Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence

Pan-cancer analysis of whole genomes

(2020)   NATURE

The repertoire of mutational signatures in human cancer

(2020) Ludmil B. Alexandrov et al.   NATURE

DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers

(2020) David Mas-Ponte et al.   NATURE GENETICS

Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator

(2020) Erik N. Bergstrom et al.   BMC BIOINFORMATICS

Carcinogenicity of opium consumption

(2020) Saman Warnakulasuriya et al.   LANCET ONCOLOGY

The mutational signature profile of known and suspected human carcinogens in mice

(2020) Laura Riva et al.   NATURE GENETICS

The critical roles of somatic mutations and environmental tumor-promoting agents in cancer risk

(2020) Allan Balmain   NATURE GENETICS

Mutational Landscape of Esophageal Squamous Cell Carcinoma in an Indian Cohort

(2020) Kiran K. Mangalaparthi et al.   Frontiers in Oncology

Individual and Combined Effects of Environmental Risk Factors for Esophageal Cancer Based on Results From the Golestan Cohort Study

(2019) Mahdi Sheikh et al.   GASTROENTEROLOGY

The synergistic effect of tobacco and alcohol consumption on oral squamous cell carcinoma: a systematic review and meta-analysis

(2019) Fernanda Weber Mello et al.   Clinical Oral Investigations

Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features

(2019) Rémi Buisson et al.   SCIENCE

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

(2019) Erik N. Bergstrom et al.   BMC GENOMICS

BRCA2 loss‐of‐function germline mutations are associated with esophageal squamous cell carcinoma risk in Chinese

(2019) Josephine Mun‐Yee Ko et al.   INTERNATIONAL JOURNAL OF CANCER

A mutational signature associated with alcohol consumption and prognostically significantly mutated driver genes in esophageal squamous cell carcinoma

(2018) X C Li et al.   ANNALS OF ONCOLOGY

Epidemiology of Esophageal Squamous Cell Carcinoma

(2018) Christian C. Abnet et al.   GASTROENTEROLOGY

Strelka2: fast and accurate calling of germline and somatic variants

(2018) Sangtae Kim et al.   NATURE METHODS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

(2018) Akira Yokoyama et al.   NATURE

Somatic mutant clones colonize the human esophagus with age

(2018) Iñigo Martincorena et al.   SCIENCE

Genetic Alterations in Esophageal Tissues From Squamous Dysplasia to Carcinoma

(2017) Xi Liu et al.   GASTROENTEROLOGY

Integrated genomic characterization of oesophageal carcinoma

(2017)   NATURE

Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations

(2017) Jiang Chang et al.   Nature Communications

Conpair: concordance and contamination estimator for matched tumor–normal pairs

(2016) Ewa A. Bergmann et al.   BIOINFORMATICS

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population

(2016) Genta Sawada et al.   GASTROENTEROLOGY

Informing etiologic research priorities for squamous cell esophageal cancer in Africa: A review of setting-specific exposures to known and putative risk factors

(2016) V.A. McCormack et al.   INTERNATIONAL JOURNAL OF CANCER

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

(2016) Serena Nik-Zainal et al.   NATURE

Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors

(2016) Candace D Middlebrooks et al.   NATURE GENETICS

Mutational signatures associated with tobacco smoking in human cancer

(2016) L. B. Alexandrov et al.   SCIENCE

Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma

(2015) Ling Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Global incidence of oesophageal cancer by histological subtype in 2012

(2014) Melina Arnold et al.   GUT

Identification of genomic alterations in oesophageal squamous cell cancer

(2014) Yongmei Song et al.   NATURE

Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer

(2014) Serena Nik-Zainal et al.   NATURE GENETICS

Genetic landscape of esophageal squamous cell carcinoma

(2014) Yi-Bo Gao et al.   NATURE GENETICS

Variation in genomic landscape of clear cell renal cell carcinoma across Europe

(2014) Ghislaine Scelo et al.   Nature Communications

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Risk factors for esophageal and gastric cancers in Shanxi Province, China: A case–control study

(2011) Ying Gao et al.   Cancer Epidemiology

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations

(2011) Chen Wu et al.   NATURE GENETICS

Functional Variants in ADH1B and ALDH2 Coupled With Alcohol and Smoking Synergistically Enhance Esophageal Cancer Risk

(2009) Ri Cui et al.   GASTROENTEROLOGY

Opium, tobacco and alcohol use in relation to oesophageal squamous cell carcinoma in a high-risk area of Iran

(2008) D Nasrollahzadeh et al.   BRITISH JOURNAL OF CANCER

Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis

(2008) Stuart Macgregor et al.   HUMAN MOLECULAR GENETICS