TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis

Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

(2020) David W. Sanders et al.   CELL

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling

(2019) Minhong Shen et al.   CANCER CELL

Wnt/Beta-Catenin Signaling Regulation and a Role for Biomolecular Condensates

(2019) Kristina N. Schaefer et al.   DEVELOPMENTAL CELL

Bone vascular niche E-selectin induces mesenchymal–epithelial transition and Wnt activation in cancer cells to promote bone metastasis

(2019) Mark Esposito et al.   NATURE CELL BIOLOGY

Organization and Function of Non-dynamic Biomolecular Condensates

(2018) Jeffrey B. Woodruff et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

(2018) Dan Bracha et al.   CELL

Heterozygous Pathogenic Variant inDACT1Causes an Autosomal-Dominant Syndrome with Features Overlapping Townes-Brocks Syndrome

(2017) Bryn D. Webb et al.   HUMAN MUTATION

P-Body Purification Reveals the Condensation of Repressed mRNA Regulons

(2017) Arnaud Hubstenberger et al.   MOLECULAR CELL

Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1

(2017) Xueqian Zhuang et al.   NATURE CELL BIOLOGY

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Biology of Bone Metastasis

(2017) Mark Esposito et al.   Cold Spring Harbor Perspectives in Medicine

Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT

(2016) Srinivas Malladi et al.   CELL

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Phase separation in biology; functional organization of a higher order

(2016) Diana M. Mitrea et al.   Cell Communication and Signaling

Systematic and general method for quantifying localization in microscopy images

(2016) Huanjie Sheng et al.   Biology Open

Myc-interacting zinc-finger protein 1 positively regulates Wnt signalling by protecting Dishevelled from Dapper1-mediated degradation

(2015) Yongsheng Huang et al.   BIOCHEMICAL JOURNAL

14-3-3ζ Turns TGF-β’s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2

(2015) Jia Xu et al.   CANCER CELL

The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases

(2015) Kasoha Mariz et al.   CLINICAL & EXPERIMENTAL METASTASIS

The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy

(2015) Benyu Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction

(2015) Mira I Pronobis et al.   eLife

Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation

(2014) Benyu Ma et al.   CELL RESEARCH

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling

(2013) Paloma Bragado et al.   NATURE CELL BIOLOGY

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Getting RNA and Protein in Phase

(2012) Stephanie C. Weber et al.   CELL

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

(2011) Saul Kivimäe et al.   BMC BIOCHEMISTRY

Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells

(2011) Nilay Sethi et al.   CANCER CELL

Protein Kinase A-mediated 14-3-3 Association Impedes Human Dapper1 to Promote Dishevelled Degradation

(2011) Hua Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Directed Protein Interaction Network for Investigating Intracellular Signal Transduction

(2011) A. Vinayagam et al.   Science Signaling

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

(2009) K. N. Retting et al.   DEVELOPMENT

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis

(2009) Manav Korpal et al.   NATURE MEDICINE

Optical imaging of cell mass and growth dynamics

(2008) Gabriel Popescu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

(2008) David Padua et al.   CELL

Dapper1 Is a Nucleocytoplasmic Shuttling Protein That Negatively Modulates Wnt Signaling in the Nucleus

(2008) Xia Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF-β1 and WISP-1/CCN-4 can regulate each other's activity to cooperatively control osteoblast function

(2008) Colette A. Inkson et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chromatin Immunoprecipitation on Microarray Analysis of Smad2/3 Binding Sites Reveals Roles of ETS1 and TFAP2A in Transforming Growth Factor   Signaling

(2008) D. Koinuma et al.   MOLECULAR AND CELLULAR BIOLOGY

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS