Anticancer Properties of Eugenol: A Review

Treatment with Uncaria tomentosa Promotes Apoptosis in B16-BL6 Mouse Melanoma Cells and Inhibits the Growth of B16-BL6 Tumours

(2021) Ali Zari et al.   MOLECULES

Recent Advances in Nanotechnology for the Treatment of Melanoma

(2021) Roberta Cassano et al.   MOLECULES

Molecules Present in Plant Essential Oils for Prevention and Treatment of Colorectal Cancer (CRC)

(2021) Giovannamaria Petrocelli et al.   MOLECULES

Biological Properties and Prospects for the Application of Eugenol—A Review

(2021) Magdalena Ulanowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Eugenol-Induced Autophagy and Apoptosis in Breast Cancer Cells via PI3K/AKT/FOXO3a Pathway Inhibition

(2021) Mashan L. Abdullah et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Eugenol modulates genomic methylation and inactivates breast cancer‐associated fibroblasts through E2F1‐dependent downregulation of DNMT1/DNMT3A

(2021) Layla A. Al‐Kharashi et al.   MOLECULAR CARCINOGENESIS

Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review

(2021) Muhammad Farrukh Nisar et al.   Oxidative Medicine and Cellular Longevity

Syzygium aromaticum L. (Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological and Toxicological Activities

(2020) Gaber El-Saber Batiha et al.   Biomolecules

Computational analysis of eugenol inhibitory activity in lipoxygenase and cyclooxygenase pathways

(2020) Francisco das Chagas Pereira de Andrade et al.   Scientific Reports

Co-Delivery of Eugenol and Dacarbazine by Hyaluronic Acid-Coated Liposomes for Targeted Inhibition of Survivin in Treatment of Resistant Metastatic Melanoma

(2019) Harshita Mishra et al.   Pharmaceutics

Eugenol allergy mimicking recurrent aphthous stomatitis and burning mouth syndrome

(2019) Francisco J. Navarro Triviño et al.   CONTACT DERMATITIS

Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation

(2019) Moustafa Fathy et al.   MOLECULES

Emergent Nanotechnological Strategies for Systemic Chemotherapy against Melanoma

(2019) Jacinta Oliveira Pinho et al.   Nanomaterials

Chemical Composition, Antioxidant and Anti-melanogenic Activities of Essential Oils from Chrysanthemum boreale  Makino at Different Harvesting Stages

(2018) Do-Yoon Kim et al.   CHEMISTRY & BIODIVERSITY

Eugenol derivatives: synthesis, characterization, and evaluation of antibacterial and antioxidant activities

(2018) Francisco Felipe Maia da Silva et al.   Chemistry Central Journal

Lack of postexposure analgesic efficacy of low concentrations of eugenol in zebrafish

(2018) Bernardo Baldisserotto et al.   VETERINARY ANAESTHESIA AND ANALGESIA

Oregano Essential Oil Attenuates RAW264.7 Cells from Lipopolysaccharide-Induced Inflammatory Response through Regulating NADPH Oxidase Activation-Driven Oxidative Stress

(2018) Chuanshang Cheng et al.   MOLECULES

Anti-metastatic and anti-proliferative activity of eugenol against triple negative and HER2 positive breast cancer cells

(2018) Mashan L. Abdullah et al.   BMC Complementary and Alternative Medicine

An Overview on the Anti-inflammatory Potential and Antioxidant Profile of Eugenol

(2018) Joice Nascimento Barboza et al.   Oxidative Medicine and Cellular Longevity

Inflammation and cancer

(2018) Mariko Murata   Environmental Health and Preventive Medicine

Effects of Caralluma russeliana stem extract on some physiological parameters in streptozotocin-induced diabetic male rats

(2018) Talal A Zari et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Antioxidant and antibacterial activities of Pelargonium asperum and Ormenis mixta essential oils and their synergistic antibacterial effect

(2017) Wessal Ouedrhiri et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Regulation of Chemokine–Receptor Interactions and Functions

(2017) Martin Stone   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Essential oil of Artemisia argyi suppresses inflammatory responses by inhibiting JAK/STATs activation

(2017) Lin-Lin Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antibacterial activity and interactions of plant essential oil combinations against Gram-positive and Gram-negative bacteria

(2017) Cristina Anamaria Semeniuc et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Eugenol potentiates cisplatin anti-cancer activity through inhibition of ALDH-positive breast cancer stem cells and the NF-κB signaling pathway

(2017) Syed S. Islam et al.   MOLECULAR CARCINOGENESIS

Anesthetic Agents of Plant Origin: A Review of Phytochemicals with Anesthetic Activity

(2017) Hironori Tsuchiya   MOLECULES

The Dual Antioxidant/Prooxidant Effect of Eugenol and Its Action in Cancer Development and Treatment

(2017) Daniel Bezerra et al.   Nutrients

Essential oil eugenol: sources, extraction techniques and nutraceutical perspectives

(2017) Anees Ahmed Khalil et al.   RSC Advances

Dacarbazine nanoparticle topical delivery system for the treatment of melanoma

(2017) Abdul Hafeez et al.   Scientific Reports

Tumor suppressive roles of eugenol in human lung cancer cells

(2017) Li Fangjun et al.   Thoracic Cancer

Variability of Chemical Compositions and Antimicrobial and Antioxidant Activities of Ruta chalepensis Leaf Essential Oils from Three Palestinian Regions

(2017) Nidal Jaradat et al.   Biomed Research International

In vitro synergistic antibacterial activity of the essential oil from Zingiber cassumunar Roxb against extensively drug-resistant Acinetobacter baumannii strains

(2017) Wongwarut Boonyanugomol et al.   Journal of Infection and Public Health

Constitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production

(2017) Fanny Polesso et al.   Scientific Reports

Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation

(2016) Irina Tsoy Nizamutdinova et al.   Aging-US

Medicinal attributes of major phenylpropanoids present in cinnamon

(2016) Uma Kant Sharma et al.   BMC Complementary and Alternative Medicine

Biological and Nonbiological Antioxidant Activity of Some Essential Oils

(2016) Renato Pérez-Rosés et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Eugenol Toxicity in Human Dental Pulp Fibroblasts of Primary Teeth

(2016) Maria Escobar-García et al.   Journal of Clinical Pediatric Dentistry

Roles for E-cadherin cell surface regulation in cancer

(2016) Yuliya I. Petrova et al.   MOLECULAR BIOLOGY OF THE CELL

MicroRNA-218 inhibits EMT, migration and invasion by targeting SFMBT1 and DCUN1D1 in cervical cancer

(2016) Zhaojing Jiang et al.   Oncotarget

Anti-inflammatory effects of eugenol on lipopolysaccharide-induced inflammatory reaction in acute lung injury via regulating inflammation and redox status

(2015) Xianfeng Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cancer of the cervix uteri

(2015) Adriana Bermudez et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Experimental evaluation of anti-inflammatory, antinociceptive and antipyretic activities of clove oil in mice

(2015) Yousef A. Taher et al.   Libyan Journal of Medicine

A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition

(2015) Wenting Xu et al.   Cell Adhesion & Migration

Non-steroidal anti inflammatory drugs, glucocorticoids and disease modifying anti-rheumatic drugs for the management of rheumatoid arthritis before and during pregnancy

(2014) Bonnie L. Bermas   CURRENT OPINION IN RHEUMATOLOGY

Anti-Inflammatory Effects of Apigenin in Lipopolysaccharide-Induced Inflammatory in Acute Lung Injury by Suppressing COX-2 and NF-kB Pathway

(2014) Jing Wang et al.   INFLAMMATION

Citral and eugenol modulate DNA damage and pro-inflammatory mediator genes in murine peritoneal macrophages

