Hypoxia-Inducible Factor-1α and Autoimmune Lupus, Arthritis

HMGB1 induces angiogenesis in rheumatoid arthritis via HIF-1α activation

(2015) So Youn Park et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Andrographolide inhibits the migration, invasion and matrix metalloproteinase expression of rheumatoid arthritis fibroblast-like synoviocytes via inhibition of HIF-1α signaling

(2015) Guo-feng Li et al.   LIFE SCIENCES

Hypoxia Inducible Factor-1 Alpha Promotes Mesangial Cell Proliferation in Lupus Nephritis

(2014) Wei Deng et al.   AMERICAN JOURNAL OF NEPHROLOGY

Short-Term Hypoxia Enhances the Migratory Capability of Dendritic Cell Through HIF-1α and PI3K/Akt Pathway

(2014) Irene Filippi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hypoxia and Hypoxia-Inducible Factor-1  Modulate Lipopolysaccharide-Induced Dendritic Cell Activation and Function

(2014) J. Jantsch et al.   JOURNAL OF IMMUNOLOGY

Effect of HIF1α on Foxp3 expression in CD4+CD25−T lymphocytes

(2014) Jianguo Wu et al.   MICROBIOLOGY AND IMMUNOLOGY

Hypoxia and hypoxia-inducible factor-1α provoke toll-like receptor signalling-induced inflammation in rheumatoid arthritis

(2013) Fanlei Hu et al.   ANNALS OF THE RHEUMATIC DISEASES

Lack of association between the polymorphisms of hypoxia-inducible factor 1A (HIF1A) gene and SLE susceptibility in a Chinese population

(2013) Chen-Chen Feng et al.   IMMUNOGENETICS

Hypoxia-Inducible Factor-1α and Interleukin 33 Form a Regulatory Circuit to Perpetuate the Inflammation in Rheumatoid Arthritis

(2013) Fanlei Hu et al.   PLoS One

Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration

(2012) Theresa Köhler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PI3 kinase/Akt/HIF-1α pathway is associated with hypoxia-induced epithelial–mesenchymal transition in fibroblast-like synoviocytes of rheumatoid arthritis

(2012) Guo-Qing Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α pathway

(2012) Guoqing Li et al.   MOLECULAR IMMUNOLOGY

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

(2012) E. T. Clambey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urinary Hypoxia-Inducible Factor-1alpha Levels Are Associated with Histologic Chronicity Changes and Renal Function in Patients with Lupus Nephritis

(2012) Chunyang Ma et al.   YONSEI MEDICAL JOURNAL

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hypoxia differentially affects IL-1 -stimulated MMP-1 and MMP-13 expression of fibroblast-like synoviocytes in an HIF-1 -dependent manner

(2011) Y.-A. Lee et al.   RHEUMATOLOGY

Expression and regulation of HIF-1alpha in macrophages under inflammatory conditions; significant reduction of VEGF by CaMKII inhibitor

(2010) Johanna Westra et al.   BMC MUSCULOSKELETAL DISORDERS

Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4

(2010) Helen J. Knowles et al.   FASEB JOURNAL

Human inflammatory synovial fibroblasts induce enhanced myeloid cell recruitment and angiogenesis through a hypoxia-inducible transcription factor 1α/vascular endothelial growth factor-mediated pathway in immunodeficient mice

(2009) Manuel J. del Rey et al.   ARTHRITIS AND RHEUMATISM

HIF-1 in the inflammatory microenvironment

(2009) Nathalie Dehne et al.   EXPERIMENTAL CELL RESEARCH

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis

(2009) Helen J Knowles et al.   JOURNAL OF PATHOLOGY

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

(2009) Catherine E Forristal et al.   REPRODUCTION

Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α

(2008) Jeremy Ben-Shoshan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of hypoxia-inducible factor-1  in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes

(2008) J. K. Ahn et al.   RHEUMATOLOGY