An updated SYSCILIA gold standard (SCGSv2) of known ciliary genes, revealing the vast progress that has been made in the cilia research field

Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes

(2021) Venkatramanan G. Rao et al.   GENESIS

PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress

(2020) Asma Boukhalfa et al.   Nature Communications

Motile cilia and airway disease

(2020) Marie Legendre et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Failure to reabsorb the primary cilium induces cellular senescence

(2019) Elizabeth P. Jeffries et al.   FASEB JOURNAL

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

(2019) Michaela Kunova Bosakova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation

(2019) Chia-Hsiang Chang et al.   DEVELOPMENTAL CELL

Spatial and proteomic profiling reveals centrosome‐independent features of centriolar satellites

(2019) Ladan Gheiratmand et al.   EMBO JOURNAL

CiliaCarta: An integrated and validated compendium of ciliary genes

(2019) Teunis J. P. van Dam et al.   PLoS One

SNX17 Recruits USP9X to Antagonize MIB1-Mediated Ubiquitination and Degradation of PCM1 during Serum-Starvation-Induced Ciliogenesis

(2019) Pengtao Wang et al.   Cells

Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome

(2018) Laura Bozal-Basterra et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts

(2018) Andreas Struchtrup et al.   Autophagy

CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog

(2018) Ganesh V. Pusapati et al.   DEVELOPMENTAL CELL

Nutrient sensing, growth and senescence

(2018) Bernadette Carroll et al.   FEBS Journal

TRRAP is a central regulator of human multiciliated cell formation

(2018) Zhao Wang et al.   JOURNAL OF CELL BIOLOGY

Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination

(2018) Sang Min Park et al.   NEURON

The deubiquitinating enzyme USP14 controls ciliogenesis and hedgehog signalling

(2018) Massa Filomena et al.   HUMAN MOLECULAR GENETICS

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Resting cells rely on the DNA helicase component MCM2 to build cilia

(2018) Teresa Casar Tena et al.   NUCLEIC ACIDS RESEARCH

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa

(2018) Adriana Buskin et al.   Nature Communications

Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing

(2017) Bernadette Carroll et al.   JOURNAL OF CELL BIOLOGY

KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability

(2017) Patricia L. Yeyati et al.   JOURNAL OF CELL BIOLOGY

Insights into Ciliary Genes and Evolution from Multi-Level Phylogenetic Profiling

(2017) Yannis Nevers et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Photoreceptor Cilia and Retinal Ciliopathies

(2017) Kinga M. Bujakowska et al.   Cold Spring Harbor Perspectives in Biology

Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein

(2017) Charles Anthony Scott et al.   PLoS Genetics

Primary Cilium-Autophagy-Nrf2 (PAN) Axis Activation Commits Human Embryonic Stem Cells to a Neuroectoderm Fate

(2016) Jiwon Jang et al.   CELL

Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway

(2016) Guoqiang Ma et al.   DEVELOPMENTAL CELL

Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia

(2016) Mingming Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zebrafish as a Model for Human Ciliopathies

(2016) Zhu Song et al.   Journal of Genetics and Genomics

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease

(2016) Dongmei Lu et al.   KIDNEY INTERNATIONAL

Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

(2016) Idil Orhon et al.   NATURE CELL BIOLOGY

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

(2016) Karsten Boldt et al.   Nature Communications

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface

(2015) Gagan D. Gupta et al.   CELL

Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3

(2015) Hannah Laura Gijs et al.   MOLECULAR BIOLOGY OF THE CELL

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

(2015) You Li et al.   NATURE

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome

(2015) Nils J. Lambacher et al.   NATURE CELL BIOLOGY

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

(2015) Gabrielle Wheway et al.   NATURE CELL BIOLOGY

Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking

(2015) Jongshin Kim et al.   Nature Communications

Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome

(2015) Susanne Roosing et al.   eLife

“Ciliophagy”

(2014) Suzanne M Cloonan et al.   Autophagy

RFX7 is required for the formation of cilia in the neural tube

(2014) Zarko Manojlovic et al.   MECHANISMS OF DEVELOPMENT

Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport

(2014) Daqing Jin et al.   NATURE CELL BIOLOGY

Coordinated genomic control of ciliogenesis and cell movement by RFX2

(2014) Mei-I Chung et al.   eLife

Myb promotes centriole amplification and later steps of the multiciliogenesis program

(2013) F. E. Tan et al.   DEVELOPMENT

IGF-1 Activates a Cilium-Localized Noncanonical Gβγ Signaling Pathway that Regulates Cell-Cycle Progression

(2013) Celine Yeh et al.   DEVELOPMENTAL CELL

A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

(2013) Bine H Villumsen et al.   EMBO JOURNAL

HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia

(2013) Albino Troilo et al.   EMBO REPORTS

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

(2013) Zaiming Tang et al.   NATURE

The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality

(2013) Marko T. Boskovski et al.   NATURE

TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

(2013) Christian Alexandro Clement et al.   Cell Reports

Mouse models of ciliopathies: the state of the art

(2012) D. P. Norris et al.   Disease Models & Mechanisms

1001 model organisms to study cilia and flagella

(2011) Laetitia Vincensini et al.   BIOLOGY OF THE CELL

Cildb: a knowledgebase for centrosomes and cilia

(2009) Olivier Arnaiz et al.   Database-The Journal of Biological Databases and Curation

AmiGO: online access to ontology and annotation data

(2008) Seth Carbon et al.   BIOINFORMATICS

CentrosomeDB: a human centrosomal proteins database

(2008) R. Nogales-Cadenas et al.   NUCLEIC ACIDS RESEARCH