Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine

Simple Design for DNA Nanotubes from a Minimal Set of Unmodified Strands: Rapid, Room-Temperature Assembly and Readily Tunable Structure

(2013) Graham D. Hamblin et al.   ACS Nano

Bead-based padlock rolling circle amplification for single DNA molecule counting

(2013) Kae Sato et al.   ANALYTICAL BIOCHEMISTRY

A polyvalent aptamer system for targeted drug delivery

(2013) Zhiqing Zhang et al.   BIOMATERIALS

A chemiluminescence imaging array for the detection of cancer cells by dual-aptamer recognition and bio-bar-code nanoprobe-based rolling circle amplification

(2013) Sai Bi et al.   CHEMICAL COMMUNICATIONS

Hybridization chain reaction-based branched rolling circle amplification for chemiluminescence detection of DNA methylation

(2013) Sai Bi et al.   CHEMICAL COMMUNICATIONS

Fluorescence Imaging of Single-Copy DNA Sequences within the Human Genome Using PNA-Directed Padlock Probe Assembly

(2013) Anastasia I. Yaroslavsky et al.   CHEMISTRY & BIOLOGY

DNA nanotechnology with one-dimensional self-assembled nanostructures

(2013) Fuan Wang et al.   CURRENT OPINION IN BIOTECHNOLOGY

Turning a Kinase Deoxyribozyme into a Sensor

(2013) Simon A. McManus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RCA Strands as Scaffolds To Create Nanoscale Shapes by a Few Staple Strands

(2013) Yinzhou Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification

(2013) Xiangyuan Ouyang et al.   METHODS

Single Cell MicroRNA Analysis Using Microfluidic Flow Cytometry

(2013) Meiye Wu et al.   PLoS One

Gold Nanoparticle 3D-DNA Building Blocks: High Purity Preparation and Use for Modular Access to Nanoparticle Assemblies

(2013) Kai Lin Lau et al.   Small

Carbon Nanotubes Multifunctionalized by Rolling Circle Amplification and Their Application for Highly Sensitive Detection of Cancer Markers

(2013) Bin Zhao et al.   Small

Rolling Circle Amplification-Based DNA Origami Nanostructrures for Intracellular Delivery of Immunostimulatory Drugs

(2013) Xiangyuan Ouyang et al.   Small

DNA-directed self-assembly of shape-controlled hydrogels

(2013) Hao Qi et al.   Nature Communications

Droplet Microfluidics Platform for Highly Sensitive and Quantitative Detection of Malaria-Causing Plasmodium Parasites Based on Enzyme Activity Measurement

(2012) Sissel Juul et al.   ACS Nano

Detection of Antigens Using a Protein–DNA Chimera Developed by Enzymatic Covalent Bonding with phiX Gene A*

(2012) Farhima Akter et al.   ANALYTICAL CHEMISTRY

Colorimetric and Ultrasensitive Bioassay Based on a Dual-Amplification System Using Aptamer and DNAzyme

(2012) Longhua Tang et al.   ANALYTICAL CHEMISTRY

Sensitive and Label-Free DNA Methylation Detection by Ligation-Mediated Hyperbranched Rolling Circle Amplification

(2012) Anping Cao et al.   ANALYTICAL CHEMISTRY

Ultrasensitive Electrochemical Detection of Nucleic Acids by Template Enhanced Hybridization Followed with Rolling Circle Amplification

(2012) Hanxu Ji et al.   ANALYTICAL CHEMISTRY

DNAzyme-Based Rolling-Circle Amplification DNA Machine for Ultrasensitive Analysis of MicroRNA in Drosophila Larva

(2012) Yanqin Wen et al.   ANALYTICAL CHEMISTRY

Direct labeling rolling circle amplification as a straightforward signal amplification technique for biodetection formats

(2012) Lena Linck et al.   Analytical Methods

Sensitive Detection of Proteins Using Assembled Cascade Fluorescent DNA Nanotags Based on Rolling Circle Amplification

(2012) Qingwang Xue et al.   BIOCONJUGATE CHEMISTRY

Ultrasensitive electrochemical immunosensor for HE4 based on rolling circle amplification

(2012) Lingsong Lu et al.   BIOSENSORS & BIOELECTRONICS

Highly sensitive and selective chemiluminescent imaging for DNA detection by ligation-mediated rolling circle amplified synthesis of DNAzyme

(2012) Haifeng Dong et al.   BIOSENSORS & BIOELECTRONICS

A target-activated autocatalytic DNAzyme amplification strategy for the assay of base excision repair enzyme activity

(2012) Liangliang Zhang et al.   CHEMICAL COMMUNICATIONS

Cascade signal amplification strategy for the detection of cancer cells by rolling circle amplification and nanoparticles tagging

(2012) Caifeng Ding et al.   CHEMICAL COMMUNICATIONS

Whole genome amplification of degraded and nondegraded DNA for forensic purposes

(2012) Agnieszka Maciejewska et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

My Life with Bacteriophage φ29

(2012) Margarita Salas   JOURNAL OF BIOLOGICAL CHEMISTRY

Rolling Circle Amplification-Templated DNA Nanotubes Show Increased Stability and Cell Penetration Ability

(2012) Graham D. Hamblin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

A mechanical metamaterial made from a DNA hydrogel

(2012) Jong Bum Lee et al.   Nature Nanotechnology

Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation

(2012) Gucci Jijuan Gu et al.   New Biotechnology

Candidate RNA structures for domain 3 of the foot-and-mouth-disease virus internal ribosome entry site

(2012) Segun Jung et al.   NUCLEIC ACIDS RESEARCH

Amplified microRNA detection by templated chemistry

(2012) Emily M. Harcourt et al.   NUCLEIC ACIDS RESEARCH

Rapid Identification of Bio-Molecules Applied for Detection of Biosecurity Agents Using Rolling Circle Amplification

(2012) Jenny Göransson et al.   PLoS One

Selective Enrichment and Sequencing of Whole Mitochondrial Genomes in the Presence of Nuclear Encoded Mitochondrial Pseudogenes (Numts)

(2012) Jonci N. Wolff et al.   PLoS One

Bioinspired multivalent DNA network for capture and release of cells

(2012) W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensitive Detection of Spores Using Volume-Amplified Magnetic Nanobeads

(2012) Teresa Zardán Gómez de la Torre et al.   Small

Ultrasensitive Colorimetric DNA Detection using a Combination of Rolling Circle Amplification and Nicking Endonuclease-Assisted Nanoparticle Amplification (NEANA)

(2012) Wei Xu et al.   Small

Stimuli-responsive organization of block copolymers on DNA nanotubes

(2012) Karina M. M. Carneiro et al.   Chemical Science

Detection of Single Enzymatic Events in Rare or Single Cells Using Microfluidics

(2011) Sissel Juul et al.   ACS Nano

Detection of small RNA molecules by a combination of branched rolling circle amplification and bioluminescent pyrophosphate assay

(2011) Yasumasa Mashimo et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Immuno-rolling circle amplification using a multibinding fusion protein

(2011) Farhima Akter et al.   ANALYTICAL BIOCHEMISTRY

Ultrasensitive Multiplexed MicroRNA Quantification on Encoded Gel Microparticles Using Rolling Circle Amplification

(2011) Stephen C. Chapin et al.   ANALYTICAL CHEMISTRY

Ferrocenemonocarboxylic–HRP@Pt nanoparticles labeled RCA for multiple amplification of electro-immunosensing

(2011) Huilan Su et al.   BIOSENSORS & BIOELECTRONICS

Cocaine detection via rolling circle amplification of short DNA strand separated by magnetic beads

(2011) Cuiping Ma et al.   BIOSENSORS & BIOELECTRONICS

Modulation of DNA-Modified Gold-Nanoparticle Stability in Salt with Concatemeric Single-Stranded DNAs for Colorimetric Bioassay Development

(2011) M. Monsur Ali et al.   CHEMISTRY-A EUROPEAN JOURNAL

Integration of rolling circle amplification and cationic conjugated polymer for the homogeneous detection of single nucleotide polymorphisms

(2011) ZhiYuan Tang et al.   CHINESE SCIENCE BULLETIN

Quantitation of HBV covalently closed circular DNA in micro formalin fixed paraffin-embedded liver tissue using rolling circle amplification in combination with real-time PCR

(2011) Yanwei Zhong et al.   CLINICA CHIMICA ACTA

Analysis of CpG Island Methylation Using Rolling Circle Amplification (RCA) Product Microarray

(2011) Hong Zhao et al.   Journal of Biomedical Nanotechnology

Conformation-Selective Methylation of Geminivirus DNA

(2011) T. Paprotka et al.   JOURNAL OF VIROLOGY

Sensitive RNA detection by combining three-way junction formation and primer generation-rolling circle amplification

(2011) Taku Murakami et al.   NUCLEIC ACIDS RESEARCH

Targeted Cell-Cell Interactions by DNA Nanoscaffold-Templated Multivalent Bispecific Aptamers

(2011) Xiaowei Liu et al.   Small

Direct detection of green fluorescent protein messenger RNA expressed in Escherichia coli by rolling circle amplification

(2010) Hirokazu Takahashi et al.   ANALYTICAL BIOCHEMISTRY

Universal Aptameric System for Highly Sensitive Detection of Protein Based on Structure-Switching-Triggered Rolling Circle Amplification

(2010) Zai-Sheng Wu et al.   ANALYTICAL CHEMISTRY

Rolling Circle Amplification Combined with Gold Nanoparticle Aggregates for Highly Sensitive Identification of Single-Nucleotide Polymorphisms

(2010) Jishan Li et al.   ANALYTICAL CHEMISTRY

Cascade Signal Amplification Strategy for Subattomolar Protein Detection by Rolling Circle Amplification and Quantum Dots Tagging

(2010) Wei Cheng et al.   ANALYTICAL CHEMISTRY

In situ detection and genotyping of individual mRNA molecules

(2010) Chatarina Larsson et al.   NATURE METHODS

A dumbbell probe-mediated rolling circle amplification strategy for highly sensitive microRNA detection

(2010) Yuntao Zhou et al.   NUCLEIC ACIDS RESEARCH

A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia

(2010) Prabodhika R. Mallikaratchy et al.   NUCLEIC ACIDS RESEARCH

Direct detection of RNA in vitro and in situ by target-primed RCA: The impact of E. coli RNase III on the detection efficiency of RNA sequences distanced far from the 3'-end

(2010) E. Merkiene et al.   RNA

Ultrasensitive Detection of Low-Abundance Surface-Marker Protein Using Isothermal Rolling Circle Amplification in a Microfluidic Nanoliter Platform

(2010) Tania Konry et al.   Small

An On-Nanoparticle Rolling-Circle Amplification Platform for Ultrasensitive Protein Detection in Biological Fluids

(2010) Juan Yan et al.   Small

Single-stranded DNA binding protein facilitates specific enrichment of circular DNA molecules using rolling circle amplification

(2009) Tsutomu Mikawa et al.   ANALYTICAL BIOCHEMISTRY

Attomole DNA detection assay via rolling circle amplification and single molecule detection

(2009) Eric Schopf et al.   ANALYTICAL BIOCHEMISTRY

Multiplex Detection of DNA Sequences Using the Volume-Amplified Magnetic Nanobead Detection Assay

(2009) Mattias Strömberg et al.   ANALYTICAL CHEMISTRY

Microsphere-Based Rolling Circle Amplification Microarray for the Detection of DNA and Proteins in a Single Assay

(2009) Tania Konry et al.   ANALYTICAL CHEMISTRY

Stand-Alone Rolling Circle Amplification Combined with Capillary Electrophoresis for Specific Detection of Small RNA

(2009) Ni Li et al.   ANALYTICAL CHEMISTRY

DNA Encapsulating Liposome Based Rolling Circle Amplification Immunoassay as a Versatile Platform for Ultrasensitive Detection of Protein

(2009) Li-Juan Ou et al.   ANALYTICAL CHEMISTRY

Diffractometric Detection of Proteins Using Microbead-Based Rolling Circle Amplification

(2009) Joonhyung Lee et al.   ANALYTICAL CHEMISTRY

Colorimetric Sensing by Using Allosteric-DNAzyme-Coupled Rolling Circle Amplification and a Peptide Nucleic Acid-Organic Dye Probe

(2009) M. Monsur Ali et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Sensitive Determination of microRNA Using Target-Primed and Branched Rolling-Circle Amplification

(2009) Yongqiang Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A label-free strategy for SNP detection with high fidelity and sensitivity based on ligation-rolling circle amplification and intercalating of methylene blue

(2009) Songbai Zhang et al.   BIOSENSORS & BIOELECTRONICS

Magnetic beads based rolling circle amplification–electrochemiluminescence assay for highly sensitive detection of point mutation

(2009) Qiang Su et al.   BIOSENSORS & BIOELECTRONICS

Cell-free cloning using multiply-primed rolling circle amplification with modified RNA primers

(2009) Hirokazu Takahashi et al.   BIOTECHNIQUES

Rolling-Circle Amplification: Unshared Advantages in miRNA Detection

(2009) Saskia Neubacher et al.   CHEMBIOCHEM

Detection of DNA using bioactive paper strips

(2009) M. Monsur Ali et al.   CHEMICAL COMMUNICATIONS

Endonuclease-rolling circle amplification-based method for sensitive analysis of DNA-binding protein

(2009) Min Li Li et al.   CHINESE CHEMICAL LETTERS

Self-Assembly of Enzymes on DNA Scaffolds: En Route to Biocatalytic Cascades and the Synthesis of Metallic Nanowires

(2009) Ofer I. Wilner et al.   NANO LETTERS

Rolling-circle amplification of viral DNA genomes using phi29 polymerase

(2009) Reimar Johne et al.   TRENDS IN MICROBIOLOGY

Single-Molecule Detection of Human Topoisomerase I Cleavage−Ligation Activity

(2008) Magnus Stougaard et al.   ACS Nano

Homogeneous and label-free bioluminescence detection of single nucleotide polymorphism with rolling circle amplification

(2008) Yongqiang Cheng et al.   ANALYST

Homogeneous and label-free fluorescence detection of single-nucleotide polymorphism using target-primed branched rolling circle amplification

(2008) Yongqiang Cheng et al.   ANALYTICAL BIOCHEMISTRY

Rolling Circle Amplification: Applications in Nanotechnology and Biodetection with Functional Nucleic Acids

(2008) Weian Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sensitive and selective viral DNA detection assay via microbead-based rolling circle amplification

(2008) Eric Schopf et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel Designs of Multivalent Anti-CD20 Humanized Antibodies as Improved Lymphoma Therapeutics

(2008) E. A. Rossi et al.   CANCER RESEARCH

Design of Gold Nanoparticle-Based Colorimetric Biosensing Assays

(2008) Weian Zhao et al.   CHEMBIOCHEM

DNAzymes for sensing, nanobiotechnology and logic gate applications

(2008) Itamar Willner et al.   CHEMICAL SOCIETY REVIEWS

Genotyping of multiple single nucleotide polymorphisms with hyperbranched rolling circle amplification and microarray

(2008) Xiujie Li et al.   CLINICA CHIMICA ACTA

Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice

(2008) James O. McNamara et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid Identification and Differentiation of Trichophyton Species, Based on Sequence Polymorphisms of the Ribosomal Internal Transcribed Spacer Regions, by Rolling-Circle Amplification

(2008) F. Kong et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sensitive Molecular Diagnostics Using Volume-Amplified Magnetic Nanobeads

(2008) Mattias Strömberg et al.   NANO LETTERS

Enzymatic signal amplification of molecular beacons for sensitive DNA detection

(2008) Jianwei Jeffery Li et al.   NUCLEIC ACIDS RESEARCH

Sensitive isothermal detection of nucleic-acid sequence by primer generation–rolling circle amplification

(2008) Taku Murakami et al.   NUCLEIC ACIDS RESEARCH

A procedure for highly specific, sensitive, and unbiased whole-genome amplification

(2008) X. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increasing the Complexity of Periodic Protein Nanostructures by the Rolling-Circle-Amplified Synthesis of Aptamers

(2007) Zoya Cheglakov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CE combined with rolling circle amplification for sensitive DNA detection

(2007) Ni Li et al.   ELECTROPHORESIS