Eugenol modulates genomic methylation and inactivates breast cancer‐associated fibroblasts through E2F1‐dependent downregulation of DNMT1/DNMT3A

Effects of 5-Aza-2′-deoxycytidine (decitabine) on gene expression

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Turning foes to friends: targeting cancer-associated fibroblasts

(2018) Xueman Chen et al.   NATURE REVIEWS DRUG DISCOVERY

Eugenol potentiates cisplatin anti-cancer activity through inhibition of ALDH-positive breast cancer stem cells and the NF-κB signaling pathway

(2017) Syed S. Islam et al.   MOLECULAR CARCINOGENESIS

The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts

(2017) Layla A. Al-Kharashi et al.   Oncotarget

Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation

(2016) Qian Xiao et al.   CANCER RESEARCH

Differential expression of the epigenetic methylation-related protein DNMT1 by breast cancer molecular subtype and stromal histology

(2016) Eunah Shin et al.   Journal of Translational Medicine

Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts

(2015) Jean Albrengues et al.   Nature Communications

Epigenetic and transcriptional determinants of the human breast

(2015) Philippe Gascard et al.   Nature Communications

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

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Curcumin Triggers p16-Dependent Senescence in Active Breast Cancer-Associated Fibroblasts and Suppresses Their Paracrine Procarcinogenic Effects

(2015) Siti-Fauziah Hendrayani et al.   NEOPLASIA

The Cytokine IL-6 Reactivates Breast Stromal Fibroblasts through Transcription Factor STAT3-dependent Up-regulation of the RNA-binding Protein AUF1

(2014) Siti-Fauziah Hendrayani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caffeine Mediates Sustained Inactivation of Breast Cancer-Associated Myofibroblasts via Up-Regulation of Tumor Suppressor Genes

(2014) Mysoon M. Al-Ansari et al.   PLoS One

Eugenol triggers apoptosis in breast cancer cells through E2F1/survivin down-regulation

(2013) Ibtehaj Al-Sharif et al.   BMC CANCER

Methylation profiling ofSOCS1,SOCS2,SOCS3,CISHandSHP1in Philadelphia-negative myeloproliferative neoplasm

(2013) Min Yue Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Eugenol—From the Remote Maluku Islands to the International Market Place: A Review of a Remarkable and Versatile Molecule

(2012) Guy P. Kamatou et al.   MOLECULES

Eugenol inhibits cell proliferation via NF-κB suppression in a rat model of gastric carcinogenesis induced by MNNG

(2009) P. Manikandan et al.   INVESTIGATIONAL NEW DRUGS

Breast Carcinoma-Associated Fibroblasts and Their Counterparts Display Neoplastic-Specific Changes

(2008) N. M. Hawsawi et al.   CANCER RESEARCH