Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4

A compact VEGF signature associated with distant metastases and poor outcomes

(2009) Zhiyuan Hu et al.   BMC Medicine

Genomic Profiling of Chondrosarcoma: Chromosomal Patterns in Central and Peripheral Tumors

(2009) K. H. Hallor et al.   CLINICAL CANCER RESEARCH

Hypoxia-inducible factors 1α and 2α exert both distinct and overlapping functions in long bone development

(2009) Stacy H. Shomento et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice

(2009) Xing Shen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis

(2009) Helen J Knowles et al.   JOURNAL OF PATHOLOGY

Suppression of the Raf/MEK/ERK Signaling Cascade and Inhibition of Angiogenesis by the Carboxyl Terminus of Angiopoietin-Like Protein 4

(2008) Ying-Hua Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis

(2008) Hironori Adachi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of soluble cobalt and cobalt incorporated into calcium phosphate layers on osteoclast differentiation and activation

(2008) Somying Patntirapong et al.   BIOMATERIALS

The specific contribution of hypoxia-inducible factor-2α to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors

(2008) Christina Warnecke et al.   EXPERIMENTAL CELL RESEARCH

Interaction of the coiled-coil domain with glycosaminoglycans protects angiopoietin-like 4 from proteolysis and regulates its antiangiogenic activity

(2008) Clémence Chomel et al.   FASEB JOURNAL

Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: Role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation

(2008) Minako Murata et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte–osteoclast differentiation via induction of VEGF

(2008) HJ Knowles et al.   JOURNAL OF PATHOLOGY

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia

(2008) Aline Bozec et al.   NATURE

Activation of the hypoxia-inducible factor-1  pathway accelerates bone regeneration

(2008) C. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism

(2008) Tai Hato et al.   TRENDS IN CARDIOVASCULAR MEDICINE