circPTEN1, a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling

Comprehensive landscape and future perspectives of circular RNAs in colorectal cancer

(2021) Fei Long et al.   Molecular Cancer

CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity

(2021) Zhao-Ru Dong et al.   Molecular Cancer

Circular RNA circIKBKB promotes breast cancer bone metastasis through sustaining NF-κB/bone remodeling factors signaling

(2021) Yingru Xu et al.   Molecular Cancer

CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability

(2021) Yu Zhang et al.   Molecular Cancer

TGF-β Signaling

(2020) Kalliopi Tzavlaki et al.   Biomolecules

circRNA_100859 functions as an oncogene in colon cancer by sponging the miR-217-HIF-1α pathway

(2020) Peng Zhou et al.   Aging-US

Circular RNA CDR1as disrupts the p53/MDM2 complex to inhibit Gliomagenesis

(2020) Jiacheng Lou et al.   Molecular Cancer

EIF4A3-induced circular RNA ASAP1(circASAP1) promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/MEK1/ERK1/2 signaling

(2020) Yutian Wei et al.   NEURO-ONCOLOGY

A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

(2019) Xiao Zheng et al.   Molecular Cancer

CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress

(2019) Qidong Li et al.   Cell Metabolism

Past, present, and future of circ RNA s

(2019) Ines Lucia Patop et al.   EMBO JOURNAL

PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation

(2019) Shao-Ming Shen et al.   NATURE CELL BIOLOGY

Multiple roles of PTEN isoforms PTENα and PTENβ in cellular activities and tumor development

(2019) Hui Liang et al.   Science China-Life Sciences

N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

(2019) Ri-Xin Chen et al.   Nature Communications

PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target

(2019) Lisa Salvatore et al.   Cancers

Smad4/DPC4

(2018) Aoife J McCarthy et al.   JOURNAL OF CLINICAL PATHOLOGY

The functions and regulation of the PTEN tumour suppressor: new modes and prospects

(2018) Yu-Ru Lee et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Biogenesis, Functions, and Challenges of Circular RNAs

(2018) Xiang Li et al.   MOLECULAR CELL

EIF4A3-induced circular RNA MMP9 (circMMP9) acts as a sponge of miR-124 and promotes glioblastoma multiforme cell tumorigenesis

(2018) Renjie Wang et al.   Molecular Cancer

Circular RNAs in human cancer

(2017) Yumin Wang et al.   Molecular Cancer

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Circular RNAs in cancer: opportunities and challenges in the field

(2017) L S Kristensen et al.   ONCOGENE

PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription

(2017) Hui Liang et al.   Nature Communications

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

The emerging landscape of circular RNA in life processes

(2016) Shibin Qu et al.   RNA Biology

Emerging roles and context of circular RNAs

(2016) Amaresh C. Panda et al.   Wiley Interdisciplinary Reviews-RNA

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Co-migration of colon cancer cells and CAFs induced by TGFβ1 enhances liver metastasis

(2015) Idoia Gonzalez-Zubeldia et al.   CELL AND TISSUE RESEARCH

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs

(2015) Dawood B. Dudekula et al.   RNA Biology

PTENα, a PTEN Isoform Translated through Alternative Initiation, Regulates Mitochondrial Function and Energy Metabolism

(2014) Hui Liang et al.   Cell Metabolism

circBase: a database for circular RNAs

(2014) Petar Glažar et al.   RNA

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

PTEN function: the long and the short of it

(2014) Benjamin D. Hopkins et al.   TRENDS IN BIOCHEMICAL SCIENCES

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

A Secreted PTEN Phosphatase That Enters Cells to Alter Signaling and Survival

(2013) B. D. Hopkins et al.   SCIENCE

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Cancer treatment and survivorship statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

The functions and regulation of the PTEN tumour suppressor

(2012) Min Sup Song et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Predicting RNA-Protein Interactions Using Only Sequence Information

(2011) Usha K Muppirala et al.   BMC BIOINFORMATICS

MapSplice: Accurate mapping of RNA-seq reads for splice junction discovery

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

Targeting transforming growth factor-β signaling in liver metastasis of colon cancer

(2009) Bixiang Zhang et al.   CANCER LETTERS

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL