An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes

Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes

(2021) Joana Faria et al.   Nature Microbiology

TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei

(2021) Carys Davies et al.   NUCLEIC ACIDS RESEARCH

Trypanosome KKIP1 Dynamically Links the Inner Kinetochore to a Kinetoplastid Outer Kinetochore Complex

(2021) Lorenzo Brusini et al.   Frontiers in Cellular and Infection Microbiology

Higher-order organization of biomolecular condensates

(2021) Charlotte M. Fare et al.   Open Biology

The nucleolus as a multiphase liquid condensate

(2020) Denis L. J. Lafontaine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic colocalization of 2 simultaneously active VSG expression sites within a single expression-site body in Trypanosoma brucei

(2019) James Budzak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated Control of rRNA Processing by RNA Polymerase I

(2019) Catherine E. Scull et al.   TRENDS IN GENETICS

Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

(2019) Joana Faria et al.   Nature Communications

Identification of four unconventional kinetoplastid kinetochore proteins KKT22–25 in Trypanosoma brucei

(2019) Olga O. Nerusheva et al.   Open Biology

Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes

(2018) Igor Cestari et al.   CURRENT GENOMICS

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome organization and DNA accessibility control antigenic variation in trypanosomes

(2018) Laura S. M. Müller et al.   NATURE

Human African trypanosomiasis

(2017) Philippe Büscher et al.   LANCET

The role of genomic location and flanking 3′UTR in the generation of functional levels of variant surface glycoprotein in Trypanosoma brucei

(2017) Sophie Ridewood et al.   MOLECULAR MICROBIOLOGY

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

TrypTag.org: A Trypanosome Genome-wide Protein Localisation Resource

(2017) Samuel Dean et al.   TRENDS IN PARASITOLOGY

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

(2017) Louise E. Kerry et al.   PLoS Neglected Tropical Diseases

Cajal body function in genome organization and transcriptome diversity

(2016) Iain A. Sawyer et al.   BIOESSAYS

High-resolution analysis of multi-copy variant surface glycoprotein gene expression sites in African trypanosomes

(2016) Sebastian Hutchinson et al.   BMC GENOMICS

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Gene expression in Kinetoplastids

(2016) CE Clayton   CURRENT OPINION IN MICROBIOLOGY

Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing

(2016) Tassa Saldi et al.   JOURNAL OF MOLECULAR BIOLOGY

VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

(2016) Lucy Glover et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA modification in Cajal bodies

(2016) U. Thomas Meier   RNA Biology

Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein

(2016) Nitika Badjatia et al.   PLoS Pathogens

NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins

(2015) Jonathan Bizarro et al.   NUCLEIC ACIDS RESEARCH

SIMcheck: a Toolbox for Successful Super-resolution Structured Illumination Microscopy

(2015) Graeme Ball et al.   Scientific Reports

A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids

(2015) S. Dean et al.   Open Biology

How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?

(2015) Angela Schwede et al.   PLoS Pathogens

Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

(2014) Jonathan Bizarro et al.   JOURNAL OF CELL BIOLOGY

Antigenic variation in African trypanosomes

(2014) David Horn   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

(2014) Abeer Fadda et al.   MOLECULAR MICROBIOLOGY

SUMOylation by the E3 Ligase TbSIZ1/PIAS1 Positively Regulates VSG Expression in Trypanosoma brucei

(2014) Diana López-Farfán et al.   PLoS Pathogens

Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly

(2013) Benjamin Rothé et al.   NUCLEIC ACIDS RESEARCH

A modular and optimized single marker system for generating Trypanosoma brucei cell lines expressing T7 RNA polymerase and the tetracycline repressor

(2012) S. K. Poon et al.   Open Biology

Cajal bodies: where form meets function

(2012) Martin Machyna et al.   Wiley Interdisciplinary Reviews-RNA

snRNA-specific role of SMN in trypanosome snRNP biogenesis in vivo

(2011) Nicolas Jaé et al.   RNA Biology

The Pre-mRNA Splicing Machinery of Trypanosomes: Complex or Simplified?

(2010) Arthur Günzl   EUKARYOTIC CELL

Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters

(2010) Gabriela Schumann Burkard et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

AtNUFIP, an essential protein for plant development, reveals the impact of snoRNA gene organisation on the assembly of snoRNPs and rRNA methylation in Arabidopsis thaliana

(2010) Julie Rodor et al.   PLANT JOURNAL

Red fluorescent Xenopus laevis: a new tool for grafting analysis

(2009) Christoph Waldner et al.   BMC DEVELOPMENTAL BIOLOGY

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

(2008) Séverine Boulon et al.   JOURNAL OF CELL BIOLOGY

Telomeric Expression Sites Are Highly Conserved in Trypanosoma brucei

(2008) Christiane Hertz-Fowler et al.   PLoS One