Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

Modulation of Inflammasome Pathways by Bacterial and Viral Pathogens

(2011) M. Lamkanfi et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Clinical Characteristics and Outcomes of Sepsis-Related vs Non-Sepsis-Related ARDS

(2010) Chau-Chyun Sheu et al.   CHEST

The Inflammasome Mediates Hyperoxia-Induced Alveolar Cell Permeability

(2010) N. Kolliputi et al.   JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

A Functional Polymorphism inIL-18Is Associated with Severity of Bronchial Asthma

(2009) Michishige Harada et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of Proinflammatory Cytokines IL-18 and IL-1β in Bleomycin-Induced Lung Injury in Humans and Mice

(2009) Tomoaki Hoshino et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Clara Cell Protein (CC16), a Marker of Lung Epithelial Injury, Is Decreased in Plasma and Pulmonary Edema Fluid From Patients With Acute Lung Injury

(2009) Jonathan A. Kropski et al.   CHEST

Prognostic and Pathogenetic Value of Combining Clinical and Biochemical Indices in Patients With Acute Lung Injury

(2009) Lorraine B. Ware et al.   CHEST

Biomarkers in acute lung injury: Are we making progress?*

(2009) Sushma K. Cribbs et al.   CRITICAL CARE MEDICINE

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

(2009) Alexander U. Lüthi et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Discovery of the gene signature for acute lung injury in patients with sepsis

(2009) Judie A. Howrylak et al.   PHYSIOLOGICAL GENOMICS

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasome mRNA Expression in Human Monocytes during Early Septic Shock

(2008) Ruairi J. Fahy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mortality Rates for Patients With Acute Lung Injury/ARDS Have Decreased Over Time

(2008) Massimo Zambon et al.   CHEST

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Mitogen-Activated Protein Kinases Regulate Susceptibility to Ventilator-Induced Lung Injury

(2008) Tamás Dolinay et al.   PLoS One