Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism

Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription

(2021) Lisa M. Ogawa et al.   MOLECULAR BIOLOGY OF THE CELL

nucleAIzer: A Parameter-free Deep Learning Framework for Nucleus Segmentation Using Image Style Transfer

(2020) Reka Hollandi et al.   Cell Systems

Regulation of ribosomal protein genes: An ordered anarchy

(2020) Cyrielle Petibon et al.   Wiley Interdisciplinary Reviews-RNA

Structure of the bacterial ribosome at 2 Å resolution

(2020) Zoe L Watson et al.   eLife

PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API

(2020) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

CRL4DCAF1/VprBP E3 ubiquitin ligase controls ribosome biogenesis, cell proliferation, and development

(2020) Xiao-Ran Han et al.   Science Advances

Uncovering the assembly pathway of human ribosomes and its emerging links to disease

(2019) Katherine E Bohnsack et al.   EMBO JOURNAL

Hallmarks of ribosomopathies

(2019) Kim R Kampen et al.   NUCLEIC ACIDS RESEARCH

Ribosomopathies: Old Concepts, New Controversies

(2019) Katherine I. Farley-Barnes et al.   TRENDS IN GENETICS

Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction

(2019) Alexey Rozov et al.   Nature Communications

Mechanism of ribosome stalling during translation of a poly(A) tail

(2019) Viswanathan Chandrasekaran et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The old and new biochemistry of polyamines

(2018) Dong-Hun Bae et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number

(2018) Katherine I. Farley-Barnes et al.   Cell Reports

Hypusine, a polyamine-derived amino acid critical for eukaryotic translation

(2018) Myung Hee Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ribosome biogenesis: An emerging druggable pathway for cancer therapeutics

(2018) Frédéric Catez et al.   BIOCHEMICAL PHARMACOLOGY

Roles of polyamines in translation

(2018) Thomas E. Dever et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ribosome assembly coming into focus

(2018) Sebastian Klinge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Comparison of preribosomal RNA processing pathways in yeast, plant and human cells - focus on coordinated action of endo- and exoribonucleases

(2017) Rafal Tomecki et al.   FEBS LETTERS

eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences

(2017) Vicent Pelechano et al.   NUCLEIC ACIDS RESEARCH

Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis

(2017) Byung-Sik Shin et al.   NUCLEIC ACIDS RESEARCH

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

A Puzzle of Life: Crafting Ribosomal Subunits

(2017) Dieter Kressler et al.   TRENDS IN BIOCHEMICAL SCIENCES

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

(2017) Philippe Cloutier et al.   Nature Communications

Advanced Cell Classifier: User-Friendly Machine-Learning-Based Software for Discovering Phenotypes in High-Content Imaging Data

(2017) Filippo Piccinini et al.   Cell Systems

Comparing CRISPR and RNAi-based screening technologies

(2016) Benjamin E Housden et al.   NATURE BIOTECHNOLOGY

The E3 Ubiquitin Ligase ARIH1 Protects against Genotoxic Stress by Initiating a 4EHP-Mediated mRNA Translation Arrest

(2015) Louise von Stechow et al.   MOLECULAR AND CELLULAR BIOLOGY

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

(2015) X. Li et al.   Molecular Systems Biology

CIDRE: an illumination-correction method for optical microscopy

(2015) Kevin Smith et al.   NATURE METHODS

High-resolution structure of the Escherichia coli ribosome

(2015) Jonas Noeske et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-resolution structure of the Escherichia coli ribosome

(2015) Jonas Noeske et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells

(2015) Lukas Badertscher et al.   Cell Reports

Antizyme (AZ) regulates intestinal cell growth independent of polyamines

(2014) Ramesh M. Ray et al.   AMINO ACIDS

The beta-isoform of the BRCA2 and CDKN1A(p21)-interacting protein (BCCIP) stabilizes nuclear RPL23/uL14

(2014) Emanuel Wyler et al.   FEBS LETTERS

Endogenous polyamine function—the RNA perspective

(2014) Helen L. Lightfoot et al.   NUCLEIC ACIDS RESEARCH

siPools: highly complex but accurately defined siRNA pools eliminate off-target effects

(2014) Michael Hannus et al.   NUCLEIC ACIDS RESEARCH

An overview of pre-ribosomal RNA processing in eukaryotes

(2014) Anthony K. Henras et al.   Wiley Interdisciplinary Reviews-RNA

A Conserved RhoGAP Limits M Phase Contractility and Coordinates with Microtubule Asters to Confine RhoA during Cytokinesis

(2013) Esther Zanin et al.   DEVELOPMENTAL CELL

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

The Complexity of Human Ribosome Biogenesis Revealed by Systematic Nucleolar Screening of Pre-rRNA Processing Factors

(2013) Lionel Tafforeau et al.   MOLECULAR CELL

eIF5A Promotes Translation of Polyproline Motifs

(2013) Erik Gutierrez et al.   MOLECULAR CELL

5S Ribosomal RNA Is an Essential Component of a Nascent Ribosomal Precursor Complex that Regulates the Hdm2-p53 Checkpoint

(2013) Giulio Donati et al.   Cell Reports

The 5S RNP Couples p53 Homeostasis to Ribosome Biogenesis and Nucleolar Stress

(2013) Katherine E. Sloan et al.   Cell Reports

Expression Profiling and Biochemical Analysis Suggest Stress Response as a Potential Mechanism Inhibiting Proliferation of Polyamine-depleted Cells

(2012) Guy Landau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of High Accuracy, Quantitative Proteomics Data in the MaxQB Database

(2012) Christoph Schaab et al.   MOLECULAR & CELLULAR PROTEOMICS

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

Identification of DHX33 as a Mediator of rRNA Synthesis and Cell Growth

(2011) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Deep proteome and transcriptome mapping of a human cancer cell line

(2011) N. Nagaraj et al.   Molecular Systems Biology

Trithorax group proteins: switching genes on and keeping them active

(2011) Bernd Schuettengruber et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RRP1B Targets PP1 to Mammalian Cell Nucleoli and Is Associated with Pre-60S Ribosomal Subunits

(2010) Delphine Chamousset et al.   MOLECULAR BIOLOGY OF THE CELL

Genome-wide analysis of YY2 versus YY1 target genes

(2010) Li Chen et al.   NUCLEIC ACIDS RESEARCH

Tandem affinity purification combined with inducible shRNA expression as a tool to study the maturation of macromolecular assemblies

(2010) E. Wyler et al.   RNA

A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

(2010) Thomas Wild et al.   PLOS BIOLOGY

Driving ribosome assembly

(2009) Dieter Kressler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2

(2009) Ivo Zemp et al.   JOURNAL OF CELL BIOLOGY

Proteasomal ATPases are associated with rDNA: The ubiquitin proteasome system plays a direct role in RNA polymerase I transcription

(2008) Károly Fátyol et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

(2008) Séverine Boulon et al.   JOURNAL OF CELL BIOLOGY

Molecular Regulation of H3K4 Trimethylation by Wdr82, a Component of Human Set1/COMPASS

(2008) M. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

NOPdb: Nucleolar Proteome Database--2008 update

(2008) Y. Ahmad et al.   NUCLEIC ACIDS RESEARCH