Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin

Interaction of 7SK with the Smn complex modulates snRNP production

(2021) Changhe Ji et al.   Nature Communications

Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS

(2019) Lauren M. Gittings et al.   Acta Neuropathologica Communications

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

(2019) Joy Mitra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HNRNPR Variants that Impair Homeobox Gene Expression Drive Developmental Disorders in Humans

(2019) Floor A. Duijkers et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Emerging Perspectives on DNA double-strand breaks in Neurodegenerative Diseases

(2019) Ling-Shuang Zhu et al.   Current Neuropharmacology

HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis

(2019) Er-Bao Chen et al.   Aging-US

Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy

(2018) Annapoorna Kannan et al.   NUCLEIC ACIDS RESEARCH

hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

(2018) Michael Briese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

(2018) Marcel Naumann et al.   Nature Communications

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors

(2018) Elizaveta Alemasova et al.   Oncotarget

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins

(2018) Binkai Chi et al.   Scientific Reports

Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis

(2018) Haibo Wang et al.   Nature Communications

SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage

(2017) Mohini Jangi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS

(2016) Marisa Kamelgarn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Y-box-binding protein 1 as a non-canonical factor of base excision repair

(2016) Elizaveta E. Alemasova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The hnRNP family: insights into their role in health and disease

(2016) Thomas Geuens et al.   HUMAN GENETICS

HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins

(2016) Adi Reches et al.   JOURNAL OF IMMUNOLOGY

Y-box binding protein 1 (YB-1) promotes detection of DNA bulky lesions by XPC-HR23B factor

(2015) E. E. Fomina et al.   BIOCHEMISTRY-MOSCOW

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease

(2015) Paola Briata et al.   Wiley Interdisciplinary Reviews-RNA

Deep Proteomic Evaluation of Primary and Cell Line Motoneuron Disease Models Delineates Major Differences in Neuronal Characteristics

(2014) Daniel Hornburg et al.   MOLECULAR & CELLULAR PROTEOMICS

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons

(2014) Benjamin Dombert et al.   PLoS One

Self-assembled FUS binds active chromatin and regulates gene transcription

(2014) Liuqing Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA damage: RNA-binding proteins protect from near and far

(2014) Martin Dutertre et al.   TRENDS IN BIOCHEMICAL SCIENCES

OpenComet: An automated tool for comet assay image analysis

(2014) Benjamin M. Gyori et al.   Redox Biology

The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress

(2013) Ekaterina R Kim et al.   CELL CYCLE

Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR)

(2013) O. Solomon et al.   RNA

YB-1 protein: functions and regulation

(2013) Dmitry N. Lyabin et al.   Wiley Interdisciplinary Reviews-RNA

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Primer3—new capabilities and interfaces

(2012) Andreas Untergasser et al.   NUCLEIC ACIDS RESEARCH

Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins

(2012) Stephanie C. Huelga et al.   Cell Reports

Quantitative, High-Resolution Proteomics for Data-Driven Systems Biology

(2011) Jürgen Cox et al.   Annual Review of Biochemistry

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Functional diversity of the hnRNPs: past, present and perspectives

(2010) Siew Ping Han et al.   BIOCHEMICAL JOURNAL

The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal β-actin mRNA translocation in spinal motor neurons

(2010) Michael Glinka et al.   HUMAN MOLECULAR GENETICS

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

RNA-binding specificity of Y-box protein 1

(2010) Jinjiang Dong et al.   RNA Biology

Heterogeneous Nuclear Ribonucleoprotein R Enhances Transcription from the Naturally Configured c-fosPromoterin Vitro

(2009) Aya Fukuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic Dissection of Cell Type-Specific H2AX-Interacting Protein Complex Associated with Hepatocellular Carcinoma

(2009) Xiaoli Yang et al.   JOURNAL OF PROTEOME RESEARCH

Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery

(2009) Brian D. Freibaum et al.   JOURNAL OF PROTEOME RESEARCH

Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos

(2009) Stefan Wiese et al.   Nature Protocols

A new non-disruptive strategy to target calcium indicator dyes to the endoplasmic reticulum

(2008) Markus Rehberg et al.   CELL CALCIUM

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY