Non-genetic determinants of malignant clonal fitness at single-cell resolution

Chemotherapy induces senescence-like resilient cells capable of initiating AML recurrence

(2021) Cihangir Duy et al.   Cancer Discovery

Targeting Energy Metabolism in Cancer Stem Cells: Progress and Challenges in Leukemia and Solid Tumors

(2021) Courtney L. Jones et al.   Cell Stem Cell

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

(2020) Nemanja Despot Marjanovic et al.   CANCER CELL

Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis

(2020) Alejo E. Rodriguez-Fraticelli et al.   NATURE

Fusion partner–specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML

(2020) Hidemasa Matsuo et al.   Blood Advances

Resolving genetic heterogeneity in cancer

(2019) Samra Turajlic et al.   NATURE REVIEWS GENETICS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

HBO1 is required for the maintenance of leukaemia stem cells

(2019) Laura MacPherson et al.   NATURE

A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice

(2018) Joakim S. Dahlin et al.   BLOOD

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

Toward Minimal Residual Disease-Directed Therapy in Melanoma

(2018) Florian Rambow et al.   CELL

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

DiSNE Movie Visualization and Assessment of Clonal Kinetics Reveal Multiple Trajectories of Dendritic Cell Development

(2018) Dawn S. Lin et al.   Cell Reports

Clustering trees: a visualisation for evaluating clusterings at multiple resolutions

(2018) Luke Zappia et al.   GigaScience

Genomic encoding of transcriptional burst kinetics

(2018) Anton J. M. Larsson et al.   NATURE

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Cellular barcoding: lineage tracing, screening and beyond

(2018) Justus M. Kebschull et al.   NATURE METHODS

Association analysis identifies 65 new breast cancer risk loci

(2017) Kyriaki Michailidou et al.   NATURE

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

(2017) Sydney M. Shaffer et al.   NATURE

Tracing the origins of relapse in acute myeloid leukaemia to stem cells

(2017) Liran I. Shlush et al.   NATURE

Starcode: sequence clustering based on all-pairs search

(2015) Eduard Zorita et al.   BIOINFORMATICS

When One Mutation Is All It Takes

(2015) Mel Greaves   CANCER CELL

Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia

(2015) Min Ye et al.   Cell Stem Cell

BET inhibitor resistance emerges from leukaemia stem cells

(2015) Chun Yew Fong et al.   NATURE

Acute promyelocytic leukemia: where did we start, where are we now and the future

(2015) C C Coombs et al.   Blood Cancer Journal

Topoisomerase II and leukemia

(2014) MaryJean Pendleton et al.   Annals of the New York Academy of Sciences

Cellular barcoding: A technical appraisal

(2014) Shalin H. Naik et al.   EXPERIMENTAL HEMATOLOGY

DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly

(2014) Ilari Scheinin et al.   GENOME RESEARCH

Diverse and heritable lineage imprinting of early haematopoietic progenitors

(2013) Shalin H. Naik et al.   NATURE

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Cell of origin determines clinically relevant subtypes of MLL-rearranged AML

(2012) A V Krivtsov et al.   LEUKEMIA

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Mouse models of human AML accurately predict chemotherapy response

(2009) J. Zuber et al.   GENES & DEVELOPMENT

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL