Quantitative detection of grey and white matter amyloid pathology using a combination of K114 and CRANAD-3 fluorescence

Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study

(2021) Johannes Attems et al.   ACTA NEUROPATHOLOGICA

Complex Photophysical Properties of K114 Make for a Versatile Fluorescent Probe for Amyloid Detection

(2021) Anastasiia A. Stepanchuk et al.   ACS Chemical Neuroscience

Investigation of pathology, expression and proteomic profiles in human TREM2 variant postmortem brains with and without Alzheimer’s disease

(2020) Christina E. Toomey et al.   BRAIN PATHOLOGY

Aβ and tau prion-like activities decline with longevity in the Alzheimer’s disease human brain

(2019) Atsushi Aoyagi et al.   Science Translational Medicine

Alzheimer's Disease Including Focal Presentations

(2019) Nicolas Villain et al.   SEMINARS IN NEUROLOGY

Environment-Sensitive Near-Infrared Probe for Fluorescent Discrimination of Aβ and Tau Fibrils in AD Brain

(2019) Kaixiang Zhou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Interrogating Amyloid Aggregates using Fluorescent Probes

(2019) Amir Aliyan et al.   CHEMICAL REVIEWS

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue

(2019) Marius Kollmer et al.   Nature Communications

Cerebral amyloid angiopathy and Alzheimer disease — one peptide, two pathways

(2019) Steven M. Greenberg et al.   Nature Reviews Neurology

Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores

(2018) Peter Verwilst et al.   CHEMICAL SOCIETY REVIEWS

Detection and Imaging of Aβ1-42 and Tau Fibrils by Redesigned Fluorescent X-34 Analogues

(2018) Jun Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

(2018) Erika N. Cline et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid fibril polymorphism: a challenge for molecular imaging and therapy

(2018) M. Fändrich et al.   JOURNAL OF INTERNAL MEDICINE

Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease

(2018) Carlo Condello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases

(2018) Mathias Jucker et al.   NATURE NEUROSCIENCE

Axonal and myelinic pathology in 5xFAD Alzheimer’s mouse spinal cord

(2017) Tak-Ho Chu et al.   PLoS One

Updated TDP-43 in Alzheimer’s disease staging scheme

(2016) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease

(2016) Mark Cohen et al.   Prion

The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

(2016) Urmi Sengupta et al.   EBioMedicine

Rapidly progressive Alzheimer’s disease features distinct structures of amyloid-β

(2015) Mark L. Cohen et al.   BRAIN

Definition of a Molecular Pathway Mediating  -Synuclein Neurotoxicity

(2015) J. Burre et al.   JOURNAL OF NEUROSCIENCE

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

(2015) Xueli Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice

(2015) Jack Brelstaff et al.   Frontiers in Neuroscience

Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target

(2014) Brandon B. Holmes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands

(2014) Karin Magnusson et al.   Prion

Serial propagation of distinct strains of A  prions from Alzheimer's disease patients

(2014) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

(2013) Xueli Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome

(2013) Benjamin Lam et al.   Alzheimers Research & Therapy

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls

(2012) Thomas J. Esparza et al.   ANNALS OF NEUROLOGY

Insight into Amyloid Structure Using Chemical Probes

(2011) Ashley A. Reinke et al.   Chemical Biology & Drug Design

Structural Insights into Functional and Pathological Amyloid

(2011) Frank Shewmaker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble A  Seeds Are Potent Inducers of Cerebral  -Amyloid Deposition

(2011) F. Langer et al.   JOURNAL OF NEUROSCIENCE

Spectral Unmixing Imaging of Wavelength-Responsive Fluorescent Probes: An Application for the Real-Time Report of Amyloid Beta Species in Alzheimer’s Disease

(2011) Chongzhao Ran et al.   MOLECULAR IMAGING AND BIOLOGY

Discrepancies between descriptions and illustrations of colours in Congo red-stained amyloid, and explanation of discrepant colours

(2010) Alexander J. Howie et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

A Fluorescent Pentameric Thiophene Derivative Detects in Vitro-Formed Prefibrillar Protein Aggregates

(2010) Per Hammarström et al.   BIOCHEMISTRY

Molecular mechanism of Thioflavin-T binding to amyloid fibrils

(2010) Matthew Biancalana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Novel Pentameric Thiophene Derivatives forin Vitroandin VivoOptical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses

(2009) Andreas Åslund et al.   ACS Chemical Biology

Oligomers of β-amyloid are sequestered into and seed new plaques in the brains of an AD mouse model

(2009) Renee C. Gaspar et al.   EXPERIMENTAL NEUROLOGY

Beta-Amyloid Deposition and the Aging Brain

(2009) Karen M. Rodrigue et al.   NEUROPSYCHOLOGY REVIEW

Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology

(2008) A. A. Gouw et al.   BRAIN

Optical properties of amyloid stained by Congo red: History and mechanisms

(2008) Alexander J. Howie et al.   MICRON

White matter pathology isolates the hippocampal formation in Alzheimer's disease

(2008) D.H. Salat et al.   NEUROBIOLOGY OF AGING