VgrG-dependent effectors and chaperones modulate the assembly of the type VI secretion system

A novel stabilization mechanism for the type VI secretion system sheath

(2021) Patricia Bernal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of a lysozyme-like effector TseP and secretion co-dependence of the type VI secretion system in Aeromonas dhakensis SSU

(2021) Xiaoye Liang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Manipulating the type VI secretion system spike to shuttle passenger proteins

(2020) Sarah Wettstadt et al.   PLoS One

Envelope stress responses defend against type six secretion system attacks independently of immunity proteins

(2020) Steven J. Hersch et al.   Nature Microbiology

Structural basis for loading and inhibition of a bacterial T6 SS phospholipase effector by the VgrG spike

(2020) Nicolas Flaugnatti et al.   EMBO JOURNAL

Intramolecular chaperone-mediated secretion of an Rhs effector toxin by a type VI secretion system

(2020) Tong-Tong Pei et al.   Nature Communications

Differential Cellular Response to Translocated Toxic Effectors and Physical Penetration by the Type VI Secretion System

(2020) Fatima Kamal et al.   Cell Reports

TssA–TssM–TagA interaction modulates type VI secretion system sheath-tube assembly in Vibrio cholerae

(2020) Maria Silvina Stietz et al.   Nature Communications

The β-encapsulation cage of rearrangement hotspot (Rhs) effectors is required for type VI secretion

(2020) Sonya L. Donato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly and Subcellular Localization of Bacterial Type VI Secretion Systems

(2019) Jing Wang et al.   Annual Review of Microbiology

Delivery of the Pseudomonas aeruginosa Phospholipase Effectors PldA and PldB in a VgrG- and H2-T6SS-Dependent Manner

(2019) Sarah Wettstadt et al.   Frontiers in Microbiology

Diverse roles of TssA‐like proteins in the assembly of bacterial type VI secretion systems

(2019) Johannes Paul Schneider et al.   EMBO JOURNAL

An onboard checking mechanism ensures effector delivery of the type VI secretion system in Vibrio cholerae

(2019) Xiaoye Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein-Injection Machines in Bacteria

(2018) Jorge E. Galán et al.   CELL

Exopolysaccharide protectsVibrio choleraefrom exogenous attacks by the type 6 secretion system

(2018) Jonida Toska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The type VI secretion system deploys antifungal effectors against microbial competitors

(2018) Katharina Trunk et al.   Nature Microbiology

A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone–co-chaperone complex

(2018) Brianne J. Burkinshaw et al.   Nature Microbiology

Mechanism of loading and translocation of type VI secretion system effector Tse6

(2018) Dennis Quentin et al.   Nature Microbiology

In vivo TssA proximity labelling during type VI secretion biogenesis reveals TagA as a protein that stops and holds the sheath

(2018) Yoann G. Santin et al.   Nature Microbiology

Vibrio choleraetype 6 secretion system effector trafficking in target bacterial cells

(2017) Brian T. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hcp proteins fused with diverse extended-toxin domains represent a novel pattern of antibacterial effectors in type VI secretion systems

(2017) Jiale Ma et al.   Virulence

Microbial Herd Protection Mediated by Antagonistic Interaction in Polymicrobial Communities

(2016) Megan J. Q. Wong et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery

(2016) Nicolas Flaugnatti et al.   MOLECULAR MICROBIOLOGY

Priming and polymerization of a bacterial contractile tail structure

(2016) Abdelrahim Zoued et al.   NATURE

VgrG C terminus confers the type VI effector transport specificity and is required for binding with PAAR and adaptor–effector complex

(2016) Devanand D. Bondage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chimeric adaptor proteins translocate diverse type VI secretion system effectors in Vibrio cholerae

(2015) D. Unterweger et al.   EMBO JOURNAL

Biogenesis and structure of a type VI secretion membrane core complex

(2015) Eric Durand et al.   NATURE

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Identification of divergent type VI secretion effectors using a conserved chaperone domain

(2015) Xiaoye Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Established Microbial Colonies Can Survive Type VI Secretion Assault

(2015) David Bruce Borenstein et al.   PLoS Computational Biology

The VgrG Proteins Are “à la Carte” Delivery Systems for Bacterial Type VI Effectors

(2014) Abderrahman Hachani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetically distinct pathways guide effector export through the type VI secretion system

(2014) John C. Whitney et al.   MOLECULAR MICROBIOLOGY

Type VI secretion system effectors: poisons with a purpose

(2014) Alistair B. Russell et al.   NATURE REVIEWS MICROBIOLOGY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

A View to a Kill: The Bacterial Type VI Secretion System

(2013) Brian T. Ho et al.   Cell Host & Microbe

Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates

(2013) Julie M. Silverman et al.   MOLECULAR CELL

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors

(2013) Alistair B. Russell et al.   NATURE

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

(2013) Mikhail M. Shneider et al.   NATURE

Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae

(2013) T. G. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rhs proteins from diverse bacteria mediate intercellular competition

(2013) S. Koskiniemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New secreted toxins and immunity proteins encoded within the Type VI secretion system gene cluster ofSerratia marcescens

(2012) Grant English et al.   MOLECULAR MICROBIOLOGY

Type VI secretion requires a dynamic contractile phage tail-like structure

(2012) M. Basler et al.   NATURE

Type VI Secretion System inPseudomonas aeruginosa

(2011) Abderrahman Hachani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Type VI secretion delivers bacteriolytic effectors to target cells

(2011) Alistair B. Russell et al.   NATURE

Genetic Analysis of Anti-Amoebae and Anti-Bacterial Activities of the Type VI Secretion System in Vibrio cholerae

(2011) Jun Zheng et al.   PLoS One

A Type VI Secretion System of Pseudomonas aeruginosa Targets a Toxin to Bacteria

(2010) Rachel D. Hood et al.   Cell Host & Microbe

Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources?

(2009) Frédéric Boyer et al.   BMC GENOMICS

Translocation of a Vibrio cholerae Type VI Secretion Effector Requires Bacterial Endocytosis by Host Cells

(2009) Amy T. Ma et al.   Cell Host & Microbe

The type VI secretion system: translocation of effectors and effector-domains

(2009) Stefan Pukatzki et al.   CURRENT OPINION IN MICROBIOLOGY

Molecular characterization of a functional type VI secretion system from a clinical isolate of Aeromonas hydrophila

(2007) Giovanni Suarez et al.   MICROBIAL PATHOGENESIS