Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne

Diet-induced obesity promotes infection by impairment of the innate antimicrobial defense function of dermal adipocyte progenitors

(2021) Ling-juan Zhang et al.   Science Translational Medicine

Inference and analysis of cell-cell communication using CellChat

(2021) Suoqin Jin et al.   Nature Communications

Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity

(2021) Andrew D. Hildreth et al.   NATURE IMMUNOLOGY

Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection

(2020) Tatsuya Dokoshi et al.   Cell Reports

The Impact of Single-Cell Genomics on Adipose Tissue Research

(2020) Alana Deutsch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis

(2020) Johann E. Gudjonsson et al.   JCI Insight

Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense

(2019) Stella X. Chen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Short-Chain Fatty Acids from Cutibacterium acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes

(2019) James A. Sanford et al.   JOURNAL OF IMMUNOLOGY

Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression

(2019) Robert M. Hughes et al.   CANCER RESEARCH

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

(2019) Joseph McLaughlin et al.   Microorganisms

Retinoids Enhance the Expression of Cathelicidin Antimicrobial Peptide during Reactive Dermal Adipogenesis

(2019) Marc C. Liggins et al.   JOURNAL OF IMMUNOLOGY

Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice

(2019) Zhuzhen Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipocalin 2 Protects Against Escherichia coli Infection by Modulating Neutrophil and Macrophage Function

(2019) Qianqian Wang et al.   Frontiers in Immunology

Leptin Induces Proadipogenic and Proinflammatory Signaling in Adipocytes

(2019) Lohanna Palhinha et al.   Frontiers in Endocrinology

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

(2018) Kelly Street et al.   BMC GENOMICS

CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy

(2018) Ryuma Tokunaga et al.   CANCER TREATMENT REVIEWS

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta

(2018) Ling-juan Zhang et al.   IMMUNITY

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Host-microbiome interactions and recent progress into understanding the biology of acne vulgaris

(2018) Alan M. O’Neill et al.   Microbiome

What is new in the pathophysiology of acne, an overview

(2017) B. Dréno   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Sebocytes differentially express and secrete adipokines

(2016) Dóra Kovács et al.   EXPERIMENTAL DERMATOLOGY

TLR-2 Recognizes Propionibacterium acnes CAMP Factor 1 from Highly Inflammatory Strains

(2016) Coralie Lheure et al.   PLoS One

Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors

(2016) Erica Miraglia et al.   Scientific Reports

Dermal adipocytes protect against invasive Staphylococcus aureus skin infection

(2015) L.-j. Zhang et al.   SCIENCE

Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer

(2015) Pamela Maris et al.   PLOS MEDICINE

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

PPARγ and the global map of adipogenesis and beyond

(2014) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Staphylococcal Superantigens Stimulate Immortalized Human Adipocytes to Produce Chemokines

(2013) Bao G. Vu et al.   PLoS One

Functions of the skin microbiota in health and disease

(2013) James A. Sanford et al.   SEMINARS IN IMMUNOLOGY

Systemic Isotretinoin Therapy Normalizes Exaggerated TLR-2-Mediated Innate Immune Responses in Acne Patients

(2012) Melanie C. Dispenza et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Transcriptional control of preadipocyte determination by Zfp423

(2010) Rana K. Gupta et al.   NATURE

RIP140 in thyroid hormone-repression and chromatin remodeling of Crabp1 gene during adipocyte differentiation

(2009) Sung Wook Park et al.   NUCLEIC ACIDS RESEARCH

PPAR  and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

(2008) M. I. Lefterova et al.   GENES & DEVELOPMENT

Neutrophil gelatinase–associated lipocalin mediates 13-cis retinoic acid–induced apoptosis of human sebaceous gland cells

(2008) Amanda M. Nelson et al.   JOURNAL OF CLINICAL INVESTIGATION

Sebocytes Express Functional Cathelicidin Antimicrobial Peptides and Can Act to Kill Propionibacterium Acnes

(2008) Dong-Youn Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Complex regulation of human cathelicidin gene expression: Novel splice variants and 5′UTR negative regulatory element

(2007) Houda Zghal Elloumi et al.   MOLECULAR IMMUNOLOGY