Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association

(2017) Philip B. Gorelick et al.   STROKE

Effects of the TLR4 signaling pathway on apoptosis of neuronal cells in diabetes mellitus complicated with cerebral infarction in a rat model

(2017) Chao Li et al.   Scientific Reports

TAK-242, an Antagonist for Toll-like Receptor 4, Protects against Acute Cerebral Ischemia/Reperfusion Injury in Mice

(2015) Fang Hua et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Stroke Prevalence, Mortality and Disability-Adjusted Life Years in Adults Aged 20-64 Years in 1990-2013: Data from the Global Burden of Disease 2013 Study

(2015) Rita V. Krishnamurthi et al.   NEUROEPIDEMIOLOGY

Metformin Treatment in the Period After Stroke Prevents Nitrative Stress and Restores Angiogenic Signaling in the Brain in Diabetes

(2014) Mohammed Abdelsaid et al.   DIABETES

Targets of vascular protection in acute ischemic stroke differ in type 2 diabetes

(2013) Aisha I. Kelly-Cobbs et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Thioredoxin-Interacting Protein Expression Is Required for VEGF-Mediated Angiogenic Signal in Endothelial Cells

(2013) Mohammed A. Abdelsaid et al.   ANTIOXIDANTS & REDOX SIGNALING

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

(2013) J. D. Belcher et al.   BLOOD

Cerebral Neovascularization and Remodeling Patterns in Two Different Models of Type 2 Diabetes

(2013) Roshini Prakash et al.   PLoS One

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase

(2013) Amira Othman et al.   PLoS One

Vascularization Pattern After Ischemic Stroke is Different in Control Versus Diabetic Rats

(2013) Roshini Prakash et al.   STROKE

Toll-Like Receptor Signaling

(2013) K.-H. Lim et al.   Cold Spring Harbor Perspectives in Biology

Toll-Like Receptor 4 Activation in Microvascular Endothelial Cells Triggers a Robust Inflammatory Response and Cross Talk With Mononuclear Cells via Interleukin-6

(2012) Zhongyang Lu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Enhanced Cerebral but Not Peripheral Angiogenesis in the Goto-Kakizaki Model of Type 2 Diabetes Involves VEGF and Peroxynitrite Signaling

(2012) R. Prakash et al.   DIABETES

Increased expression of Toll-like receptors 2 and 4 is associated with poor outcome in intracerebral hemorrhage

(2012) Manuel Rodríguez-Yáñez et al.   JOURNAL OF NEUROIMMUNOLOGY

Functional recovery after ischemic stroke--A matter of age: Data from the Austrian Stroke Unit Registry

(2012) M. Knoflach et al.   NEUROLOGY

Tissue plasminogen activator treatment of stroke in type-1 diabetes rats

(2012) R. Ning et al.   NEUROSCIENCE

Thrombin and hemin as central factors in the mechanisms of intracerebral hemorrhage–induced secondary brain injury and as potential targets for intervention

(2012) Ranjith Babu et al.   Neurosurgical Focus

Angiogenesis

(2012) Adviye Ergul et al.   STROKE

Cerebrovascular Complications of Diabetes: Focus on Stroke

(2012) Adviye Ergul et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Differential Effect of Nimodipine in Attenuating Iron-Induced Toxicity in Brain- and Blood–Brain Barrier-Associated Cell Types

(2011) J. A. Lockman et al.   NEUROCHEMICAL RESEARCH

Molecular Pathophysiology of Cerebral Hemorrhage

(2011) Jaroslaw Aronowski et al.   STROKE

Vascular Protection in Diabetic Stroke: Role of Matrix Metalloprotease-Dependent Vascular Remodeling

(2010) Mostafa M Elgebaly et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia

(2010) K. Hyakkoku et al.   NEUROSCIENCE

Mechanisms and targets for angiogenic therapy after stroke

(2010) Deepti Navaratna et al.   Cell Adhesion & Migration

Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke

(2009) Stephen R. Robinson et al.   REDOX REPORT