Silica nanoparticles enhance autophagic activity, disturb endothelial cell homeostasis and impair angiogenesis

United States Government Accountability Office Report on Nanotechnology: Nanomaterials Are Widely Used in Commerce, but EPA Faces Challenges in Regulating Risk

(2014)   INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Silica nanoparticles induce autophagy and autophagic cell death in HepG2 cells triggered by reactive oxygen species

(2014) Yongbo Yu et al.   JOURNAL OF HAZARDOUS MATERIALS

Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model

(2013) Junchao Duan et al.   BIOMATERIALS

New Insights Into Pollution and the Cardiovascular System

(2013) Diane R. Gold et al.   CIRCULATION

Intrinsic Structural Disorder in Cytoskeletal Proteins

(2013) Mainak Guharoy et al.   Cytoskeleton

Global life cycle releases of engineered nanomaterials

(2013) Arturo A. Keller et al.   JOURNAL OF NANOPARTICLE RESEARCH

Nanoparticle-induced photocatalytic head and neck squamous cell carcinoma cell death is associated with autophagy

(2013) Stephan Hackenberg et al.   Nanomedicine

Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

(2013) Yang Yu et al.   PLoS One

Toxic Effect of Silica Nanoparticles on Endothelial Cells through DNA Damage Response via Chk1-Dependent G2/M Checkpoint

(2013) Junchao Duan et al.   PLoS One

Toxic Effects of Silica Nanoparticles on Zebrafish Embryos and Larvae

(2013) Junchao Duan et al.   PLoS One

Cerium Dioxide Nanoparticles Induce Apoptosis and Autophagy in Human Peripheral Blood Monocytes

(2012) Salik Hussain et al.   ACS Nano

Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension

(2012) Ru-Jeng Teng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mitochondria in Vascular Health and Disease

(2012) Peter Dromparis et al.   Annual Review of Physiology

Monocyte chemotactic protein-induced protein (MCPIP) promotes inflammatory angiogenesis via sequential induction of oxidative stress, endoplasmic reticulum stress and autophagy

(2012) Arpita Roy et al.   CELLULAR SIGNALLING

Mesoporous silica nanoparticles in biomedical applications

(2012) Zongxi Li et al.   CHEMICAL SOCIETY REVIEWS

Molecules and their functions in autophagy

(2012) Jong-Ok Pyo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Oxidative stress mediates chemerin-induced autophagy in endothelial cells

(2012) Weili Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Multifunctional Mesoporous Silica Nanocomposite Nanoparticles for Theranostic Applications

(2011) Ji Eun Lee et al.   ACCOUNTS OF CHEMICAL RESEARCH

Role of autophagy in angiogenesis in aortic endothelial cells

(2011) Jianhai Du et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autophagy and the cytoskeleton

(2011) Serge Mostowy et al.   Autophagy

Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles

(2011) Mohd Imran Khan et al.   BIOMATERIALS

Saharan dust contribution to PM10, PM2.5 and PM1 in urban and suburban areas of Rome: a comparison between single-particle SEM-EDS analysis and whole-sample PIXE analysis

(2011) Luca Matassoni et al.   JOURNAL OF ENVIRONMENTAL MONITORING

Bevacizumab attenuates major signaling cascades and eIF4E translation initiation factor in multiple myeloma cells

(2011) Oshrat Attar-Schneider et al.   LABORATORY INVESTIGATION

Alpha-alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response

(2011) Haiyan Li et al.   Nature Nanotechnology

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Cytotoxicity and mitochondrial damage caused by silica nanoparticles

(2011) Lei Sun et al.   TOXICOLOGY IN VITRO

A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt–TSC2-mTOR signaling

(2011) H-L Liu et al.   Cell Death & Disease

FITC and Ru(phen)32+ co-doped silica particles as visualized ratiometric pH indicator

(2011) Jianquan Xu et al.   Nanoscale Research Letters

A review of the characteristics of nanoparticles in the urban atmosphere and the prospects for developing regulatory controls

(2010) Prashant Kumar et al.   ATMOSPHERIC ENVIRONMENT

Particulate Matter Air Pollution and Cardiovascular Disease

(2010) Robert D. Brook et al.   CIRCULATION

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness

(2010) Maciej Kotecki et al.   MICROVASCULAR RESEARCH

Endothelial cell-selective adhesion molecule modulates atherosclerosis through plaque angiogenesis and monocyte–endothelial interaction

(2010) Michihiko Inoue et al.   MICROVASCULAR RESEARCH

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function

(2009) Xinglu Huang et al.   BIOMATERIALS

Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats

(2008) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Nanoquartz in Late Permian C1 coal and the high incidence of female lung cancer in the Pearl River Origin area: a retrospective cohort study

(2008) Linwei Tian et al.   BMC PUBLIC HEALTH

Autophagy as an ultrastructural marker of heavy metal toxicity in human cord blood hematopoietic stem cells

(2008) Mario Di Gioacchino et al.   SCIENCE OF THE TOTAL ENVIRONMENT