Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin

Published 2016 View Full Article

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Title
Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin
Authors
Keywords
high molecular weight products, fibrillation, covalent insulin dimer, SAXS, X-ray crystallography, ThT assay
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 105, Issue 4, Pages 1376-1386
Publisher
Elsevier BV
Online
2016-02-25
DOI
10.1016/j.xphs.2016.01.003

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