Structure Related Inhibition of Enzyme Systems in Cholinesterases and BACE1 In Vitro by Naturally Occurring Naphthopyrone and Its Glycosides Isolated from Cassia obtusifolia

Asp32 and Asp228 determine the selective inhibition of BACE1 as shown by docking and molecular dynamics simulations

(2016) Maricarmen Hernández-Rodríguez et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases

(2016) Hyun Ah Jung et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cassia obtusifolia seed ameliorates amyloid β-induced synaptic dysfunction through anti-inflammatory and Akt/GSK-3β pathways

(2016) Jee Hyun Yi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Promising Inhibitory Effects of Anthraquinones, Naphthopyrone, and Naphthalene Glycosides, from Cassia obtusifolia on α-Glucosidase and Human Protein Tyrosine Phosphatases 1B

(2016) Hyun Jung et al.   MOLECULES

From plants to pharmacy shelf: natural products revival

(2016) Milen I. Georgiev   PHYTOCHEMISTRY REVIEWS

Anti-Alzheimer's disease potential of coumarins from Angelica decursiva and Artemisia capillaris and structure-activity analysis

(2016) Md. Yousof Ali et al.   Asian Pacific Journal of Tropical Medicine

Discovery of polymethoxyflavones from black ginger ( Kaempferia parviflora ) as potential β-secretase (BACE1) inhibitors

(2016) Kumju Youn et al.   Journal of Functional Foods

Plant-derived epigenetic modulators for cancer treatment and prevention

(2014) Michael Schnekenburger et al.   BIOTECHNOLOGY ADVANCES

From nature to bedside: Pro-survival and cell death mechanisms as therapeutic targets in cancer treatment

(2014) Claudia Cerella et al.   BIOTECHNOLOGY ADVANCES

Natural products from resurrection plants: Potential for medical applications

(2014) Tsanko S. Gechev et al.   BIOTECHNOLOGY ADVANCES

Differential Effects of Methoxy Group on the Interaction of Curcuminoids with Two Major Ligand Binding Sites of Human Serum Albumin

(2014) Hiroki Sato et al.   PLoS One

Evaluation and Structure-Activity Relationship Analysis of a New Series of Arylnaphthalene lignans as Potential Anti-Tumor Agents

(2014) Jiaoyang Luo et al.   PLoS One

Effects of the methoxy group in the side chain of debromoaplysiatoxin on its tumor-promoting and anti-proliferative activities

(2013) Ryo C. Yanagita et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effects of C-glycosylation on anti-diabetic, anti-Alzheimer’s disease and anti-inflammatory potential of apigenin

(2013) Jae Sue Choi et al.   FOOD AND CHEMICAL TOXICOLOGY

Elucidating the catalytic mechanism of β-secretase (BACE1): A quantum mechanics/molecular mechanics (QM/MM) approach

(2013) Arghya Barman et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Structure–activity relationship investigation of methoxy substitution on anticancer pyrimido[4,5-c]quinolin-1(2H)-ones

(2013) Kamel Metwally et al.   MEDICINAL CHEMISTRY RESEARCH

Molecular Docking: A Powerful Approach for Structure-Based Drug Discovery

(2012) Xuan-Yu Meng et al.   Current Computer-Aided Drug Design

Molecular docking for virtual screening of natural product databases

(2011) Dik-Lung Ma et al.   Chemical Science

Selective Cholinesterase Inhibitory Activities of a New Monoterpene Diglycoside and Other Constituents from Nelumbo nucifera Stamens

(2010) Hyun Ah Jung et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cassiae semen, a seed of Cassia obtusifolia, has neuroprotective effects in Parkinson’s disease models

(2010) Mi Sun Ju et al.   FOOD AND CHEMICAL TOXICOLOGY

The Seed Extract of Cassia obtusifolia Offers Neuroprotection to Mouse Hippocampal Cultures

(2008) Benjamin D. Drever et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES