Label-free cell assays to determine compound uptake or drug action using MALDI-TOF mass spectrometry

Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs

(2020) Melissa S. Unger et al.   ANALYTICAL CHEMISTRY

Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI

(2020) Qiuqin Zhou et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

MALDI-TOF Mass Spectrometry-Based High-Throughput Screening for Inhibitors of the Cytosolic DNA Sensor cGAS

(2019) Roman P. Simon et al.   SLAS Discovery

Detection of Ovarian Cancer Using Samples Sourced from the Vaginal Microenvironment

(2019) Melissa M. Galey et al.   JOURNAL OF PROTEOME RESEARCH

Testing therapeutics in cell-based assays: Factors that influence the apparent potency of drugs

(2018) Elena Postnikova et al.   PLoS One

Design of experiment in assessing robustness and for qualification of a cell-based potency assay

(2018) Robert Wilson   Bioanalysis

A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer’s disease drug target β-secretase

(2018) Markéta Machálková et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Automated analysis of lipid drug-response markers by combined fast and high-resolution whole cell MALDI mass spectrometry biotyping

(2018) David Weigt et al.   Scientific Reports

Advanced MALDI mass spectrometry imaging in pharmaceutical research and drug development

(2018) Sandra Schulz et al.   CURRENT OPINION IN BIOTECHNOLOGY

Time-Resolved Fluorescence Resonance Energy Transfer [TR-FRET] Assays for Biochemical Processes

(2016) Ekin Ergin et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Cell-Based Assay Design for High-Content Screening of Drug Candidates

(2016) Gregory Nierode et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Quantitative analysis of endogenous compounds

(2016) Rhishikesh Thakare et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The quest for improved reproducibility in MALDI mass spectrometry

(2016) Matthew B. O'Rourke et al.   MASS SPECTROMETRY REVIEWS

High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue

(2016) Alice Ly et al.   Nature Protocols

Screening out irrelevant cell-based models of disease

(2016) Peter Horvath et al.   NATURE REVIEWS DRUG DISCOVERY

Label-Free in Situ Monitoring of Histone Deacetylase Drug Target Engagement by Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Biotyping and Imaging

(2014) Bogdan Munteanu et al.   ANALYTICAL CHEMISTRY

DMSO-enhanced MALDI MS imaging with normalization against a deuterated standard for relative quantification of dasatinib in serial mouse pharmacology studies

(2013) Sandra Schulz et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

4-Phenyl-α-cyanocinnamic Acid Amide: Screening for a Negative Ion Matrix for MALDI-MS Imaging of Multiple Lipid Classes

(2013) Annabelle Fülöp et al.   ANALYTICAL CHEMISTRY

Quantitative Characterization of Tissue Globotetraosylceramides in a Rat Model of Polycystic Kidney Disease by PrimaDrop Sample Preparation and Indirect High-Performance Thin Layer Chromatography–Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight-Mass Spectrometry with Automated Data Acquisition

(2013) Hermelindis Ruh et al.   ANALYTICAL CHEMISTRY

Sensitive, robust and automated protein analysis of cell differentiation and of primary human blood cells by intact cell MALDI mass spectrometry biotyping

(2012) Bogdan Munteanu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

MALDIquant: a versatile R package for the analysis of mass spectrometry data

(2012) S. Gibb et al.   BIOINFORMATICS

Rapid detection of apoptosis in mammalian cells by using intact cell MALDI mass spectrometry

(2011) Hongjuan Dong et al.   ANALYST

Compelling Evidence for Lucky Survivor and Gas Phase Protonation: The Unified MALDI Analyte Protonation Mechanism

(2011) Thorsten W. Jaskolla et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Proteomic analysis of formalin-fixed paraffin-embedded tissue by MALDI imaging mass spectrometry

(2011) Rita Casadonte et al.   Nature Protocols