Cortical Dysplasia in Rats Provokes Neurovascular Alterations, GLUT1 Dysfunction, and Metabolic Disturbances That Are Sustained Post-Seizure Induction

Heat Shock Proteins Accelerate the Maturation of Brain Endothelial Cell Glucocorticoid Receptor in Focal Human Drug-Resistant Epilepsy

(2020) Mohammed Hossain et al.   MOLECULAR NEUROBIOLOGY

Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options

(2020) Wolfgang Löscher et al.   PHARMACOLOGICAL REVIEWS

The Roof is Leaking and a Storm is Raging: Repairing the Blood–Brain Barrier in the Fight Against Epilepsy

(2019) J.A. Gorter et al.   Epilepsy Currents

Neurovascular Drug Biotransformation Machinery in Focal Human Epilepsies: Brain CYP3A4 Correlates with Seizure Frequency and Antiepileptic Drug Therapy

(2019) Sherice Williams et al.   MOLECULAR NEUROBIOLOGY

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment

(2018) Candice E. Van Skike et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Glia-neuron energy metabolism in health and diseases: New insights into the role of nervous system metabolic transporters

(2018) Mithilesh Kumar Jha et al.   EXPERIMENTAL NEUROLOGY

Treatment with lacosamide impedes generalized seizures in a rodent model of cortical dysplasia

(2017) Ashley D. Nemes et al.   EPILEPSIA

Growth Associated Protein 43 (GAP-43) as a Novel Target for the Diagnosis, Treatment and Prevention of Epileptogenesis

(2017) Ashley D. Nemes et al.   Scientific Reports

Matrix Metalloproteinase 9 in Epilepsy: The Role of Neuroinflammation in Seizure Development

(2016) Elżbieta Bronisz et al.   MEDIATORS OF INFLAMMATION

Distinct Expression of Various Angiogenesis Factors in Mice Brain After Whole-Brain Irradiation by X-ray

(2016) Zhezhi Deng et al.   NEUROCHEMICAL RESEARCH

Somatic Mutations in theMTORgene cause focal cortical dysplasia type IIb

(2015) Mitsuko Nakashima et al.   ANNALS OF NEUROLOGY

PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia

(2015) Laura A. Jansen et al.   BRAIN

Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: An in vitro study

(2015) Chaitali Ghosh et al.   EPILEPSIA

Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy

(2015) Jae Seok Lim et al.   NATURE MEDICINE

The search for circulating epilepsy biomarkers

(2014) Manu Hegde et al.   Biomarkers in Medicine

Blood-brain barrier dysfunction can contribute to pharmacoresistance of seizures

(2014) Seda Salar et al.   EPILEPSIA

GLUT1 deficiency syndrome into adulthood: a follow-up study

(2014) W. G. Leen et al.   JOURNAL OF NEUROLOGY

Role of blood–brain barrier in temporal lobe epilepsy and pharmacoresistance

(2014) E.A. van Vliet et al.   NEUROSCIENCE

Lactate promotes resistance to glucose starvation via upregulation of Bcl-2 mediated by mTOR activation

(2014) CHEN HUANG et al.   ONCOLOGY REPORTS

Perfusion Imaging of Focal Cortical Dysplasia Using Arterial Spin Labeling

(2013) Pia Wintermark et al.   JOURNAL OF CHILD NEUROLOGY

Neuropathology of the blood–brain barrier and pharmaco-resistance in human epilepsy

(2012) Joan Y. W. Liu et al.   BRAIN

Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions

(2012) Anna Raabe et al.   EPILEPSIA

Glut1 deficiency (G1D): Epilepsy and metabolic dysfunction in a mouse model of the most common human phenotype

(2012) Isaac Marin-Valencia et al.   NEUROBIOLOGY OF DISEASE

Peri-infarct blood–brain barrier dysfunction facilitates induction of spreading depolarization associated with epileptiform discharges

(2012) E.G. Lapilover et al.   NEUROBIOLOGY OF DISEASE

Molecular cascades that mediate the influence of inflammation on epilepsy

(2011) Alon Friedman et al.   EPILEPSIA

Blood-brain barrier dysfunction, status epilepticus, seizures, and epilepsy: A puzzle of a chicken and egg?

(2011) Alon Friedman   EPILEPSIA

Epilepsy and brain inflammation

(2011) Annamaria Vezzani et al.   EXPERIMENTAL NEUROLOGY

Engaging neuroscience to advance translational research in brain barrier biology

(2011) Edward A. Neuwelt et al.   NATURE REVIEWS NEUROSCIENCE

Temporal changes in mRNA expression of the brain nutrient transporters in the lithium–pilocarpine model of epilepsy in the immature and adult rat

(2011) Claire Leroy et al.   NEUROBIOLOGY OF DISEASE

Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy

(2011) Fredrik Lauritzen et al.   NEUROBIOLOGY OF DISEASE

Blood-brain barrier damage and brain penetration of antiepileptic drugs: Role of serum proteins and brain edema

(2009) Nicola Marchi et al.   EPILEPSIA

Blood–brain barrier breakdown as a novel mechanism underlying cerebral hyperperfusion syndrome

(2009) Sebastian Ivens et al.   JOURNAL OF NEUROLOGY

The Mammalian Target of Rapamycin Signaling Pathway Mediates Epileptogenesis in a Model of Temporal Lobe Epilepsy

(2009) L.-H. Zeng et al.   JOURNAL OF NEUROSCIENCE

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

The Tuberous Sclerosis Complex Regulates Trafficking of Glucose Transporters and Glucose Uptake

(2008) Xiuyun Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

Single injection of a low dose of pentylenetetrazole leads to epileptogenesis in an animal model of cortical dysplasia

(2008) Roger O. Oghlakian et al.   EPILEPSIA

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Blood-brain barrier disruption in post-traumatic epilepsy

(2007) O Tomkins et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY