TNF-α-induced protein 8-like 2 negatively regulates the immune function of dendritic cells by suppressing autophagy via the TAK1/JNK pathway in septic mice

Sestrin2 protects dendritic cells against endoplasmic reticulum stress-related apoptosis induced by high mobility group box-1 protein

(2020) Li-Xue Wang et al.   Cell Death & Disease

Combination of Rapamycin and MK-2206 Induced Cell Death via Autophagy and Necroptosis in MYCN-Amplified Neuroblastoma Cell Lines

(2020) Yudi Dong et al.   Frontiers in Pharmacology

Regulation of Beclin 1-Mediated Autophagy by Oncogenic Tyrosine Kinases

(2020) Silvia Vega-Rubín-de-Celis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective effects of rapamycin induced autophagy on CLP septic mice

(2019) Zhenxia Wang et al.   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

PDIA6 modulates apoptosis and autophagy of non-small cell lung cancer cells via the MAP4K1/JNK signaling pathway

(2019) Yuxin Bai et al.   EBioMedicine

Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation

(2019) Nina Germic et al.   CELL DEATH AND DIFFERENTIATION

Regulation of dendritic cell function improves survival in experimental sepsis through immune chaperone

(2019) Pengfei Li et al.   Innate Immunity

TIPE2 suppresses Pseudomonas aeruginosa keratitis by inhibiting NF-κB signaling and the infiltration of inflammatory cells

(2019) Qun Wang et al.   JOURNAL OF INFECTIOUS DISEASES

Impaired Autophagy in CD11b + Dendritic Cells Expands CD4 + Regulatory T Cells and Limits Atherosclerosis in Mice

(2019) Marc Clement et al.   CIRCULATION RESEARCH

Tumor Necrosis Factor-α-Induced Protein 8-like 2 Downregulation Reduces CD4⁺ T Lymphocyte Apoptosis in Mice with Thermal Injury

(2019) He Huang et al.   MEDICAL SCIENCE MONITOR

Autophagy in dendritic cells

(2018) Ghita Ghislat et al.   Cellular & Molecular Immunology

Sepsis and septic shock

(2018) Maurizio Cecconi et al.   LANCET

Dendritic cells in sepsis: Potential immunoregulatory cells with therapeutic potential

(2018) V. Kumar   MOLECULAR IMMUNOLOGY

Gintonin stimulates autophagic flux in primary cortical astrocytes

(2018) Md. Ataur Rahman et al.   Journal of Ginseng Research

Contribution of Dendritic Cell Responses to Sepsis-Induced Immunosuppression and to Susceptibility to Secondary Pneumonia

(2018) Marwan Bouras et al.   Frontiers in Immunology

Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014

(2017) Chanu Rhee et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mass spectrometry for the discovery of biomarkers of sepsis

(2017) Katelyn R. Ludwig et al.   Molecular BioSystems

Advances in the understanding and treatment of sepsis-induced immunosuppression

(2017) Fabienne Venet et al.   Nature Reviews Nephrology

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

The immune system's role in sepsis progression, resolution, and long-term outcome

(2016) Matthew J. Delano et al.   IMMUNOLOGICAL REVIEWS

TIPE2 (Tumor Necrosis Factor α-induced Protein 8-like 2) Is a Novel Negative Regulator of TAK1 Signal

(2016) Michitaka Oho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of tumor necrosis factor-α induced protein 8 like-2 on immune function of dendritic cells in mice following acute insults

(2016) Ying-yi Luan et al.   Oncotarget

Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion

(2015) Caroline Mauvezin et al.   Autophagy

Dendritic Cells Modulate Lung Response to Pseudomonas aeruginosa in a Murine Model of Sepsis-Induced Immune Dysfunction

(2014) F. Pene et al.   JOURNAL OF IMMUNOLOGY

Benchmarking the Incidence and Mortality of Severe Sepsis in the United States*

(2013) David F. Gaieski et al.   CRITICAL CARE MEDICINE

TAK1-JNK Axis Mediates Survival Signal through Mcl1 Stabilization in Activated T Cells

(2013) Y. Hirata et al.   JOURNAL OF IMMUNOLOGY

The Significance and Regulatory Mechanisms of Innate Immune Cells in the Development of Sepsis

(2013) Ying-Yi Luan et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View

(2013) Wibke Schulte et al.   MEDIATORS OF INFLAMMATION

Host innate immune responses to sepsis

(2013) Willem Joost Wiersinga et al.   Virulence

A comparison of critical care research funding and the financial burden of critical illness in the United States*

(2012) Craig M. Coopersmith et al.   CRITICAL CARE MEDICINE

TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection

(2012) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Modulation of Dendritic Cell Differentiation in the Bone Marrow Mediates Sustained Immunosuppression after Polymicrobial Sepsis

(2010) E. Pastille et al.   JOURNAL OF IMMUNOLOGY

International Study of the Prevalence and Outcomes of Infection in Intensive Care Units

(2009) Jean-Louis Vincent   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MODULATION OF THE BCL-2 FAMILY BLOCKS SEPSIS-INDUCED DEPLETION OF DENDRITIC CELLS AND MACROPHAGES

(2009) Octavia M. Peck-Palmer et al.   SHOCK

Development and validation of a model for prediction of mortality in patients with acute burn injury

(2008)   BRITISH JOURNAL OF SURGERY

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis

(2008) Honghong Sun et al.   CELL

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL