Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

(2015) Alexandre Calon et al.   NATURE GENETICS

MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

(2014) David S Hong et al.   LANCET ONCOLOGY

Asporin activates coordinated invasion of scirrhous gastric cancer and cancer-associated fibroblasts

(2014) R Satoyoshi et al.   ONCOGENE

Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA1) Activation in Human Breast and Prostate Cancers

(2014) Marion David et al.   PLoS One

Carcinoma-associated fibroblasts provide operational flexibility in metastasis

(2014) Olivier De Wever et al.   SEMINARS IN CANCER BIOLOGY

The Emerging Role of the Molecular Diagnostics Laboratory in Breast Cancer Personalized Medicine

(2013) Francine B. De Abreu et al.   AMERICAN JOURNAL OF PATHOLOGY

Triple-Negative Breast Cancer and the Need for New Therapeutic Targets

(2013) Olav Engebraaten et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular and Cellular Heterogeneity in Breast Cancer

(2013) Ashley G. Rivenbark et al.   AMERICAN JOURNAL OF PATHOLOGY

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Prediction Errors in Learning Drug Response from Gene Expression Data – Influence of Labeling, Sample Size, and Machine Learning Algorithm

(2013) Immanuel Bayer et al.   PLoS One

Decorin

(2012) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay

(2012) T. Fiaschi et al.   CANCER RESEARCH

Differential proteomic analysis of a human breast tumor and its matched bone metastasis identifies cell membrane and extracellular proteins associated with bone metastasis

(2012) Bruno Dumont et al.   JOURNAL OF PROTEOME RESEARCH

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

(2011) Hideaki Ijichi et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of Novel Accessible Proteins Bearing Diagnostic and Therapeutic Potential in Human Pancreatic Ductal Adenocarcinoma

(2011) Andrei Turtoi et al.   JOURNAL OF PROTEOME RESEARCH

Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate

(2011) B Orr et al.   ONCOGENE

GOBO: Gene Expression-Based Outcome for Breast Cancer Online

(2011) Markus Ringnér et al.   PLoS One

Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis

(2011) Shiaw-Wei Tyan et al.   PLoS One

Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts

(2010) Charlotta J Olsen et al.   BMC CANCER

Why not treat human cancer with interleukin-1 blockade?

(2010) Charles A. Dinarello   CANCER AND METASTASIS REVIEWS

Binding characteristics of the osteoarthritis-associated protein asporin

(2010) Ikuyo Kou et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies

(2010) Fiona M. Blows et al.   PLOS MEDICINE

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Smad3 Protein Levels Are Modulated by Ras Activity and during the Cell Cycle to Dictate Transforming Growth Factor-β Responses

(2009) Amanda C. Daly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The matricellular functions of small leucine-rich proteoglycans (SLRPs)

(2009) Rosetta Merline et al.   Journal of Cell Communication and Signaling

Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice

(2008) Shuiping Tu et al.   CANCER CELL

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

TGFβ in Cancer

(2008) Joan Massagué   CELL

Identification of new accessible tumor antigens in human colon cancer byex vivoprotein biotinylation and comparative mass spectrometry analysis

(2008) Paolo Conrotto et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs

(2008) Silvia Goldoni et al.   INTERNATIONAL JOURNAL OF CANCER