M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression
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Title
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression
Authors
Keywords
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Journal
ONCOGENE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-02-05
DOI
10.1038/s41388-022-02214-z
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- (2021) Mark Esposito et al. NATURE CELL BIOLOGY
- Potential role of m6A RNA methylation regulators in osteosarcoma and its clinical prognostic value
- (2021) Hua Liu et al. Journal of Orthopaedic Surgery and Research
- Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2
- (2020) Lei Zhou et al. BIOMEDICINE & PHARMACOTHERAPY
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- (2020) Huilin Huang et al. CANCER CELL
- N 6 ‐methyladenosine Reader Protein Ythdc2 Suppresses Liver Steatosis via Regulation of mRNA Stability of Lipogenic Genes
- (2020) Bing Zhou et al. HEPATOLOGY
- YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation
- (2020) Chuanzhao Zhang et al. ONCOGENE
- A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division
- (2020) Lovorka Stojic et al. Nature Communications
- Dysregulated m6A-Related Regulators Are Associated With Tumor Metastasis and Poor Prognosis in Osteosarcoma
- (2020) Jianhao Li et al. Frontiers in Oncology
- Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
- (2020) Rui Su et al. CANCER CELL
- Wnt signaling and Loxl2 promote aggressive osteosarcoma
- (2020) Kazuhiko Matsuoka et al. CELL RESEARCH
- LNC942 promoting METTL14-mediated m6A methylation in breast cancer cell proliferation and progression
- (2020) Tong Sun et al. ONCOGENE
- Osteosarcoma
- (2020) Bree R. Eaton et al. PEDIATRIC BLOOD & CANCER
- Bone Microenvironment and Osteosarcoma Metastasis
- (2020) Chaofei Yang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor
- (2020) Yiren Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LncRNA SNHG10 promotes the proliferation and invasion of osteosarcoma via Wnt/β-catenin signaling
- (2020) Shutao Zhu et al. Molecular Therapy-Nucleic Acids
- RNA N6-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m6A-GLUT1-mTORC1 Axis and Is a Therapeutic Target
- (2020) Huarong Chen et al. GASTROENTEROLOGY
- N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1α signalling axis
- (2019) Changshui Zhuang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
- (2019) Yue Huang et al. CANCER CELL
- Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1
- (2019) Shiming Peng et al. Science Translational Medicine
- Integrated analysis of transcriptome-wide m6A methylome of osteosarcoma stem cells enriched by chemotherapy
- (2019) Yongjie Wang et al. Epigenomics
- Changes in m6A RNA methylation contribute to heart failure progression by modulating translation
- (2019) Tea Berulava et al. EUROPEAN JOURNAL OF HEART FAILURE
- Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
- (2018) Huilin Huang et al. NATURE CELL BIOLOGY
- Understanding osteosarcomas
- (2018) Emily Simpson et al. JAAPA-Journal of the American Academy of Physician Assistants
- YTHDF2 suppresses cell proliferation and growth via destabilizing the EGFR mRNA in hepatocellular carcinoma
- (2018) Li Zhong et al. CANCER LETTERS
- Current and future therapeutic approaches for osteosarcoma
- (2017) Douglas J. Harrison et al. Expert Review of Anticancer Therapy
- Parkinson’s Disease: From Pathogenesis to Pharmacogenomics
- (2017) Ramón Cacabelos INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing
- (2016) Wen Xiao et al. MOLECULAR CELL
- Post-transcriptional gene regulation by mRNA modifications
- (2016) Boxuan Simen Zhao et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Messenger RNA modifications: Form, distribution, and function
- (2016) W. V. Gilbert et al. SCIENCE
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency
- (2015) Xiao Wang et al. CELL
- Aspirin Suppresses the Growth and Metastasis of Osteosarcoma through the NF- B Pathway
- (2015) D. Liao et al. CLINICAL CANCER RESEARCH
- Osteosarcoma treatment – Where do we stand? A state of the art review
- (2013) Anja Luetke et al. CANCER TREATMENT REVIEWS
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- Dact1 Is a Postsynaptic Protein Required for Dendrite, Spine, and Excitatory Synapse Development in the Mouse Forebrain
- (2010) N. D. Okerlund et al. JOURNAL OF NEUROSCIENCE
- Inactivation of the Fto gene protects from obesity
- (2009) Julia Fischer et al. NATURE
- Dapper1 Is a Nucleocytoplasmic Shuttling Protein That Negatively Modulates Wnt Signaling in the Nucleus
- (2008) Xia Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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