Photoactivated Self‐Disassembly of Multifunctional DNA Nanoflower Enables Amplified Autophagy Suppression for Low‐Dose Photodynamic Therapy

The effector mechanism of siRNA spherical nucleic acids

(2020) Gokay Yamankurt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging small molecule-induced endosomal escape of siRNA

(2020) Hampus Du Rietz et al.   Nature Communications

A smart theranostic nanocapsule for spatiotemporally programmable photo‐genetherapy

(2020) Xue Gong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photodynamic therapy: autophagy and mitophagy, apoptosis and paraptosis

(2020) David Kessel et al.   Autophagy

MicroRNA-responsive release of Cas9/sgRNA from DNA nanoflower for cytosolic protein delivery and enhanced genome editing

(2020) Jinjin Shi et al.   BIOMATERIALS

Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism

(2020) Cassidy C. Daw et al.   CELL

Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche

(2020) Marvin Krohn-Grimberghe et al.   Nature Biomedical Engineering

An ATP-Regulated Ion Transport Nanosystem for Homeostatic Perturbation Therapy and Sensitizing Photodynamic Therapy by Autophagy Inhibition of Tumors

(2019) Shuang-Shuang Wan et al.   ACS Central Science

Engineering of Bioinspired, Size-Controllable, Self-Degradable Cancer-Targeting DNA Nanoflowers via the Incorporation of an Artificial Sandwich Base

(2019) Lili Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNAzyme-Loading MOFs for Self-Sufficient Gene Therapy

(2019) Huimin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonviolent Self-Catabolic DNAzyme Nanosponges for Smart Anticancer Drug Delivery

(2019) Jing Wang et al.   ACS Nano

A Mesoporous Nanoenzyme Derived from Metal–Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy

(2019) Dongdong Wang et al.   ADVANCED MATERIALS

Photoactivated Lysosomal Escape of a Monofunctional PtII Complex Pt-BDPA for Nucleus Access

(2019) Xuling Xue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor Antigen Mediated Conformational Changes of Nanoplatform for Activated Photodynamic Therapy

(2019) Junjie Liu et al.   Advanced Healthcare Materials

DNA Nanosponge for Adsorption and Clearance of Intracellular miR-21 and Enhanced Antitumor Chemotherapy

(2019) Kaixiang Zhang et al.   ACS Applied Materials & Interfaces

Rolling circle amplification for single cell analysis and in situ sequencing

(2019) Hua Gao et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Innovative Strategies for Hypoxic-Tumor Photodynamic Therapy

(2018) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gene therapy comes of age

(2018) Cynthia E. Dunbar et al.   SCIENCE

A self-destructive nanosweeper that captures and clears amyloid β-peptides

(2018) Qiang Luo et al.   Nature Communications

A Cascade-Targeting Nanocapsule for Enhanced Photothermal Tumor Therapy with Aid of Autophagy Inhibition

(2018) Xilong Wu et al.   Advanced Healthcare Materials

Blocking Autophagic Flux Enhances Iron Oxide Nanoparticle Photothermal Therapeutic Efficiency in Cancer Treatment

(2018) Xiaoqing Ren et al.   ACS Applied Materials & Interfaces

Self-Assembled Minimalist Multifunctional Theranostic Nanoplatform for Magnetic Resonance Imaging-Guided Tumor Photodynamic Therapy

(2018) Han Zhang et al.   ACS Nano

Emerging Applications of Nanotechnology for Controlling Cell-Surface Receptor Clustering

(2018) Kaixiang Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis

(2018) Shashank Rai et al.   Autophagy

DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

(2018) Dawei Jiang et al.   Nature Biomedical Engineering

Reversible control of cell membrane receptor function using DNA nano-spring multivalent ligands

(2017) Kaixiang Zhang et al.   Chemical Science

Biodegradable, multifunctional DNAzyme nanoflowers for enhanced cancer therapy

(2017) Yi Jin et al.   NPG Asia Materials

Theranostic DNAzymes

(2017) Wenhu Zhou et al.   Theranostics

Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions

(2017) Demian van Straten et al.   Cancers

Overcoming the Achilles' heel of photodynamic therapy

(2016) Wenpei Fan et al.   CHEMICAL SOCIETY REVIEWS

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Hierarchical Plasmonic Nanorods and Upconversion Core-Satellite Nanoassemblies for Multimodal Imaging-Guided Combination Phototherapy

(2015) Maozhong Sun et al.   ADVANCED MATERIALS

A Smart DNAzyme-MnO2Nanosystem for Efficient Gene Silencing

(2015) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrathin Black Phosphorus Nanosheets for Efficient Singlet Oxygen Generation

(2015) Hui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of autophagy enhances the anticancer activity of silver nanoparticles

(2014) Jun Lin et al.   Autophagy

Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells

(2014) Ming-Feng Wei et al.   Autophagy

Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine

(2014) M. Monsur Ali et al.   CHEMICAL SOCIETY REVIEWS

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

(2014) Vladimir P. Torchilin   NATURE REVIEWS DRUG DISCOVERY

Triplet photosensitizers: from molecular design to applications

(2013) Jianzhang Zhao et al.   CHEMICAL SOCIETY REVIEWS

Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications

(2013) Guizhi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5

(2012) Dong-Yun Ouyang et al.   Autophagy

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy

(2012) Chinatsu Otomo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy

(2011) Microsugar Chang et al.   ACS Nano

Self-Assembly of a Bifunctional DNA Carrier for Drug Delivery

(2011) Kelong Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Apoptotic and autophagic responses to photodynamic therapy in 1c1c7 murine hepatoma cells

(2011) Michelle Andrzejak et al.   Autophagy

Bio-inspired, bioengineered and biomimetic drug delivery carriers

(2011) Jin-Wook Yoo et al.   NATURE REVIEWS DRUG DISCOVERY

Assessing autophagy in the context of photodynamic therapy

(2010) John J. Reiners et al.   Autophagy