CORM-2 inhibits TXNIP/NLRP3 inflammasome pathway in LPS-induced acute lung injury

Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages

(2015) Sung-Soo Jung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Carbon monoxide decreases interleukin-1β levels in the lung through the induction of pyrin

(2015) Seul-Ki Kim et al.   Cellular & Molecular Immunology

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages

(2015) Thomas Gicquel et al.   FASEB JOURNAL

Role of the nucleotide-binding domain-like receptor protein 3 inflammasome in acute kidney injury

(2015) Yanhui Cao et al.   FEBS Journal

Nrf2 is essential for the anti-inflammatory effect of carbon monoxide in LPS-induced inflammation

(2015) SiYuan Qin et al.   INFLAMMATION RESEARCH

TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury

(2014) Yi Liu et al.   BASIC RESEARCH IN CARDIOLOGY

Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1

(2014) Yun-peng Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Critical Role for the NLRP3 Inflammasome during Acute Lung Injury

(2014) J. J. Grailer et al.   JOURNAL OF IMMUNOLOGY

NLRP3 deletion protects from hyperoxia-induced acute lung injury

(2013) Jutaro Fukumoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury

(2013) Naoko Kamo et al.   HEPATOLOGY

ATP-P2X4 signaling mediates NLRP3 inflammasome activation: A novel pathway of diabetic nephropathy

(2013) Kehong Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Carbon monoxide–based therapy ameliorates acute pancreatitis via TLR4 inhibition

(2013) Jing Xue et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of NLRP3 Inflammasome in Alveolar Macrophages Contributes to Mechanical Stretch-Induced Lung Inflammation and Injury

(2013) J. Wu et al.   JOURNAL OF IMMUNOLOGY

The inflammasome in lung diseases

(2012) Gimena dos Santos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

(2012) Tamás Dolinay et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ventilator-induced Lung Injury Is Mediated by the NLRP3 Inflammasome

(2012) Maria T. Kuipers et al.   ANESTHESIOLOGY

Heme Oxygenase-1/Carbon Monoxide: Novel Therapeutic Strategies in Critical Care Medicine

(2012) Stefan W. Ryter et al.   CURRENT DRUG TARGETS

Carbon Monoxide in Acute Lung Injury

(2012) Simone Faller et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Interleukin-18 levels reflect the long-term prognosis of acute lung injury and acute respiratory distress syndrome

(2012) Hideyuki Makabe et al.   Journal of Anesthesia

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

NALP-3 inflammasome silencing attenuates ceramide-induced transepithelial permeability

(2011) Narasaiah Kolliputi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Unknown

(2011) Jochen Grommes et al.   MOLECULAR MEDICINE

The carbon monoxide donor, CORM-2, is an antagonist of ATP-gated, human P2X4 receptors

(2011) William James Wilkinson et al.   Purinergic Signalling

Beyond Mortality

(2010) Roger G. Spragg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interleukin-1β induces ICAM-1 expression enhancing leukocyte adhesion in human rheumatoid arthritis synovial fibroblasts: Involvement of ERK, JNK, AP-1, and NF-κB

(2010) Chuen-Mao Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Carbon Monoxide From CORM-2 Reduces HMGB1 Release Through Regulation of IFN-β/JAK2/STAT-1/INOS/NO Signaling But Not COX-2 in TLR-Activated Macrophages

(2010) Konstantin Tsoyi et al.   SHOCK

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

Heme-Oxygenase-1 Induction and Carbon Monoxide-Releasing Molecule Inhibit Lipopolysaccharide (LPS)-Induced High-Mobility Group Box 1 Release in Vitro and Improve Survival of Mice in LPS- and Cecal Ligation and Puncture-Induced Sepsis Model in Vivo

(2009) K. Tsoyi et al.   MOLECULAR PHARMACOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY