A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers

AQP5 enriches for stem cells and cancer origins in the distal stomach

(2020) Si Hui Tan et al.   NATURE

Alteration and prognostic values of collagen gene expression in patients with gastric cancer under different treatments

(2020) Xiaoyu Gao et al.   PATHOLOGY RESEARCH AND PRACTICE

Clinical relevance of somatic mutations in main driver genes detected in gastric cancer patients by next-generation DNA sequencing

(2020) Marina V. Nemtsova et al.   Scientific Reports

Identifying multiple collagen gene family members as potential gastric cancer biomarkers using integrated bioinformatics analysis

(2020) Zhaoxing Li et al.   PeerJ

Identification of the collagen family as prognostic biomarkers and immune-associated targets in gastric cancer

(2020) Yihuan Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

High expression of bone morphogenetic protein 1 (BMP1) is associated with a poor survival rate in human gastric cancer, a dataset approaches

(2020) Jahirul Hasnat Rafi et al.   GENOMICS

A panel of collagen genes are associated with prognosis of patients with gastric cancer and regulated by microRNA-29c-3p: an integrated bioinformatics analysis and experimental validation

(2019) Qiang-nu Zhang et al.   Cancer Management and Research

FKBP10 functioned as a cancer‐promoting factor mediates cell proliferation, invasion, and migration via regulating PI3K signaling pathway in stomach adenocarcinoma

(2019) Ruo‐Gu Wang et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice

(2018) Jun Won Park et al.   MOLECULAR CARCINOGENESIS

An orthotopic mouse model of gastric cancer invasion and metastasis

(2018) Rita A. Busuttil et al.   Scientific Reports

Loss of Tight Junction Protein Claudin 18 Promotes Progressive Neoplasia Development in Mouse Stomach

(2018) Susan J. Hagen et al.   GASTROENTEROLOGY

Gastric cancer in FAP: a concerning rise in incidence

(2017) Gautam Mankaney et al.   Familial Cancer

A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer

(2017) Felipe de Sousa e Melo et al.   NATURE

Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach

(2017) Marc Leushacke et al.   NATURE CELL BIOLOGY

Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer

(2017) M Pek et al.   ONCOGENE

LGR5 promotes cancer stem cell traits and chemoresistance in cervical cancer

(2017) Hao-Zhe Cao et al.   Cell Death & Disease

LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1

(2017) Bei Wang et al.   PLoS One

Matrix metalloproteinase expression and molecular interaction network analysis in gastric cancer

(2016) Jianting Xu et al.   Oncology Letters

Lgr5-Positive Cells are Cancer-Stem-Cell-Like Cells in Gastric Cancer

(2015) Zhongli Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Genetics and Molecular Pathogenesis of Gastric Adenocarcinoma

(2015) Patrick Tan et al.   GASTROENTEROLOGY

Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

Lgr5 marks stem/progenitor cells in ovary and tubal epithelia

(2014) Annie Ng et al.   NATURE CELL BIOLOGY

Characteristics of gastric cancer in Asia

(2014) Rubayat Rahman   WORLD JOURNAL OF GASTROENTEROLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

LGR5 positivity defines stem-like cells in colorectal cancer

(2013) Daniela Hirsch et al.   CARCINOGENESIS

Differentiated Troy+ Chief Cells Act as Reserve Stem Cells to Generate All Lineages of the Stomach Epithelium

(2013) Daniel E. Stange et al.   CELL

Gastric Cancer Pathology and Underlying Molecular Mechanisms

(2013) Heike I. Grabsch et al.   DIGESTIVE SURGERY

Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers

(2013) Chen Wu et al.   GENE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Lgr5+ve Stem/Progenitor Cells Contribute to Nephron Formation during Kidney Development

(2012) Nick Barker et al.   Cell Reports

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

(2010) Nick Barker et al.   Cell Stem Cell

Spasmolytic Polypeptide-Expressing Metaplasia and Intestinal Metaplasia: Time for Reevaluation of Metaplasias and the Origins of Gastric Cancer

(2010) James R. Goldenring et al.   GASTROENTEROLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Gastric cancer

(2008) P. Lochhead et al.   BRITISH MEDICAL BULLETIN

Claudin-18 Splice Variant 2 Is a Pan-Cancer Target Suitable for Therapeutic Antibody Development

(2008) U. Sahin et al.   CLINICAL CANCER RESEARCH

Fundic Gland Polyp Dysplasia Is Common in Familial Adenomatous Polyposis

(2008) Laura K. Bianchi et al.   Clinical Gastroenterology and Hepatology