Cobalt-Catalyzed C(sp2)–C(sp3) Suzuki–Miyaura Cross-Coupling Enabled by Well-Defined Precatalysts with L,X-Type Ligands

Cobalt-Catalyzed Coupling of Aryl Chlorides with Aryl Boron Esters Activated by Alkoxides

(2021) Sanita B. Tailor et al.   ACS Catalysis

Nickel‐Catalyzed Regioselective Alkenylarylation of γ,δ‐Alkenyl Ketones via Carbonyl Coordination

(2021) Roshan K. Dhungana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Process Chemistry Benchmark for sp2–sp3 Cross Couplings

(2021) Gregory L. Beutner et al.   JOURNAL OF ORGANIC CHEMISTRY

Advancing Base-Metal Catalysis: Development of a Screening Method for Nickel-Catalyzed Suzuki–Miyaura Reactions of Pharmaceutically Relevant Heterocycles

(2021) Matthew J. Goldfogel et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design

(2021) Murugaiah A. M. Subbaiah et al.   JOURNAL OF MEDICINAL CHEMISTRY

Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp2)–C(sp3) Cross-Coupling Methods by Library Synthesis

(2020) Amanda W. Dombrowski et al.   ACS Medicinal Chemistry Letters

Cobalt-Catalyzed Cross-Couplings between Alkyl Halides and Grignard Reagents

(2020) Amandine Guérinot et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Synergy and Struggle of EPR, Magnetometry and NMR: A Case Study of Magnetic Interaction Parameters in a Six-Coordinate Cobalt(II) Complex

(2020) Alexander A. Pavlov et al.   INORGANIC CHEMISTRY

Impact of Cross-Coupling Reactions in Drug Discovery and Development

(2020) Melissa J. Buskes et al.   MOLECULES

Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9)

(2020) Christopher P. Mussari et al.   ACS Medicinal Chemistry Letters

Cobalt-Catalyzed C(sp2)–C(sp3) Suzuki–Miyaura Cross Coupling

(2020) Jacob R. Ludwig et al.   ORGANIC LETTERS

Spirocyclic Scaffolds in Medicinal Chemistry

(2020) Kerstin Hiesinger et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phenoxyimine Ligands Bearing Nitrogen-Containing Second Coordination Spheres for Zinc Catalyzed Stereoselective Ring-Opening Polymerization of rac-Lactide

(2019) Min Li et al.   ORGANOMETALLICS

Organocobalt Complexes as Sources of Carbon-Centered Radicals for Organic and Polymer Chemistries

(2019) Jérémy Demarteau et al.   CHEMICAL REVIEWS

Unexpected Precatalyst σ-Ligand Effects in Phenoxyimine Zr-Catalyzed Ethylene/1-Octene Copolymerizations

(2019) Yanshan Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Evolution of High-Throughput Experimentation in Pharmaceutical Development, and Perspectives on the Future

(2019) Steven M Mennen et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Revisiting Claims of the Iron-, Cobalt-, Nickel-, and Copper-Catalyzed Suzuki Biaryl Cross-Coupling of Aryl Halides with Aryl Boronic Acids

(2019) Sanita B. Tailor et al.   ORGANOMETALLICS

Cobalt-Catalyzed Cross-Coupling Reactions of Aryl Triflates and Lithium Arylborates

(2019) Hung A. Duong et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Studies into the Oxidative Addition of Co(I) Complexes: Combining Electroanalytical Techniques with Parameterization

(2019) Christopher Sandford et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural elucidation of N^O (ethylimino-methyl)phenol Fe(II) and Co(II) complexes and their applications in ethylene oligomerization catalysis

(2019) Makhosonke Ngcobo et al.   Molecular Catalysis

Cobalt Schiff base complexes: Synthesis characterization and catalytic application in Suzuki–Miyaura reaction

(2018) Rasheeda M. Ansari et al.   CHINESE JOURNAL OF CHEMICAL ENGINEERING

Air-Stable Cobalt(II) and Nickel(II) Complexes with Schiff Base Ligand for Catalyzing Suzuki–Miyaura Cross-Coupling Reaction

(2018) R. M. Ansari et al.   RUSSIAN JOURNAL OF COORDINATION CHEMISTRY

Mechanistic Interrogation of Co/Ni-Dual Catalyzed Hydroarylation

(2018) Sophia L. Shevick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal Structure and Corrosion Inhibition Properties of Ferrocenyl- and Phenylendiamine-Iminomethylphenoxy Cobalt Complexes

(2017) Nadra Belhadj et al.   JOURNAL OF CHEMICAL CRYSTALLOGRAPHY

Parameterization of phosphine ligands demonstrates enhancement of nickel catalysis via remote steric effects

(2017) Kevin Wu et al.   Nature Chemistry

Cobalt-Catalyzed Cross-Coupling Reactions of Arylboronic Esters and Aryl Halides

(2017) Hung A. Duong et al.   ORGANOMETALLICS

Toxicity of Metal Compounds: Knowledge and Myths

(2017) Ksenia S. Egorova et al.   ORGANOMETALLICS

Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes

(2017) Gregory C. Fu   ACS Central Science

Well-defined nickel and palladium precatalysts for cross-coupling

(2017) Nilay Hazari et al.   Nature Reviews Chemistry

Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids

(2016) Jie Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxetanes: Recent Advances in Synthesis, Reactivity, and Medicinal Chemistry

(2016) James A. Bull et al.   CHEMICAL REVIEWS

Stereoelectronic Chameleons: The Donor-Acceptor Dichotomy of Functional Groups

(2016) Sergey Z. Vatsadze et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cobalt(II)-Based Single-Ion Magnets with Distorted Pseudotetrahedral [N2O2] Coordination: Experimental and Theoretical Investigations

(2016) Sven Ziegenbalg et al.   INORGANIC CHEMISTRY

Challenging nickel-catalysed amine arylations enabled by tailored ancillary ligand design

(2016) Christopher M. Lavoie et al.   Nature Communications

Active Species and Mechanistic Pathways in Iron-Catalyzed C–C Bond-Forming Cross-Coupling Reactions

(2016) Carlo Cassani et al.   ACS Catalysis

Insight into Transmetalation Enables Cobalt-Catalyzed Suzuki–Miyaura Cross Coupling

(2016) Jamie M. Neely et al.   ACS Central Science

How Low Does Iron Go? Chasing the Active Species in Fe-Catalyzed Cross-Coupling Reactions

(2015) Robin B. Bedford   ACCOUNTS OF CHEMICAL RESEARCH

Characterization, crystal structures, electrochemical and antibacterial studies of four new binuclear cobalt(III) complexes derived from o-aminobenzyl alcohol

(2015) Mehdi Salehi et al.   INORGANICA CHIMICA ACTA

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

(2015) Dean G. Brown et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iron(II) Active Species in Iron–Bisphosphine Catalyzed Kumada and Suzuki–Miyaura Cross-Couplings of Phenyl Nucleophiles and Secondary Alkyl Halides

(2015) Stephanie L. Daifuku et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-catalysed cross-coupling: an untapped potential

(2015) Surendra Thapa et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cobalt co-catalysis for cross-electrophile coupling: diarylmethanes from benzyl mesylates and aryl halides

(2015) Laura K. G. Ackerman et al.   Chemical Science

Expedient Iron-Catalyzed Coupling of Alkyl, Benzyl and Allyl Halides with Arylboronic Esters

(2014) Robin B. Bedford et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

Formation and Structure of a Cobalt(III) Complex Containing a Nonstabilized Pyridinium Ylide Ligand

(2014) Patrizia Siega et al.   ORGANOMETALLICS

Nickel-Catalyzed Carbon–Carbon Bond-Forming Reactions of Unactivated Tertiary Alkyl Halides: Suzuki Arylations

(2013) Susan L. Zultanski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism and Selectivity in Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Halides with Alkyl Halides

(2013) Soumik Biswas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Alkyl-Alkyl Suzuki-Miyaura Coupling

(2012) Takuji Hatakeyama et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bis(8-quinolinolato)aluminum ethyl complexes: Iso-Selective Initiators for rac-Lactide Polymerization

(2012) Clare Bakewell et al.   ORGANOMETALLICS

Escape from Flatland 2: complexity and promiscuity

(2012) Frank Lovering   MedChemComm

Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals

(2011) Javier Magano et al.   CHEMICAL REVIEWS

Pd-catalyzed cross-coupling reactions of alkyl halides

(2011) Nobuaki Kambe et al.   CHEMICAL SOCIETY REVIEWS

Stereospecific Cross-Coupling between Alkenylboronates and Alkyl Halides Catalyzed by Iron–Bisphosphine Complexes

(2011) Toru Hashimoto et al.   JOURNAL OF ORGANIC CHEMISTRY

Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective

(2011) Xile Hu   Chemical Science

Cobalt-Catalyzed Cross-Coupling Reactions

(2010) Gérard Cahiez et al.   CHEMICAL REVIEWS

Asymmetric Suzuki Cross-Couplings of Activated Secondary Alkyl Electrophiles: Arylations of Racemic α-Chloroamides

(2010) Pamela M. Lundin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Suzuki−Miyaura Coupling of Alkyl Halides

(2010) Takuji Hatakeyama et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

(2010) P. A. Clemons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

(2008) Ruben Martin et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Development of Versatile Methods for Palladium-Catalyzed Coupling Reactions of Aryl Electrophiles through the Use of P(t-Bu)3and PCy3as Ligands

(2008) Gregory C. Fu   ACCOUNTS OF CHEMICAL RESEARCH

Well-Defined N-Heterocyclic Carbenes−Palladium(II) Precatalysts for Cross-Coupling Reactions

(2008) Nicolas Marion et al.   ACCOUNTS OF CHEMICAL RESEARCH

Corroborative cobalt and zinc model compounds of α-amino-β-carboxymuconic-ε-semialdehyde decarboxylase (ACMSD)

(2008) Jessica Gätjens et al.   DALTON TRANSACTIONS

Molecular design of mononuclear complexes of acyclic Schiff-base ligands

(2008) A. D. Garnovskii et al.   JOURNAL OF COORDINATION CHEMISTRY

Enantioselective Alkyl−Alkyl Suzuki Cross-Couplings of Unactivated Homobenzylic Halides

(2008) Bunnai Saito et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY