New Mechanistic Insights into Purine Biosynthesis with Second Messenger c-di-AMP in Relation to Biofilm-Related Persistent Methicillin-Resistant Staphylococcus aureus Infections

The stringent response contributes to persistent methicillin-resistant Staphylococcus aureus endovascular infection through the purine biosynthetic pathway

(2020) Liang Li et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of the Novel Prophage ϕSA169 on Persistent Methicillin-Resistant Staphylococcus aureus Endovascular Infection

(2020) Liang Li et al.   mSystems

The Second Messenger c-di-AMP Regulates Diverse Cellular Pathways Involved in Stress Response, Biofilm Formation, Cell Wall Homeostasis, SpeB Expression, and Virulence in Streptococcus pyogenes

(2019) Tazin Fahmi et al.   INFECTION AND IMMUNITY

Cyclic di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation inStaphylococcus aureusbut dispensable for viability in anaerobic conditions

(2018) Merve S. Zeden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Purine Biosynthesis in Persistent Methicillin-Resistant Staphylococcus aureus (MRSA) Infection

(2018) Liang Li et al.   JOURNAL OF INFECTIOUS DISEASES

Genome-wide screen for genes involved in eDNA release during biofilm formation byStaphylococcus aureus

(2017) Alicia S. DeFrancesco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epic Immune Battles of History: Neutrophils vs. Staphylococcus aureus

(2017) Fermin E. Guerra et al.   Frontiers in Cellular and Infection Microbiology

Wall teichoic acids mediate increased virulence in Staphylococcus aureus

(2017) Stefanie Wanner et al.   Nature Microbiology

Cyclic di-AMP Released from Staphylococcus aureus Biofilm Induces a Macrophage Type I Interferon Response

(2016) Casey M. Gries et al.   INFECTION AND IMMUNITY

New Insights into the Cyclic Di-adenosine Monophosphate (c-di-AMP) Degradation Pathway and the Requirement of the Cyclic Dinucleotide for Acid Stress Resistance inStaphylococcus aureus

(2016) Lisa Bowman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biofilms and Cyclic di-GMP (c-di-GMP) Signaling: Lessons fromPseudomonas aeruginosaand Other Bacteria

(2016) Martina Valentini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Global RegulonsarARegulates β-Lactam Antibiotic Resistance in Methicillin-ResistantStaphylococcus aureusIn Vitro and in Endovascular Infections

(2016) Liang Li et al.   JOURNAL OF INFECTIOUS DISEASES

Cross-talk between Two Nucleotide-signaling Pathways inStaphylococcus aureus

(2015) Rebecca M. Corrigan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic di-AMP mediates biofilm formation

(2015) Xian Peng et al.   MOLECULAR MICROBIOLOGY

Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR

(2015) Joseph A. H. Romaniuk et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

SaeRS-Dependent Inhibition of Biofilm Formation in Staphylococcus aureus Newman

(2015) David Cue et al.   PLoS One

Inactivation of the Autolysis-Related Genes lrgB and yycI in Staphylococcus aureus Increases Cell Lysis-Dependent eDNA Release and Enhances Biofilm Development In Vitro and In Vivo

(2015) Cristiana Ossaille Beltrame et al.   PLoS One

The effect of skin fatty acids on Staphylococcus aureus

(2014) Yvonne Neumann et al.   ARCHIVES OF MICROBIOLOGY

Impact of Vancomycin on sarA-Mediated Biofilm Formation: Role in Persistent Endovascular Infections Due to Methicillin-Resistant Staphylococcus aureus

(2014) Wessam Abdelhady et al.   JOURNAL OF INFECTIOUS DISEASES

Detection of cyclic di-AMP using a competitive ELISA with a unique pneumococcal cyclic di-AMP binding protein

(2014) Adam J. Underwood et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Deletion of the cyclic di-AMP phosphodiesterase gene (cnpB) inMycobacterium tuberculosisleads to reduced virulence in a mouse model of infection