(2014) Marilia de Paula Porto et al.   MOLECULAR BIOLOGY REPORTS

Does antioxidant properties of the main component of essential oil reflect its antioxidant properties? The comparison of antioxidant properties of essential oils and their main components

(2014) Andrzej L. Dawidowicz et al.   NATURAL PRODUCT RESEARCH

Evaluation Physical Characteristics and Comparison Antimicrobial and Anti-Inflammation Potentials of Dental Root Canal Sealers Containing Hinokitiol In Vitro

(2014) Yin-Hua Shih et al.   PLoS One

Eugenol triggers apoptosis in breast cancer cells through E2F1/survivin down-regulation

(2013) Ibtehaj Al-Sharif et al.   BMC CANCER

TACC3 promotes epithelial–mesenchymal transition (EMT) through the activation of PI3K/Akt and ERK signaling pathways

(2013) Geun-Hyoung Ha et al.   CANCER LETTERS

A Review on Anti-Inflammatory Activity of Monoterpenes

(2013) Rita de Cássia da Silveira e Sá et al.   MOLECULES

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

DNA Damage in Inflammation-Related Carcinogenesis and Cancer Stem Cells

(2013) Shiho Ohnishi et al.   Oxidative Medicine and Cellular Longevity

Drug Screening for Autophagy Inhibitors Based on the Dissociation of Beclin1-Bcl2 Complex Using BiFC Technique and Mechanism of Eugenol on Anti-Influenza A Virus Activity

(2013) Jian-Ping Dai et al.   PLoS One

The Antifungal Eugenol Perturbs Dual Aromatic and Branched-Chain Amino Acid Permeases in the Cytoplasmic Membrane of Yeast

(2013) Emad Darvishi et al.   PLoS One

Antioxidant and Antimicrobial Activities of Clove Bud Essential Oil and Eugenol Nanoparticles in Alcohol-Free Microemulsion

(2012) Said Fatouh Hamed et al.   Journal of Oleo Science

Loss of E-cadherin and Acquisition of Vimentin in Epithelial-Mesenchymal Transition are Noble Indicators of Uterine Cervix Cancer Progression

(2012) Na-Hye Myong   Korean Journal of Pathology

Antiproliferative and Molecular Mechanism of Eugenol-Induced Apoptosis in Cancer Cells

(2012) Saravana Kumar Jaganathan et al.   MOLECULES

Eugenol—From the Remote Maluku Islands to the International Market Place: A Review of a Remarkable and Versatile Molecule

(2012) Guy P. Kamatou et al.   MOLECULES

Eugenol Enhances the Chemotherapeutic Potential of Gemcitabine and Induces Anticarcinogenic and Anti-inflammatory Activity in Human Cervical Cancer Cells

(2011) Arif Hussain et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Antioxidant Activity of Eugenol: A Structure–Activity Relationship Study

(2011) İlhami Gülçin   JOURNAL OF MEDICINAL FOOD

Apoptotic effect of eugenol in human colon cancer cell lines

(2010) Saravana Kumar Jaganathan et al.   CELL BIOLOGY INTERNATIONAL

Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG

(2010) Palrasu Manikandan et al.   LIFE SCIENCES

Eugenol inhibits cell proliferation via NF-κB suppression in a rat model of gastric carcinogenesis induced by MNNG

(2009) P. Manikandan et al.   INVESTIGATIONAL NEW DRUGS

Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis

(2009) Gurpreet Kaur et al.   MOLECULAR CARCINOGENESIS

Anti-inflammatory and antinociceptive activities A of eugenol essential oil in experimental animal models

(2009) Apparecido N. Daniel et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats

(2009) Baskaran Yogalakshmi et al.   TOXICOLOGY

Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs

(2007) Yu-Tang Tung et al.   BIORESOURCE TECHNOLOGY

Biological effects of essential oils – A review

(2007) F. Bakkali et al.   FOOD AND CHEMICAL TOXICOLOGY

Clastogenic activity of seven endodontic medications used in dental practice in human dental pulp cells

(2007) Hitomi Someya et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS