Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger

Ebola virus (EBOV) infection: Therapeutic strategies

(2015) Erik De Clercq   BIOCHEMICAL PHARMACOLOGY

Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

(2015) Yasuteru Sakurai et al.   SCIENCE

Ebola Virus and Severe Acute Respiratory Syndrome Coronavirus Display Late Cell Entry Kinetics: Evidence that Transport to NPC1+Endolysosomes Is a Rate-Defining Step

(2015) Rebecca M. Mingo et al.   JOURNAL OF VIROLOGY

Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin–Darby canine kidney cells

(2013) Steeve Boulant et al.   MOLECULAR BIOLOGY OF THE CELL

The Transmembrane Domain and Acidic Lipid Flip-Flop Regulates Voltage-Dependent Fusion Mediated by Class II and III Viral Proteins

(2013) Ruben M. Markosyan et al.   PLoS One

Viral Membrane Fusion and Nucleocapsid Delivery into the Cytoplasm are Distinct Events in Some Flaviviruses

(2013) Adel M. Nour et al.   PLoS Pathogens

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

Chinese hamster ovary cell lines selected for resistance to ebolavirus glycoprotein mediated infection are defective for NPC1 expression

(2012) Kathleen M. Haines et al.   VIROLOGY

Structural Basis for Differential Neutralization of Ebolaviruses

(2012) Shridhar Bale et al.   Viruses-Basel

Cathepsin Cleavage Potentiates the Ebola Virus Glycoprotein To Undergo a Subsequent Fusion-Relevant Conformational Change

(2011) M. Brecher et al.   JOURNAL OF VIROLOGY

Mutations in the Fusion Protein Cleavage Site of Avian Paramyxovirus Serotype 2 Increase Cleavability and Syncytium Formation but Do Not Increase Viral Virulence in Chickens

(2011) M. Subbiah et al.   JOURNAL OF VIROLOGY

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2

(2011) S. M. Gregory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: Stability and pH effects

(2011) Joseph S. Harrison et al.   PROTEIN SCIENCE

Differential requirements for clathrin endocytic pathway components in cellular entry by Ebola and Marburg glycoprotein pseudovirions

(2011) Suchita Bhattacharyya et al.   VIROLOGY

Single residues in the surface subunits of oncogenic sheep retrovirus envelopes distinguish receptor-mediated triggering for fusion at low pH and infection

(2011) Marceline Côté et al.   VIROLOGY

Ebola Virus Glycoprotein Needs an Additional Trigger, beyond Proteolytic Priming for Membrane Fusion

(2011) Shridhar Bale et al.   PLoS Neglected Tropical Diseases

Characterization of the receptor-binding domain of Ebola glycoprotein in viral entry

(2011) Jizhen Wang et al.   VIROLOGICA SINICA

Studies of the "Chain Reversal Regions" of the Avian Sarcoma/Leukosis Virus (ASLV) and Ebolavirus Fusion Proteins: Analogous Residues Are Important, and a His Residue Unique to EnvA Affects the pH Dependence of ASLV Entry

(2010) S. E. Delos et al.   JOURNAL OF VIROLOGY

Biochemical and Structural Characterization of Cathepsin L-Processed Ebola Virus Glycoprotein: Implications for Viral Entry and Immunogenicity

(2010) C. L. Hood et al.   JOURNAL OF VIROLOGY

Ebola haemorrhagic fever

(2010) Heinz Feldmann et al.   LANCET

HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes

(2009) Kosuke Miyauchi et al.   CELL

Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition

(2009) Osvaldo Martinez et al.   CELLULAR MICROBIOLOGY

The Primed Ebolavirus Glycoprotein (19-Kilodalton GP1,2): Sequence and Residues Critical for Host Cell Binding

(2009) D. Dube et al.   JOURNAL OF VIROLOGY

Enzootic Nasal Tumor Virus Envelope Requires a Very Acidic pH for Fusion Activation and Infection

(2008) M. Cote et al.   JOURNAL OF VIROLOGY

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

(2008) Jeffrey E. Lee et al.   NATURE