TIPE2 (Tumor Necrosis Factor α-induced Protein 8-like 2) Is a Novel Negative Regulator of TAK1 Signal

Tnfaip8 l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model

(2014) Ji-Young Ha et al.   JOURNAL OF NEUROCHEMISTRY

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

(2014) Shawn A Mahmud et al.   NATURE IMMUNOLOGY

Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes

(2013) Ting-Yan Shi et al.   CARCINOGENESIS

Enhanced Atherosclerosis in TIPE2-Deficient Mice Is Associated with Increased Macrophage Responses to Oxidized Low-Density Lipoprotein

(2013) Y. Lou et al.   JOURNAL OF IMMUNOLOGY

S6K1 Negatively Regulates TAK1 Activity in the Toll-Like Receptor Signaling Pathway

(2013) S. Y. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1

(2013) Xuelei Cao et al.   Molecular Cancer

Lys48-linked TAK1 polyubiquitination at lysine-72 downregulates TNFα-induced NF-κB activation via mediating TAK1 degradation

(2012) Yihui Fan et al.   CELLULAR SIGNALLING

O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

(2012) Shalini Pathak et al.   EMBO JOURNAL

TIPE2, a Novel Regulator of Immunity, Protects against Experimental Stroke

(2012) Yan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Anti-inflammatory TIPE2 Is an Inhibitor of the Oncogenic Ras

(2012) Yael Gus-Brautbar et al.   MOLECULAR CELL

Tumor Necrosis Factor-α Induced Protein 8 Polymorphism and Risk of Non-Hodgkin’s Lymphoma in a Chinese Population: A Case-Control Study

(2012) Yan Zhang et al.   PLoS One

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

The TIPE (TNFAIP8) family in inflammation, immunity, and cancer

(2011) Yunwei Lou et al.   MOLECULAR IMMUNOLOGY

Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration

(2010) Denise M. Ray et al.   Biochemistry and Cell Biology

Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy

(2010) Shuya Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation

(2010) J.-M. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A critical role of TAK1 in B-cell receptor–mediated nuclear factor κB activation

(2009) James Schuman et al.   BLOOD

Tnfaip8 is an essential gene for the regulation of glucocorticoid-mediated apoptosis of thymocytes

(2009) M J Woodward et al.   CELL DEATH AND DIFFERENTIATION

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

TAK1 is an essential regulator of BMP signalling in cartilage

(2009) Jae-Hyuck Shim et al.   EMBO JOURNAL

Comprehending the complex connection between PKCβ, TAK1, and IKK in BCR signaling

(2009) Hisaaki Shinohara et al.   IMMUNOLOGICAL REVIEWS

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis

(2008) Honghong Sun et al.   CELL

SOCS-3 Inhibits E2F/DP-1 Transcriptional Activity and Cell Cycle Progression via Interaction with DP-1

(2008) Yoshikazu Masuhiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Phosphatase 2A Is a Negative Regulator of Transforming Growth Factor-β1-induced TAK1 Activation in Mesangial Cells

(2008) Sung Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY

TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL

(2008) Matthew C. Walsh et al.   PLoS One