SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia

(2020) Feng Pan et al.   RADIOLOGY

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Animal models of mechanisms of SARS‐CoV‐2 infection and COVID‐19 pathology

(2020) Simon J. Cleary et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pathogenesis of SARS-CoV-2 in transgenic mice expressing human angiotensin-converting enzyme 2

(2020) Ren-Di Jiang et al.   CELL

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

(2020) Pierre Bost et al.   CELL

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

(2020) Zhuo Zhou et al.   Cell Host & Microbe

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19

(2020) Annsea Park et al.   Cell Host & Microbe

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis

(2020) Shi-Hui Sun et al.   Cell Host & Microbe

Characterization of an asymptomatic cohort of SARS-COV-2 infected individuals outside of Wuhan, China

(2020) Yubo Wang et al.   CLINICAL INFECTIOUS DISEASES

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients

(2020) Xiaohua Chen et al.   CLINICAL INFECTIOUS DISEASES

Extra-respiratory manifestations of COVID-19

(2020) Chih-Cheng Lai et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Alterations in Smell or Taste in Mildly Symptomatic Outpatients With SARS-CoV-2 Infection

(2020) Giacomo Spinato et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19

(2020) Yang Yang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

(2020) Linlin Bao et al.   NATURE

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

(2020) Barry Rockx et al.   SCIENCE

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

(2020) Jing Liu et al.   EBioMedicine

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

(2020) Ahmed O. Hassan et al.   CELL

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling

(2020) Benjamin Israelow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis

(2020) Leiwen Fu et al.   JOURNAL OF INFECTION

COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

(2020) Robert Lorenz Chua et al.   NATURE BIOTECHNOLOGY

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

(2020) Aaron J. Wilk et al.   NATURE MEDICINE

Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor

(2020) Yanwei Li et al.   PHARMACOLOGICAL RESEARCH

Decreased T cell populations contribute to the increased severity of COVID-19

(2020) Rui Liu et al.   CLINICA CHIMICA ACTA

Shared and Distinct Functions of Type I and Type III Interferons

(2019) Helen M. Lazear et al.   IMMUNITY

Distinct Roles of Interferon Alpha and Beta in Controlling Chikungunya Virus Replication and Modulating Neutrophil-Mediated Inflammation

(2019) Lindsey E. Cook et al.   JOURNAL OF VIROLOGY

Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

(2016) Cherie T. Ng et al.   CELL

Parsing the Interferon Transcriptional Network and Its Disease Associations

(2016) Sara Mostafavi et al.   CELL

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

Enhancing dengue virus maturation using a stable furin over-expressing cell line

(2016) Swati Mukherjee et al.   VIROLOGY

Blockade of Interferon Beta, but Not Interferon Alpha, Signaling Controls Persistent Viral Infection

(2015) Cherie T. Ng et al.   Cell Host & Microbe

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses

(2015) Ruijie Liu et al.   NUCLEIC ACIDS RESEARCH

Engineering Adolescence

(2014) Xiulan Yang et al.   CIRCULATION RESEARCH

Comparative study of threeflexiVentsystem configurations using mechanical test loads

(2014) Annette Robichaud et al.   EXPERIMENTAL LUNG RESEARCH

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2

(2008) J. Netland et al.   JOURNAL OF VIROLOGY