Integrated analysis of transcriptome-wide m6A methylome of osteosarcoma stem cells enriched by chemotherapy

Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice

(2019) Yiqin Wang et al.   Epigenomics

Primitive Cancer Cell States: A Target for Drug Screening?

(2019) Andrew C.A. Wan   TRENDS IN PHARMACOLOGICAL SCIENCES

Comprehensive analysis of differences of N6-methyladenosine RNA methylomes between high-fat-fed and normal mouse livers

(2019) Zupeng Luo et al.   Epigenomics

The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1

(2019) Wujun Miao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells

(2018) Xiao-tian Qi et al.   ACTA PHARMACOLOGICA SINICA

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification

(2018) Hengyou Weng et al.   Cell Stem Cell

Screening circular RNA related to chemotherapeutic resistance in osteosarcoma by RNA sequencing

(2018) Zhu Kun-Peng et al.   Epigenomics

m6A modulates haematopoietic stem and progenitor cell specification

(2017) Chunxia Zhang et al.   NATURE

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

(2017) Isaia Barbieri et al.   NATURE

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

(2017) Ly P Vu et al.   NATURE MEDICINE

Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens

(2017) Xuefeng Liu et al.   Nature Protocols

Germline and somatic genetics of osteosarcoma — connecting aetiology, biology and therapy

(2017) D. Matthew Gianferante et al.   Nature Reviews Endocrinology

MicroRNA-520b Suppresses Proliferation, Migration, and Invasion of Spinal Osteosarcoma Cells via Downregulation of Frizzled-8

(2017) Jin Wang et al.   ONCOLOGY RESEARCH

N 6 -methyladenosine is required for the hypoxic stabilization of specific mRNAs

(2017) Nate J. Fry et al.   RNA

m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

(2017) Qi Cui et al.   Cell Reports

SOAPnuke: a MapReduce acceleration-supported software for integrated quality control and preprocessing of high-throughput sequencing data

(2017) Yuxin Chen et al.   GigaScience

Chemotherapy induces stemness in osteosarcoma cells through activation of Wnt/β-catenin signaling

(2016) Sara R. Martins-Neves et al.   CANCER LETTERS

Advances in osteosarcoma stem cell research and opportunities for novel therapeutic targets

(2016) Guang-Ning Yan et al.   CANCER LETTERS

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing

(2016) Jin-zhao Ma et al.   HEPATOLOGY

Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial

(2016) Neyssa M Marina et al.   LANCET ONCOLOGY

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

(2016) Chuanzhao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting ABCB1 (MDR1) in multi-drug resistant osteosarcoma cells using the CRISPR-Cas9 system to reverse drug resistance

(2016) Tang Liu et al.   Oncotarget

Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling

(2016) Ling Yu et al.   Oncotarget

CXCR1 knockdown improves the sensitivity of osteosarcoma to cisplatin

(2015) Xiu-guo Han et al.   CANCER LETTERS

Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4

(2015) Sara R. Martins-Neves et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Osteosarcoma: Current Treatment and a Collaborative Pathway to Success

(2015) Michael S. Isakoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal

(2015) Suoyuan Li et al.   TUMOR BIOLOGY

Fate by RNA methylation: m6A steers stem cell pluripotency

(2015) Boxuan Zhao et al.   GENOME BIOLOGY

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

(2014) Mario L. Suvà et al.   CELL

Coleusin Factor, a Novel Anticancer Diterpenoid, Inhibits Osteosarcoma Growth by Inducing Bone Morphogenetic Protein-2-Dependent Differentiation

(2014) S. Geng et al.   MOLECULAR CANCER THERAPEUTICS

Conditionally Reprogrammed Normal and Transformed Mouse Mammary Epithelial Cells Display a Progenitor-Cell–Like Phenotype

(2014) Francisco R. Saenz et al.   PLoS One

Unique features of the m6A methylome in Arabidopsis thaliana

(2014) Guan-Zheng Luo et al.   Nature Communications

Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma

(2013) Yue Cheng et al.   BMC CELL BIOLOGY

diffReps: Detecting Differential Chromatin Modification Sites from ChIP-seq Data with Biological Replicates

(2013) Li Shen et al.   PLoS One

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Transforming Growth Factor β1 Signal is Crucial for Dedifferentiation of Cancer Cells to Cancer Stem Cells in Osteosarcoma

(2012) Haixia Zhang et al.   STEM CELLS

CD133 expression predicts lung metastasis and poor prognosis in osteosarcoma patients: A clinical and experimental study

(2012) AINA HE et al.   Experimental and Therapeutic Medicine

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model

(2011) Nino Rainusso et al.   CANCER BIOLOGY & THERAPY

BMP-2 inhibits the tumorigenicity of cancer stem cells in human osteosarcoma OS99-1 cell line

(2011) Lin Wang et al.   CANCER BIOLOGY & THERAPY

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

(2011) Derk ten Berge et al.   NATURE CELL BIOLOGY

Enrichment of osteosarcoma stem cells by chemotherapy

(2011) Qing-Lian Tang et al.   Chinese Journal of Cancer

CD117 and Stro-1 Identify Osteosarcoma Tumor-Initiating Cells Associated with Metastasis and Drug Resistance

(2010) Amit S. Adhikari et al.   CANCER RESEARCH

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Targeting the osteosarcoma cancer stem cell

(2010) Valerie A Siclari et al.   Journal of Orthopaedic Surgery and Research

DEGseq: an R package for identifying differentially expressed genes from RNA-seq data

(2009) Likun Wang et al.   BIOINFORMATICS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Detection and Characterization of CD133+ Cancer Stem Cells in Human Solid Tumours

(2008) Virginia Tirino et al.   PLoS One

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY