Influence of SARS-CoV-2 on airway mucus production: A review and proposed model

Anthropogenic Infection of Cats during the 2020 COVID-19 Pandemic

(2021) Margaret J. Hosie et al.   Viruses-Basel

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

(2021) Kathryn A. Ryan et al.   Nature Communications

Predicting mammalian species at risk of being infected by SARS-CoV-2 from an ACE2 perspective

(2021) Yulong Wei et al.   Scientific Reports

Impact of Race and Socioeconomic Status on Outcomes in Patients Hospitalized with COVID-19

(2021) Daniel Quan et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Antihistamines and azithromycin as a treatment for COVID-19 on primary health care – A retrospective observational study in elderly patients

(2021) Juan Ignacio Morán Blanco et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Recognizing the Clinical Sequelae of COVID-19 in Adults: COVID-19 Long-Haulers

(2021) Sherry Leviner   JNP-Journal for Nurse Practitioners

Secondary bacterial infection in COVID-19 patients is a stronger predictor for death compared to influenza patients

(2021) Noa Shafran et al.   Scientific Reports

Evolving challenges to model human diseases for translational research

(2020) Amanda P. Beck et al.   CELL AND TISSUE RESEARCH

Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry

(2020) Milena Gianfrancesco et al.   ANNALS OF THE RHEUMATIC DISEASES

Infection and Rapid Transmission of SARS-CoV-2 in Ferrets

(2020) Young-Il Kim et al.   Cell Host & Microbe

Post‐mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction

(2020) T. Menter et al.   HISTOPATHOLOGY

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters

(2020) Sin Fun Sia et al.   NATURE

Bronchiolitis and Bronchiolar Disorders

(2020) Claudia Ravaglia et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Innate Type 2 Responses to Respiratory Syncytial Virus Infection

(2020) Allison E. Norlander et al.   Viruses-Basel

Characterization of the Inflammatory Response to Severe COVID-19 Illness

(2020) Oliver J McElvaney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment

(2020) Jing Sun et al.   CELL

Elevated MUC1 and MUC5AC mucin protein levels in airway mucus of critical ill COVID‐19 Patients

(2020) Wenju Lu et al.   JOURNAL OF MEDICAL VIROLOGY

Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study

(2020) Luca Carsana et al.   LANCET INFECTIOUS DISEASES

Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

(2020) Raphaël Cauchois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Unrecognized Threat of Secondary Bacterial Infections with COVID-19

(2020) Mylene Vaillancourt et al.   mBio

Single-cell analysis reveals bronchoalveolar epithelial dysfunction in COVID-19 patients

(2020) Jiangping He et al.   Protein & Cell

Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients

(2020) Chaofu Wang et al.   EBioMedicine

Secondary Infections in Patients Hospitalized with COVID-19: Incidence and Predictive Factors

(2020) Marco Ripa et al.   CLINICAL MICROBIOLOGY AND INFECTION

COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City

(2020) Alain C. Borczuk et al.   MODERN PATHOLOGY

Animal models for COVID-19

(2020) César Muñoz-Fontela et al.   NATURE

An inflammatory cytokine signature predicts COVID-19 severity and survival

(2020) Diane Marie Del Valle et al.   NATURE MEDICINE

Characteristics of SARS-CoV-2 and COVID-19

(2020) Ben Hu et al.   NATURE REVIEWS MICROBIOLOGY

Association of cardiovascular disease and 10 other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis

(2020) Paddy Ssentongo et al.   PLoS One

Pigs are not susceptible to SARS‐CoV‐2 infection but are a model for viral immunogenicity studies

(2020) Júlia Vergara‐Alert et al.   Transboundary and Emerging Diseases

Lack of airway submucosal glands impairs respiratory host defenses

(2020) Lynda S Ostedgaard et al.   eLife

Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis

(2020) Jarbas da Silva Motta Junior et al.   Frontiers in Immunology

Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants

(2020) Gayatri R. Iyer et al.   Frontiers in Genetics

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

(2020) Miguel E. Ortiz et al.   EBioMedicine

Identification of antiviral antihistamines for COVID-19 repurposing

(2020) Leah R. Reznikov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Assessment of Racial/Ethnic Disparities in Hospitalization and Mortality in Patients With COVID-19 in New York City

(2020) Gbenga Ogedegbe et al.   JAMA Network Open

The Role of Histamine in the Pathophysiology of Asthma and the Clinical Efficacy of Antihistamines in Asthma Therapy

(2019) Kohei Yamauchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis

(2019) Gang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

The Family of Chloride Channel Regulator, Calcium-activated Proteins in the Feline Respiratory Tract: A Comparative Perspective on Airway Diseases in Man and Animal Models

(2019) N.A. Erickson et al.   JOURNAL OF COMPARATIVE PATHOLOGY

MUC5B Promoter Polymorphism and Development of ARDS

(2018) Angela J Rogers et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction

(2018) Eleanor M. Dunican et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Histamine and Histamine Receptors in Mast Cell-Mediated Allergy and Inflammation: The Hunt for New Therapeutic Targets

(2018) Elden Berla Thangam et al.   Frontiers in Immunology

The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes

(2017) Rachel K. Putman et al.   EUROPEAN RESPIRATORY JOURNAL

Brief mechanical ventilation causes differential epithelial repair along the airways of fetal, preterm lambs

(2016) Nicole Deputla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Acidic pH increases airway surface liquid viscosity in cystic fibrosis

(2016) Xiao Xiao Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

Airway acidification initiates host defense abnormalities in cystic fibrosis mice

(2016) V. S. Shah et al.   SCIENCE

Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice

(2016) Leah R. Reznikov et al.   PLoS One

Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans

(2015) David K. Meyerholz et al.   TOXICOLOGIC PATHOLOGY

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

(2015) Christopher M. Evans et al.   Nature Communications

The role for human nasal epithelial nuclear factor kappa B activation in histamine-induced mucin 5 subtype B overproduction

(2015) Weiwei Wang et al.   International Forum of Allergy & Rhinology

Critical Role for the NLRP3 Inflammasome during Acute Lung Injury

(2014) J. J. Grailer et al.   JOURNAL OF IMMUNOLOGY

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis

(2014) M. J. Hoegger et al.   SCIENCE

The Respiratory Syncytial Virus Fusion Protein and Neutrophils Mediate the Airway Mucin Response to Pathogenic Respiratory Syncytial Virus Infection

(2013) K. L. Stokes et al.   JOURNAL OF VIROLOGY

Muc5b is required for airway defence

(2013) Michelle G. Roy et al.   NATURE

P. aeruginosa Lipopolysaccharide-Induced MUC5AC and CLCA3 Expression Is Partly through Duox1 In Vitro and In Vivo

(2013) Wen Li et al.   PLoS One

Supramolecular Dynamics of Mucus

(2013) P. Verdugo   Cold Spring Harbor Perspectives in Medicine

Structure and Function of the Mucus Clearance System of the Lung

(2013) B. M. Button et al.   Cold Spring Harbor Perspectives in Medicine

Histopathologic and Morphometric Evaluation of the Nasal and Pulmonary Airways of Cats with Experimentally Induced Asthma

(2012) Christine M. Venema et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury

(2012) M Koeppen et al.   Mucosal Immunology

Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs

(2012) C. Ehre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR signaling in mast cells: common and unique features

(2012) Hilary Sandig et al.   Frontiers in Immunology

The ferret as a model organism to study influenza A virus infection

(2011) J. A. Belser et al.   Disease Models & Mechanisms

A CommonMUC5BPromoter Polymorphism and Pulmonary Fibrosis

(2011) Max A. Seibold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of Airway MUC5AC Expression by IL-1  and IL-17A; the NF- B Paradigm

(2009) T. Fujisawa et al.   JOURNAL OF IMMUNOLOGY

The porcine lung as a potential model for cystic fibrosis

(2008) Christopher S. Rogers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MUC5B Is the Major Mucin in the Gel Phase of Sputum in Chronic Obstructive Pulmonary Disease

(2008) Sara Kirkham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mucus hypersecretion in asthma: causes and effects

(2008) Christopher M Evans et al.   CURRENT OPINION IN PULMONARY MEDICINE

Adeno-associated virus–targeted disruption of the CFTR gene in cloned ferrets

(2008) Xingshen Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

The non-human primate as a model for studying COPD and asthma

(2008) Charles G. Plopper et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS