Recombinant ACE2 Expression Is Required for SARS-CoV-2 To Infect Primary Human Endothelial Cells and Induce Inflammatory and Procoagulative Responses

Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury

(2020) Terren K Niethamer et al.   eLife

COVID-19 and its implications for thrombosis and anticoagulation

(2020) Jean Marie Connors et al.   BLOOD

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

(2020) Yixuan J. Hou et al.   CELL

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

(2020) Soeren Lukassen et al.   EMBO JOURNAL

Electron microscopy of SARS-CoV-2: a challenging task

(2020) Cynthia S Goldsmith et al.   LANCET

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dysfunctional Coagulation in COVID-19: From Cell to Bedside

(2020) Jie Wang et al.   ADVANCES IN THERAPY

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

(2020) Eugenio D. Hottz et al.   BLOOD

Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration

(2018) Chhinder P. Sodhi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

E-selectin inhibition with GMI-1271 decreases venous thrombosis without profoundly affecting tail vein bleeding in a mouse model

(2017) Dorian Culmer et al.   THROMBOSIS AND HAEMOSTASIS

ACE2 Antagonizes VEGFa to Reduce Vascular Permeability During Acute Lung Injury

(2016) Xiaobo Yu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Pulmonary Angiotensin-Converting Enzyme 2 (ACE2) and Inflammatory Lung Disease

(2016) Hongpeng Jia   SHOCK

Endothelial cell control of thrombosis

(2015) Jonathan W. Yau et al.   BMC Cardiovascular Disorders

ACE2 and Ang-(1–7) protect endothelial cell function and prevent early atherosclerosis by inhibiting inflammatory response

(2015) Yue-Hui Zhang et al.   INFLAMMATION RESEARCH

ACE2 and AT4R are present in diseased human blood vessels

(2015) A Zulli et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Angiotensin-Converting Enzyme 2 Is a Critical Determinant of Angiotensin II–Induced Loss of Vascular Smooth Muscle Cells and Adverse Vascular Remodeling

(2014) Vaibhav B. Patel et al.   HYPERTENSION

Protective Role of the ACE2/Ang-(1–9) Axis in Cardiovascular Remodeling

(2012) María Paz Ocaranza et al.   International Journal of Hypertension

Role of HIF-1α in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells

(2009) Ruifeng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY