webTWAS: a resource for disease candidate susceptibility genes identified by transcriptome-wide association study

Multi-trait transcriptome-wide association studies with probabilistic Mendelian randomization

(2021) Lu Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies

(2021) Arjun Bhattacharya et al.   PLoS Genetics

Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer’s disease

(2021) Nana Liu et al.   PLoS Genetics

Power analysis of transcriptome-wide association study: Implications for practical protocol choice

(2021) Chen Cao et al.   PLoS Genetics

Ethnically biased microsatellites contribute to differential gene expression and glutathione metabolism in Africans and Europeans

(2021) Nick Kinney et al.   PLoS One

Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults

(2021) Binglan Li et al.   PLoS Genetics

Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer’s dementia

(2021) Shizhen Tang et al.   PLoS Genetics

Population-specific genetic and expression differentiation in Europeans

(2020) Xueyuan Jiang et al.   Genome Biology and Evolution

Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk

(2020) Andrew E. Jaffe et al.   NATURE NEUROSCIENCE

Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics

(2020) Justin M. Luningham et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis

(2020) Dan Zhou et al.   NATURE GENETICS

A tissue-specific collaborative mixed model for jointly analyzing multiple tissues in transcriptome-wide association studies

(2020) Xingjie Shi et al.   NUCLEIC ACIDS RESEARCH

kTWAS: integrating kernel machine with transcriptome-wide association studies improves statistical power and reveals novel genes

(2020) Chen Cao et al.   BRIEFINGS IN BIOINFORMATICS

Probabilistic fine-mapping of transcriptome-wide association studies

(2019) Nicholas Mancuso et al.   NATURE GENETICS

Opportunities and challenges for transcriptome-wide association studies

(2019) Michael Wainberg et al.   NATURE GENETICS

Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration

(2019) Rinki Ratnapriya et al.   NATURE GENETICS

A statistical framework for cross-tissue transcriptome-wide association analysis

(2019) Yiming Hu et al.   NATURE GENETICS

deTS: tissue-specific enrichment analysis to decode tissue specificity

(2019) Guangsheng Pei et al.   BIOINFORMATICS

A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants

(2019) Alexander Gusev et al.   NATURE GENETICS

PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations

(2019) Mihir A Kamat et al.   BIOINFORMATICS

TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits

(2019) Sini Nagpal et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GWAS Atlas: a curated resource of genome-wide variant-trait associations in plants and animals

(2019) Dongmei Tian et al.   NUCLEIC ACIDS RESEARCH

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

(2018) Lang Wu et al.   NATURE GENETICS

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

(2018) Alexander Gusev et al.   NATURE GENETICS

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

(2018) Sébastien Thériault et al.   Nature Communications

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

(2018) Alvaro N. Barbeira et al.   Nature Communications

An atlas of genetic associations in UK Biobank

(2018) Oriol Canela-Xandri et al.   NATURE GENETICS

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

(2016) Jie Zheng et al.   BIOINFORMATICS

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics

(2016) David Lamparter et al.   PLoS Computational Biology

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

A gene-based association method for mapping traits using reference transcriptome data

(2015) Eric R Gamazon et al.   NATURE GENETICS

GWASdb v2: an update database for human genetic variants identified by genome-wide association studies

(2015) Mulin Jun Li et al.   NUCLEIC ACIDS RESEARCH

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

GRASP v2.0: an update on the Genome-Wide Repository of Associations between SNPs and phenotypes

(2014) John D. Eicher et al.   NUCLEIC ACIDS RESEARCH

NCBI’s Database of Genotypes and Phenotypes: dbGaP

(2013) Kimberly A. Tryka et al.   NUCLEIC ACIDS RESEARCH