Diet-induced obesity promotes infection by impairment of the innate antimicrobial defense function of dermal adipocyte progenitors

Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair

(2020) Brett A. Shook et al.   Cell Stem Cell

Adipogenesis and metabolic health

(2019) Alexandra L. Ghaben et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

(2019) Christian F. Guerrero-Juarez et al.   Nature Communications

Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense

(2019) Stella X. Chen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

(2019) David Merrick et al.   SCIENCE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Potential Roles of Adiponectin Isoforms in Human Obesity with Delayed Wound Healing

(2019) Jiyoon Ryu et al.   Cells

Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice

(2019) Zhuzhen Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue

(2018) Peng Zhao et al.   CELL

Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis

(2018) Yutaka Hasegawa et al.   Cell Metabolism

Anatomical, Physiological, and Functional Diversity of Adipose Tissue

(2018) Rachel K. Zwick et al.   Cell Metabolism

Emerging nonmetabolic functions of skin fat

(2018) Christian F. Guerrero-Juarez et al.   Nature Reviews Endocrinology

A stromal cell population that inhibits adipogenesis in mammalian fat depots

(2018) Petra C. Schwalie et al.   NATURE

Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

(2018) Marcus Grohmann et al.   CELL

Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta

(2018) Ling-juan Zhang et al.   IMMUNITY

Transforming Growth Factor-β3 Regulates Adipocyte Number in Subcutaneous White Adipose Tissue

(2018) Paul Petrus et al.   Cell Reports

Regeneration of fat cells from myofibroblasts during wound healing

(2017) Maksim V. Plikus et al.   SCIENCE

The cathelicidin protein CRAMP is a potential atherosclerosis self-antigen in ApoE(-/-) mice

(2017) Peter M. Mihailovic et al.   PLoS One

Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis and wound repair

(2017) Chia-Lung Wu et al.   Scientific Reports

Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis

(2016) Guillermo C. Rivera-Gonzalez et al.   Cell Stem Cell

Antimicrobial peptides

(2016) Ling-juan Zhang et al.   CURRENT BIOLOGY

Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury

(2016) Ling-juan Zhang et al.   IMMUNITY

Non-coding Double-stranded RNA and Antimicrobial Peptide LL-37 Induce Growth Factor Expression from Keratinocytes and Endothelial Cells

(2016) Christopher A. Adase et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic cells maintain dermal adipose–derived stromal cells in skin fibrosis

(2016) Jennifer J. Chia et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis

(2016) Jean Fan et al.   NATURE METHODS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

(2015) Tomoaki Iwayama et al.   GENES & DEVELOPMENT

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity

(2015) Elise Jeffery et al.   NATURE CELL BIOLOGY

Dermal adipocytes protect against invasive Staphylococcus aureus skin infection

(2015) L.-j. Zhang et al.   SCIENCE

Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin-Positive Intradermal Progenitors

(2015) Roberta Goncalves Marangoni et al.   Arthritis & Rheumatology

Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress

(2014) Ildiko Kasza et al.   PLoS Genetics

Intradermal adipocytes mediate fibroblast recruitment during skin wound healing

(2013) B. A. Schmidt et al.   DEVELOPMENT

Distinct fibroblast lineages determine dermal architecture in skin development and repair

(2013) Ryan R. Driskell et al.   NATURE

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Multiple Immune-Modulatory Functions Of Cathelicidin Host Defense Peptides

(2012) Ka-Yee (Grace) Choi et al.   Frontiers in Immunology

Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling

(2011) Eric Festa et al.   CELL

Body Adipose Content is Independently Associated With a Higher Risk of Organ Failure and Nosocomial Infection in the Nonobese Patient Postinjury

(2011) Rebecca D. Edmonds et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

PPARγ Downregulation by TGFß in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis

(2010) Jun Wei et al.   PLoS One

Factors predisposing to acute and recurrent bacterial non-necrotizing cellulitis in hospitalized patients: a prospective case–control study

(2009) M. Karppelin et al.   CLINICAL MICROBIOLOGY AND INFECTION

Association of human cathelicidin (hCAP-18/LL-37) gene expression with cardiovascular disease risk factors

(2009) H. Benachour et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Macrophage-Secreted Factors Promote a Profibrotic Phenotype in Human Preadipocytes

(2008) Mayoura Keophiphath et al.   MOLECULAR ENDOCRINOLOGY