(2014) Jun Yang et al.   MOLECULAR MICROBIOLOGY

Biosynthesis of the Unique Wall Teichoic Acid of Staphylococcus aureus Lineage ST395

(2014) V. Winstel et al.   mBio

Wall Teichoic Acids of Gram-Positive Bacteria

(2013) Stephanie Brown et al.   Annual Review of Microbiology

Reduced Vancomycin Susceptibility in anIn VitroCatheter-Related Biofilm Model Correlates with Poor Therapeutic Outcomes in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

(2013) Wessam Abdelhady et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Release of extracellular ATP by bacteria during growth

(2013) Roberto Mempin et al.   BMC MICROBIOLOGY

Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence

(2013) Y. Bai et al.   JOURNAL OF BACTERIOLOGY

Cyclic Di-AMP Impairs Potassium Uptake Mediated by a Cyclic Di-AMP Binding Protein in Streptococcus pneumoniae

(2013) Y. Bai et al.   JOURNAL OF BACTERIOLOGY

Alternative Mutational Pathways to Intermediate Resistance to Vancomycin in Methicillin-Resistant Staphylococcus aureus

(2013) Celine Vidaillac et al.   JOURNAL OF INFECTIOUS DISEASES

Mutation in the C-Di-AMP Cyclase dacA Affects Fitness and Resistance of Methicillin Resistant Staphylococcus aureus

(2013) Vanina Dengler et al.   PLoS One

ABC Transporters Required for Export of Wall Teichoic Acids Do Not Discriminate between Different Main Chain Polymers

(2011) Kathrin Schirner et al.   ACS Chemical Biology

Relationship ofagrExpression and Function with Virulence and Vancomycin Treatment Outcomes in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

(2011) Kati Seidl et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Role of bacterial components in macrophage activation by the LAC and MW2 strains of community-associated, methicillin-resistant Staphylococcus aureus

(2011) Thomas Spentzas et al.   CELLULAR IMMUNOLOGY

Listeria monocytogenes tyrosine phosphatases affect wall teichoic acid composition and phage resistance

(2011) Ran Nir-Paz et al.   FEMS MICROBIOLOGY LETTERS

Deletion of  54 (rpoN) Alters the Rate of Autolysis and Biofilm Formation in Enterococcus faecalis

(2011) V. S. Iyer et al.   JOURNAL OF BACTERIOLOGY

Staphylococcus aureus CidA and LrgA Proteins Exhibit Holin-Like Properties

(2011) D. K. Ranjit et al.   JOURNAL OF BACTERIOLOGY

c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress

(2011) Rebecca M. Corrigan et al.   PLoS Pathogens

Combinatorial Phenotypic Signatures Distinguish Persistent from Resolving Methicillin-ResistantStaphylococcus aureusBacteremia Isolates

(2010) Kati Seidl et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

ADP-Glo: A Bioluminescent and Homogeneous ADP Monitoring Assay for Kinases

(2010) Hicham Zegzouti et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

The Staphylococcus aureus LytSR Two-Component Regulatory System Affects Biofilm Formation

(2009) B. K. Sharma-Kuinkel et al.   JOURNAL OF BACTERIOLOGY

Modulation of eDNA Release and Degradation Affects Staphylococcus aureus Biofilm Maturation

(2009) Ethan E. Mann et al.   PLoS One

Structural biology of the purine biosynthetic pathway

(2008) Y. Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Staphylococcal GGDEF Domain Protein Regulates Biofilm Formation Independently of Cyclic Dimeric GMP

(2008) L. M. Holland et al.   JOURNAL OF BACTERIOLOGY

Phenotypic and Genotypic Characteristics of Persistent Methicillin‐ResistantStaphylococcus aureusBacteremia In Vitro and in an Experimental Endocarditis Model

(2008) Yan Q. Xiong et al.   JOURNAL OF INFECTIOUS DISEASES

Great Times for Small Molecules: c-di-AMP, a Second Messenger Candidate in Bacteria and Archaea

(2008) U. Romling   Science Signaling