Phytochemistry, Ethnopharmacological Uses, Biological Activities, and Therapeutic Applications of Cassia obtusifolia L.: A Comprehensive Review

Neuroprotective Effect of Aurantio-Obtusin, a Putative Vasopressin V1A Receptor Antagonist, on Transient Forebrain Ischemia Mice Model

(2021) Pradeep Paudel et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hepatoprotective effects of Cassia semen ethanol extract on non-alcoholic fatty liver disease in experimental rat

(2019) Yuanyuan Meng et al.   PHARMACEUTICAL BIOLOGY

In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds

(2019) Pradeep Paudel et al.   ACS Omega

Two new naphthalenic lactone glycosides from Cassia obtusifolia L. seeds

(2018) Srijan Shrestha et al.   ARCHIVES OF PHARMACAL RESEARCH

Anthraquinone and naphthopyrone glycosides from Cassia obtusifolia seeds mediate hepatoprotection via Nrf2-mediated HO-1 activation and MAPK modulation

(2018) Pradeep Paudel et al.   ARCHIVES OF PHARMACAL RESEARCH

Enzymatic purification and structure characterization of glucuronoxylan from water extract of Cassia obtusifolia seeds

(2018) Lei Feng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Two new naphthalene glycosides from the seeds of Cassia obtusifolia

(2018) Xu Pang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Aurantio-obtusin, an anthraquinone from cassiae semen, ameliorates lung inflammatory responses

(2018) Ki Sun Kwon et al.   PHYTOTHERAPY RESEARCH

Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-κB Pathway

(2018) Jingyi Hou et al.   MOLECULES

Toralactone glycoside in Cassia obtusifolia mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism

(2017) Yongtaek Seo et al.   FOOD RESEARCH INTERNATIONAL

Hepatoprotective effect of Cassia obtusifolia seed extract and constituents against oxidative damage induced by tert -butyl hydroperoxide in human hepatic HepG2 cells

(2017) Md Yousof Ali et al.   JOURNAL OF FOOD BIOCHEMISTRY

Cassiae semen: A review of its phytochemistry and pharmacology

(2017) Xiaoxv Dong et al.   Molecular Medicine Reports

Structure Related Inhibition of Enzyme Systems in Cholinesterases and BACE1 In Vitro by Naturally Occurring Naphthopyrone and Its Glycosides Isolated from Cassia obtusifolia

(2017) Srijan Shrestha et al.   MOLECULES

Antibacterial activity of six medicinal Cameroonian plants against Gram-positive and Gram-negative multidrug resistant phenotypes

(2016) Igor K. Voukeng et al.   BMC Complementary and Alternative Medicine

Fractionation, physicochemical property and immunological activity of polysaccharides from Cassia obtusifolia

(2016) Lei Feng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases

(2016) Hyun Ah Jung et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cassia obtusifolia seed ameliorates amyloid β-induced synaptic dysfunction through anti-inflammatory and Akt/GSK-3β pathways

(2016) Jee Hyun Yi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Promising Inhibitory Effects of Anthraquinones, Naphthopyrone, and Naphthalene Glycosides, from Cassia obtusifolia on α-Glucosidase and Human Protein Tyrosine Phosphatases 1B

(2016) Hyun Jung et al.   MOLECULES

Changes in Plasma Lipid Levels and Antioxidant Activities in Rats after Supplementation of Obtusifolin

(2016) Si-Yi Zhuang et al.   PLANTA MEDICA

Simultaneous determination of seven anthraquinones in rat plasma by Ultra High Performance Liquid Chromatography–tandem Mass Spectrometry and pharmacokinetic study after oral administration of Semen Cassiae extract

(2015) Chunjuan Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Discrimination of Semen cassiae from two related species based on the multivariate analysis of high-performance liquid chromatography fingerprints

(2015) Liying Tang et al.   JOURNAL OF SEPARATION SCIENCE

A new anthraquinone from seed ofCassia obtusifolia

(2015) Bao-jun Shi et al.   NATURAL PRODUCT RESEARCH

Five new anthraquinones from the seed of Cassia obtusifolia

(2014) Yi-Long Xu et al.   ARCHIVES OF PHARMACAL RESEARCH

Anti-allodynic Effects of Obtusifolin and Gluco-Obtusifolin against Inflammatory and Neuropathic Pain

(2014) Zhi-Wei He et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Isolation, structure modeling and function characterization of a trypsin inhibitor from Cassia obtusifolia

(2014) Zubi Liu et al.   BIOTECHNOLOGY LETTERS

Structure and activities of a novel heteroxylan from Cassia obtusifolia seeds and its sulfated derivative

(2014) Qifei Cong et al.   CARBOHYDRATE RESEARCH

Obtusifolin Treatment Improves Hyperlipidemia and Hyperglycemia: Possible Mechanism Involving Oxidative Stress

(2014) Yu Tang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Aurantio-Obtusin Stimulates Chemotactic Migration and Differentiation of MC3T3-E1 Osteoblast Cells

(2014) Chethala Vishnuprasad et al.   PLANTA MEDICA

Composition, characteristics, and in-vitro physiological effects of the water-soluble polysaccharides from Cassia seed

(2012) Ya-Ling Huang et al.   FOOD CHEMISTRY

The Protective Effect ofCassia obtusifoliaon DSS-Induced Colitis

(2011) Su-Jin Kim et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Three new acetylated benzyl-beta-resorcylate glycosides from Cassia obtusifolia

(2011) Xiaohui Wu et al.   FITOTERAPIA

Antioxidant Potential and Type II Diabetes-Related Enzyme Inhibition of Cassia obtusifolia L.: Effect of Indigenous Processing Methods

(2011) Vellingiri Vadivel et al.   Food and Bioprocess Technology

Acetylated anthraquinone glycosides fromCassia obtusifolia

(2011) Xiao-Hui Wu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Structure elucidation of a sodium salified anthraquinone from the seeds of Cassia obtusifolia by NMR technique assisted with acid-alkali titration

(2011) Chen Zhang et al.   MAGNETIC RESONANCE IN CHEMISTRY

Anthraquinones, sterols, triterpenoids and xanthones from Cassia obtusifolia

(2010) Sylvain Valère T. Sob et al.   BIOCHEMICAL SYSTEMATICS AND ECOLOGY

Benzyl-β-resorcylates from Cassia obtusifolia

(2010) Xiao-Hui Wu et al.   FITOTERAPIA

Alaternin attenuates delayed neuronal cell death induced by transient cerebral hypoperfusion in mice

(2010) Bum Young Shin et al.   FOOD AND CHEMICAL TOXICOLOGY

Cassiae semen, a seed of Cassia obtusifolia, has neuroprotective effects in Parkinson’s disease models

(2010) Mi Sun Ju et al.   FOOD AND CHEMICAL TOXICOLOGY

The neuroprotective effects of the seeds of Cassia obtusifolia on transient cerebral global ischemia in mice

(2009) Dong Hyun Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Processing Scale-Up of Sicklepod (Senna obtusifoliaL.) Seed

(2009) Rogers E. Harry-O’Kuru et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Gluco-obtusifolin and Its Aglycon, Obtusifolin, Attenuate Scopolamine-Induced Memory Impairment

(2009) Dong Hyun Kim et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

A new anthraquinone glycoside from seeds of Cassia obtusifolia

(2008) Li Ying Tang et al.   CHINESE CHEMICAL LETTERS

The Seed Extract of Cassia obtusifolia Offers Neuroprotection to Mouse Hippocampal Cultures

(2008) Benjamin D. Drever et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Larvicidal and oviposition activity of Cassia obtusifolia Linn (Family: Leguminosae) leaf extract against malarial vector, Anopheles stephensi Liston (Diptera: Culicidae)

(2008) S. Rajkumar et al.   PARASITOLOGY RESEARCH

A xanthone and a polyketide derivative from the leaves of Cassia obtusifolia (Leguminosae)

(2008) Sylvain Valère T. Sob et al.   TETRAHEDRON