Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): a Systemic Infection

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The spatial landscape of lung pathology during COVID-19 progression

(2021) André F. Rendeiro et al.   NATURE

Epithelium-derived IL17A Promotes Cigarette Smoke-induced Inflammation and Mucus Hyperproduction

(2021) Mindan Wu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

(2020) Timothy P. Sheahan et al.   Nature Communications

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

(2020) Yvan Jamilloux et al.   AUTOIMMUNITY REVIEWS

Ellipticine blocks synergistic effects of IL-17A and TNF-α in epithelial cells and alleviates severe acute pancreatitis-associated acute lung injury

(2020) Xingli Li et al.   BIOCHEMICAL PHARMACOLOGY

Potential role of IL‐17 blocking agents in the treatment of severe COVID‐19?

(2020) Vedrana Bulat et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome

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Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

(2020) Bingwen Liu et al.   JOURNAL OF AUTOIMMUNITY

Systems pharmacology reveals the mechanism of activity of Ge-Gen-Qin-Lian decoction against LPS-induced acute lung injury: A novel strategy for exploring active components and effective mechanism of TCM formulae

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Immunopathology of Hyperinflammation in COVID-19

(2020) Joshua N. Gustine et al.   AMERICAN JOURNAL OF PATHOLOGY

Covid-19: Anti-TNF drug adalimumab to be trialled for patients in the community

(2020) Elisabeth Mahase   BMJ-British Medical Journal

The IL-17 Family of Cytokines in Health and Disease

(2019) Mandy J. McGeachy et al.   IMMUNITY

NETs promote ALI/ARDS inflammation by regulating alveolar macrophage polarization

(2019) Chao Song et al.   EXPERIMENTAL CELL RESEARCH

Asaronic Acid Attenuates Macrophage Activation toward M1 Phenotype through Inhibition of NF-κB Pathway and JAK-STAT Signaling in Glucose-Loaded Murine Macrophages

(2019) Hyeongjoo Oh et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Carvacrol suppresses LPS-induced pro-inflammatory activation in RAW 264.7 macrophages through ERK1/2 and NF-kB pathway

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Protective effect of Ganoderma atrum polysaccharides in acute lung injury rats and its metabolomics

(2019) Lu Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Neutrophil Elastase Inhibitors Suppress Oxidative Stress in Lung during Liver Transplantation

(2019) Weifeng Yao et al.   Oxidative Medicine and Cellular Longevity

ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway

(2019) Rensong Ye et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Enriched environment promotes post-stroke neurogenesis through NF-κB-mediated secretion of IL-17A from astrocytes

(2018) Yujing Zhang et al.   BRAIN RESEARCH

Cordycepin inhibits LPS-induced acute lung injury by inhibiting inflammation and oxidative stress

(2018) Jiaji Lei et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MicroRNA-27a alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis through modulating TLR4/MyD88/NF-κB pathway

(2018) MinJie Ju et al.   CELL CYCLE

PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

(2018) Lindsay J. Celada et al.   Science Translational Medicine

Syk Plays a Critical Role in the Expression and Activation of IRAK1 in LPS-Treated Macrophages

(2017) Jae Gwang Park et al.   MEDIATORS OF INFLAMMATION

Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury

(2016) Jiping Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis

(2016) Harini Raghu et al.   ANNALS OF THE RHEUMATIC DISEASES

Organizing pneumonia in mice and men

(2016) Nicole Izykowski et al.   Journal of Translational Medicine

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

BATMAN-TCM: a Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine

(2016) Zhongyang Liu et al.   Scientific Reports

Protective effects of polydatin on lipopolysaccharide-induced acute lung injury through TLR4-MyD88-NF-κB pathway

(2015) Qi Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome

(2015) John T. Li et al.   JOURNAL OF IMMUNOLOGY

Serum MMP-8 and TIMP-1 in Critically Ill Patients with Acute Respiratory Failure

(2014) Johanna Hästbacka et al.   ANESTHESIA AND ANALGESIA

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Acute pulmonary injury: high-resolution CT and histopathological spectrum

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CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin

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Mechanisms of Indirect Acute Lung Injury

(2011) Sean F. Monaghan et al.   ANNALS OF SURGERY

Kaempferol acts through mitogen-activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH