein−Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas

(2018) Eleni Anastasiadou et al.   LEUKEMIA

Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4

(2018) Yasir Abdul et al.   MOLECULAR NEUROBIOLOGY

Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis

(2018) Alexandre Vallée et al.   Frontiers in Immunology

Prediction of Outcome in Patients With Acute Ischemic Stroke Based on Initial Severity and Improvement in the First 24 h

(2018) Anke Wouters et al.   Frontiers in Neurology

The Biogenesis, Functions, and Challenges of Circular RNAs

(2018) Xiang Li et al.   MOLECULAR CELL

Oxidative stress-modulating drugs have preferential anticancer effects - involving the regulation of apoptosis, DNA damage, endoplasmic reticulum stress, autophagy, metabolism, and migration

(2018) Jen-Yang Tang et al.   SEMINARS IN CANCER BIOLOGY

Post-stroke inflammation—target or tool for therapy?

(2018) Kate Lykke Lambertsen et al.   ACTA NEUROPATHOLOGICA

A map of human circular RNAs in clinically relevant tissues

(2017) Philipp G. Maass et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

CircRNA: functions and properties of a novel potential biomarker for cancer

(2017) Shujuan Meng et al.   Molecular Cancer

Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection

(2017) Xiang Li et al.   MOLECULAR CELL

Circular RNA Expression Profiles Alter Significantly in Mouse Brain After Transient Focal Ischemia

(2017) Suresh L. Mehta et al.   STROKE

miR-145-5p/Nurr1/TNF-α Signaling-Induced Microglia Activation Regulates Neuron Injury of Acute Cerebral Ischemic/Reperfusion in Rats

(2017) Xuemei Xie et al.   Frontiers in Molecular Neuroscience

Circular RNAs: Identification, biogenesis and function

(2016) Karoline K. Ebbesen et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Oxidized LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-oxidase activation

(2016) Deepika Awasthi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Network biology concepts in complex disease comorbidities

(2016) Jessica Xin Hu et al.   NATURE REVIEWS GENETICS

Thromboinflammation in Stroke Brain Damage

(2016) Simon F. De Meyer et al.   STROKE

Targeting Oxidative Stress in Central Nervous System Disorders

(2016) Manisha Patel   TRENDS IN PHARMACOLOGICAL SCIENCES

Estrogen-IGF-1 interactions in neuroprotection: Ischemic stroke as a case study

(2015) Farida Sohrabji   FRONTIERS IN NEUROENDOCRINOLOGY

MiR-129-2 functions as a tumor suppressor in glioma cells by targeting HMGB1 and is down-regulated by DNA methylation

(2015) Yu Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy

(2015) Renu A. Kowluru et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Regulation of circRNA biogenesis

(2015) Ling-Ling Chen et al.   RNA Biology

Animal models of ischemic stroke and their application in clinical research

(2015) Christoph Kleinschnitz et al.   Drug Design Development and Therapy

Hypoxia-inducible miR-182 enhances HIF1α signaling via targeting PHD2 and FIH1 in prostate cancer

(2015) Yan Li et al.   Scientific Reports

CIRI: an efficient and unbiased algorithm for de novo circular RNA identification

(2015) Yuan Gao et al.   GENOME BIOLOGY

Inflammation and Neuroprotection in Traumatic Brain Injury

(2015) Kara N. Corps et al.   JAMA Neurology

mir-129-5p Attenuates Irradiation-Induced Autophagy and Decreases Radioresistance of Breast Cancer Cells by Targeting HMGB1

(2015) Jing Luo et al.   MEDICAL SCIENCE MONITOR

Biogenesis of Circular RNAs

(2014) Quentin Vicens et al.   CELL

Rac-1 as a New Therapeutic Target in Cerebro- and Cardio-Vascular Diseases

(2014) Albino Carrizzo et al.   CURRENT DRUG TARGETS

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

circBase: a database for circular RNAs

(2014) Petar Glažar et al.   RNA

Essential Role of Program Death 1-Ligand 1 in Regulatory T-Cell–Afforded Protection Against Blood–Brain Barrier Damage After Stroke

(2014) Peiying Li et al.   STROKE

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2

(2013) Rui Zhang et al.   TUMOR BIOLOGY

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Circular RNA (circRNA) in Alzheimer's disease (AD)

(2013) Walter J. Lukiw   Frontiers in Genetics

Pathophysiologic Cascades in Ischemic Stroke

(2012) Changhong Xing et al.   International Journal of Stroke

Microvascular protection is essential for successful neuroprotection in stroke

(2012) Yasemin Gursoy-Ozdemir et al.   JOURNAL OF NEUROCHEMISTRY

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer

(2011) H Zhang et al.   CELL DEATH AND DIFFERENTIATION

Stroke genetics

(2011) H. S. Markus   HUMAN MOLECULAR GENETICS

miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes

(2011) Yi-Bing Ouyang et al.   MITOCHONDRION

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Missing heritability and strategies for finding the underlying causes of complex disease

(2010) Evan E. Eichler et al.   NATURE REVIEWS GENETICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

The complexity of neurobiological processes in acute ischemic stroke

(2009) R. Brouns et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE